Results 21 to 30 of about 10,301,033 (247)

Characterization of the rhesus macaque (Macaca mulatta) scrub typhus model: Susceptibility to intradermal challenge with the human pathogen Orientia tsutsugamushi Karp. [PDF]

PLoS Neglected Tropical Diseases, 2018
Scrub typhus is an important endemic disease in tropical Asia caused by Orientia tsutsugamushi for which no effective broadly protective vaccine is available. The successful evaluation of vaccine candidates requires well-characterized animal models and a
Piyanate Sunyakumthorn, Suwit J Somponpun, Rawiwan Im-Erbsin, Tippawan Anantatat, Kemajittra Jenjaroen, Susanna J Dunachie, Eric D Lombardini, Robin L Burke, Stuart D Blacksell, James W Jones, Carl J Mason, Allen L Richards, Nicholas P J Day, Daniel H Paris   +13 more
doaj   +1 more source

A case of Henoch-Schönlein purpura associated with scrub typhus

BMC Infectious Diseases, 2020
Background Henoch-Schönlein purpura (HSP) may be caused by several allergens. However, to date, HSP caused by Orientia tsutsugamushi has not been reported. Here, we report an unusual rash with features of HSP caused by Orientia tsutsugamushi.
Jae Hyoung Im, Suk Jin Choi, Moon-Hyun Chung, Seung Yun Lee, Young Kyoung Park, Hea Yoon Kwon, Ji Hyeon Baek, Jin-Soo Lee   +7 more
doaj   +1 more source

Emerging trends of scrub typhus disease in southern Rajasthan, India: A neglected public health problem

Journal of Vector Borne Diseases, 2022
Scrub typhus is the oldest known vector-borne zoonotic infectious disease in the world which is life-threatening for all age groups as it presents acute febrile illness along with multi-organ involvements and spread with the biting of infectious ...
Devendra Kumar, Saha Dev Jakhar
doaj   +1 more source

Orientia tsutsugamushi stimulates an original gene expression program in monocytes: relationship with gene expression in patients with scrub typhus. [PDF]

PLoS Neglected Tropical Diseases, 2011
Orientia tsutsugamushi is the causal agent of scrub typhus, a public health problem in the Asia-Pacific region and a life-threatening disease. O. tsutsugamushi is an obligate intracellular bacterium that mainly infects endothelial cells.
Wiwit Tantibhedhyangkul, Thanavadee Prachason, Duangdao Waywa, Adil El Filali, Eric Ghigo, Wanna Thongnoppakhun, Didier Raoult, Yupin Suputtamongkol, Christian Capo, Chanin Limwongse, Jean-Louis Mege   +10 more
doaj   +1 more source

Concurrent Scrub Typhus, Dengue, and Leptospirosis: A Rare Triple Co-Infection: A Case Report and Comprehensive Literature Review. [PDF]

Clin Case Rep
ABSTRACT In endemic areas, acute undifferentiated febrile illness has a wide differential with overlapping features that can lead to misdiagnosis. Although triple co‐infection with scrub typhus, dengue, and leptospirosis is extremely rare, high clinical suspicion and early detection are vital to avoid delayed treatment, multi‐organ dysfunction, and ...
Jha SK, Dahal B, Adhikari A, Basnet KS, Singh S, Acharya M.   +5 more
europepmc   +2 more sources

Symbiosis in an overlooked microcosm: a systematic review of the bacterial flora of mites [PDF]

, 2015
A dataset of bacterial diversity found in mites was compiled from 193 publications (from 1964 to January 2015). A total of 143 mite species belonging to the 3 orders (Mesostigmata, Sarcoptiformes and Trombidiformes) were recorded and found to be ...
Chaisiri, Kittipong, Makepeace, Benjamin L, McGarry, John W, Morand, Serge   +3 more
core   +2 more sources

Survival and Growth of Orientia tsutsugamushi in Conventional Hemocultures

Emerging Infectious Diseases, 2016
Orientia tsutsugamushi, which requires specialized facilities for culture, is a substantial cause of disease in Asia. We demonstrate that O. tsutsugamushi numbers increased for up to 5 days in conventional hemocultures.
Sabine Dittrich, Elizabeth Card, Weerawat Phuklia, Williams E. Rudgard, Joy Silousok, Phonelavanh Phoumin, Latsaniphone Bouthasavong, Sarah Azarian, Viengmon Davong, David A.B. Dance, Manivanh Vongsouvath, Rattanaphone Phetsouvanh, Paul N. Newton   +12 more
doaj   +1 more source

CD8+ T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection. [PDF]

PLoS Neglected Tropical Diseases, 2017
Scrub typhus, caused by a Gram-negative obligately intracellular coccobacillus, Orientia tsutsugamushi, is a long neglected but important tropical disease. Orientia tsutsugamushi causes illness in one million people each year, and 1 billion people are at
Guang Xu, Nicole L Mendell, Yuejin Liang, Thomas R Shelite, Yenny Goez-Rivillas, Lynn Soong, Donald H Bouyer, David H Walker   +7 more
doaj   +1 more source

Orientia tsutsugamushi ankyrin repeat-containing protein family members are Type 1 secretion system substrates that traffic to the host cell endoplasmic reticulum [PDF]

, 2015
Scrub typhus is an understudied, potentially fatal infection that threatens one billion persons in the Asia-Pacific region. How the causative obligate intracellular bacterium, Orientia tsutsugamushi, facilitates its intracellular survival and ...
Beare, Paul A., Beyer, Andrea R., Carlyon, Jason A., Evans, Sean M., Ge, Hong, Heinzen, Robert A., Larson, Charles L., Richards, Allen L., Rodino, Kyle G., Singh, Smita, VieBrock, Lauren   +10 more
core   +3 more sources

LEPTOTROMBIDIUM DELIENSE INFESTATION IN DOMESTIC DOGS FROM INDIA, A VECTOR OF SCRUB TYPHUS: A CASE REPORT [PDF]

Exploratory Animal and Medical Research, 2022
Scrub typhus is a vector-borne, zoonotic disease caused by Orientia tsutsugamushi. Several members of the genus Leptotrombidium have gained importance due to their potential role as vectors as well as reservoirs for O. tsutsugamushi.
G. E. Chethan , Kalyan Sarma , Nikitasha Bora , H. V. Manjunathachar , Neeraj Thakur, Snehil Gupta , Champak Deka , S. N. Chaithra , Vijayakumar Jawalagatti , J. B. Rajesh , Kuldeep Dhama   +10 more
doaj   +1 more source