Results 61 to 70 of about 10,301,033 (247)

Differences in clinical features according to Boryoung and Karp genotypes of Orientia tsutsugamushi.

PLoS ONE, 2011
BackgroundScrub typhus is an infectious disease caused by Orientia tsutsugamushi. The differences in virulence of O. tsutsugamushi prototypes in humans are still unknown.
Dong-Min Kim, Na Ra Yun, Ganesh Prasad Neupane, Sung Heui Shin, So Yeon Ryu, Hee Jung Yoon, Seong Heon Wie, Woo Jin Kim, Chang Youl Lee, Jong Soo Choi, Tae Young Yang   +10 more
doaj   +1 more source

Scrub Typhus: No Longer Restricted to the Tsutsugamushi Triangle

Tropical Medicine and Infectious Disease, 2018
Scrub typhus is the most important rickettsial disease in the world. Its previous endemic region was considered to be in Asia, Australia and islands in the Indian and Pacific Oceans; this area was referred to as the Tsutsugamushi Triangle.
Ju Jiang, Allen L. Richards
doaj   +1 more source

Group 2 Innate Lymphoid Cells Are Redundant in Experimental Renal Ischemia-Reperfusion Injury. [PDF]

, 2019
Acute kidney injury (AKI) can be fatal and is a well-defined risk factor for the development of chronic kidney disease. Group 2 innate lymphoid cells (ILC2s) are innate producers of type-2 cytokines and are critical regulators of homeostasis in ...
Cameron, Guy JM, Cautivo, Kelly M, Deshpande, Aniruddh V, Foster, Paul S, Hansbro, Philip M, Jiang, Simon H, Loering, Svenja, McKenzie, Andrew NJ, Molofsky, Ari B, Starkey, Malcolm R   +9 more
core   +4 more sources

Drug Design and Delivery for Intracellular Bacteria: Emerging Paradigms

Drug Development Research, Volume 86, Issue 8, December 2025.
ABSTRACT Intracellular bacteria exploit host cell niches, such as lysosomes, phagosomes, cytosol, entire cells, and even erythrocytes, to evade immune clearance and escape conventional antibiotics. These environments pose numerous therapeutic challenges, including crossing host cell membranes, navigating endosomal trafficking, tolerating acidic and ...
Babatunde Ibrahim Olowu, Maryam Ebunoluwa Zakariya, Abdulmuheez Abiola Abdulkareem, Olalekan Toheeb Okewale, Muhammad Halima Idris, Halimah Oluwayemisi Olayiwola   +5 more
wiley   +1 more source

A CRISPR-Cas12a-based universal rapid scrub typhus diagnostic method targeting 16S rRNA of Orientia tsutsugamushi.

PLoS Neglected Tropical Diseases
Scrub typhus is caused by Orientia tsutsugamushi infection and occurs frequently in an area called the Tsutsugamushi Triangle. Currently, there is no vaccine for O. tsutsugamushi, and its infection is treated with antibiotics such as doxycycline.
Bum Ju Park, Sang Taek Heo, Misun Kim, Jeong Rae Yoo, Eun Jin Bae, Su Yeon Kang, Sunghoon Park, Kyeo Re Han, Keun Hwa Lee, Jae Myun Lee, Hyeyoung Lee, Yoon-Jae Song   +11 more
doaj   +1 more source

High prevalence of Rickettsia africae variants in Amblyomma variegatum ticks from domestic mammals in rural western Kenya: implications for human health [PDF]

, 2014
Tick-borne spotted fever group (SFG) rickettsioses are emerging human diseases caused by obligate intracellular Gram-negative bacteria of the genus Rickettsia.
Ade, Fredrick, Breiman, Robert F., Cleaveland, Sarah, Cutler, Sally J., Feikin, Daniel R., Jiang, Ju, Knobel, Darryn L., Maina, Alice N., Mpoke, Solomon, Ng'ang'a, Zipporah, Njenga, M. Kariuki, Ogola, Eric, Omulo, Sylvia A., Richards, Allen L.   +13 more
core   +3 more sources

Retrospective study of Shimokoshi-type tsutsugamushi disease in Akita Prefecture, Japan

, 2014
We confirmed 15 cases of Shimokoshi-type tsutsugamushi disease from 1992 to 2008 in Akita prefecture, Japan. Clinical findings of these cases showed diversity, including mild to severe cases.
Hiroko Sato, Chihiro Shibata, H. Saito, T. Suto   +3 more
semanticscholar   +1 more source

ON THE NYMPH AND PROSOPON OF THE TSUTSUGAMUSHI, LEPTOTROMBIDIUM AKAMUSHI, N. SP. (TROMBIDIUM AKAMUSHI BRUMPT), CARRIER OF THE TSUTSUGAMUSHI DISEASE

Journal of Experimental Medicine, 1917
Nomenclature. As mentioned above, the prosopon and the nymph of the tsutsugamushi have many characteristics which distinguish it from the other trombidia.
M. Nagayo, Y. Miyagawa, T. Mitamura, A. Imamura   +3 more
semanticscholar   +1 more source

Scrub Typhus: Historic Perspective and Current Status of the Worldwide Presence of Orientia Species

Tropical Medicine and Infectious Disease, 2020
Scrub typhus and its etiological agents, Orientia species, have been around for a very long time. Historical reference to the rickettsial disease scrub typhus was first described in China (313 AD) by Hong Ge in a clinical manual (Zhouhofang) and in Japan
Allen L. Richards, Ju Jiang
doaj   +1 more source

An Alternative Splicing Variant of the Mixed-Lineage Leukemia 5 Protein Is a Cellular Adhesion Receptor for ScaA of Orientia tsutsugamushi

mBio, 2023
Scrub typhus is a mite-borne disease caused by the obligately intracellular bacterium Orientia tsutsugamushi. We previously demonstrated that ScaA, an autotransporter membrane protein of O.
Yen Thi Hai Nguyen, Chaewon Kim, Hong-Il Kim, Yuri Kim, Sang-Eun Lee, Sunghoe Chang, Na-Young Ha, Nam-Hyuk Cho   +7 more
doaj   +1 more source