Results 111 to 120 of about 35,493 (223)

When NCX switches sides: Experimental and computational insights into Ca2+ regulation in the heart

The Journal of Physiology, EarlyView.
Abstract figure legend Due to its presence inside the dyadic cleft, Na+/Ca2+ exchanger (NCX) builds a functional unit together with L‐type calcium channels and ryanodine receptors in the dyadic cleft. NCX acts bidirectionally (forward and reverse mode) dependent on extracellular calcium ([Ca2+]o) and sodium ([Na+]o) concentrations and the membrane ...
Wilhelm Neubert, Judith Hüttemeister, Paulina Sander, Nagaiah Chamakuri, Felix Hohendanner, Martin Falcke, Frank R. Heinzel   +6 more
wiley   +1 more source

Hyperpolarized MRI Detects Increased [1‐13C]Pyruvate Metabolism in Early Liver Regeneration

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
Hyperpolarized [1‐13C]pyruvate MRI detected increased pyruvate‐to‐lactate and pyruvate‐to‐alanine exchange during early liver regeneration following 70% partial hepatectomy in rats. These findings support the use of hyperpolarized MRI for noninvasive assessment of regenerative metabolism.
Uffe Kjærgaard, Andrea Lund, Lotte Bonde Bertelsen, Esben Søvsø Szocska Hansen, Katrine Holm Andersen, Steffen Ringgaard, Jens Randel Nyengaard, Frank Viborg Mortensen, Christoffer Laustsen   +8 more
wiley   +1 more source

Sensitivity of Large‐Scale Hydrological Predictions to Precipitation Phase Partitioning Methods Under a Changing Climate

Hydrological Processes, Volume 40, Issue 7, July 2026.
Future warming shifts precipitation from snow to rain across the Saskatchewan River Basin, reducing snow water equivalent and advancing snowmelt timing. Differences among precipitation phase‐partitioning methods propagate from snowpack accumulation to runoff magnitude and timing, producing earlier spring flows and higher peak discharge.
Fuad Yassin, John W. Pomeroy, Alain Pietroniro, Bruce Davison, Mohamed Elshamy, Zelalem Tesemma   +5 more
wiley   +1 more source

Patient‐Reported Swallowing Outcomes ≥5 Years After Neoadjuvant Chemotherapy and Transoral Robotic Surgery for HPV‐positive Oropharyngeal Carcinoma

OTO Open, Volume 10, Issue 3, July-September 2026.
Abstract Objective To evaluate long‐term swallowing outcomes in patients with HPV‐associated oropharyngeal squamous cell carcinoma (HPV + OPSCC) following neoadjuvant chemotherapy (NAC) and transoral robotic surgery (TORS) (NAC + S). Study Design Retrospective cross‐sectional study. Setting Single academic institution. Methods Patients completed the MD
Sandhya Ganesan, Sana Smaoui, Leena Zitoun, Tyler P. Tufano, Esther Lee, Punam Thakkar, Arjun Joshi   +6 more
wiley   +1 more source

Molecular Interplay of PARN and Telomerase: Tail Modifiers and Disease Implications

WIREs RNA, Volume 17, Issue 4, July/August 2026.
Schematic representation of the molecular interplay between PARN, telomerase‐associated, and the involvement of p53 in regulating telomere maintenance and genome stability. The top panel shows how normal PARN levels are involved in regulating p53 levels and balanced telomerase activity through their regulatory interaction with TERC and TERRA, thus ...
Sujitha Felicitus, Shalon Suzanne Pinto, Sai Samanvitha Madagundapalli Ramakrishna, Dechamma Pandyanada Nanjappa, Gunimala Chakraborty, Anirban Chakraborty   +5 more
wiley   +1 more source

Diaphragm‐specific effects of L‐citrulline in mdx mice highlight its potential as adjuvant of standard therapy in Duchenne muscular dystrophy

British Journal of Pharmacology, Volume 183, Issue 13, Page 3866-3884, July 2026.
Abstract Background and Purpose The absence of the protein dystrophin in Duchenne muscular dystrophy (DMD) leads to progressive muscle weakness, failing regeneration and deregulation of nitric oxide (NO) signalling. We focused on L‐citrulline, a precursor of L‐arginine, required for NO production in muscle, which is reduced in dystrophic mdx muscle ...
Lisamaura Tulimiero, Brigida Boccanegra, Paola Mantuano, Antonietta Mele, Michela De Bellis, Roberta Lenti, Francesca Sanarica, Santa Cirmi, Elena Conte, Ornella Cappellari, Amber E. Sherrard, Ardawna Green, Mira Srinivasa, Marta L. Fiorotto, Annamaria De Luca   +14 more
wiley   +1 more source

Platelet Transfusion Is Associated With Increased Thrombosis and In‐Hospital Mortality Among Patients Hospitalized With Platelet Consumptive Disorders

European Journal of Haematology, Volume 117, Issue 1, Page 245-257, July 2026.
ABSTRACT Background Platelet transfusion is commonly used to reduce bleeding risk in platelet consumptive disorders. However, platelets may also promote thromboinflammatory pathways, and contemporary data evaluating the association between platelet transfusion, thrombosis, and mortality in this population are limited.
Manas Pustake, Shubhangi Deoker, Veeravenkata Garikiparthy, Kunal Sharma, Lakshmi Kattamuri, Abhizith Deoker, Abhinav Deol   +6 more
wiley   +1 more source

Personalisation‐Privacy Paradox: Systematic Review and Survey Evidence on Personal Data Stores

Expert Systems, Volume 43, Issue 7, July 2026.
ABSTRACT The personalisation–privacy paradox captures the tension between using personal data for personalised services and respecting individuals' privacy. This study adopts a holistic research framework to clarify the paradox's core challenges, review existing approaches, and examine a user‐centric solution.
Ming‐Wei Hsu, Glenn Parry, Irene Ng
wiley   +1 more source

Real-World Analysis of Clinical Characteristics, Treatment Outcomes, and the Novel Predictive Model for Patients with Thrombotic Thrombocytopenic Purpura (TTP) and TTP-Like Syndrome

Vascular Health and Risk Management
Mengya Lv,1 Xing Hu,2 Lijun Zhu,2 Hui Xu,2 Erling Chen,2 Na Zhao,2 Juan Tong,2 Changcheng Zheng1,2 1Department of Hematology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei, People’s Republic of China; 2Department of Hematology ...
Lv M, Hu X, Zhu L, Xu H, Chen E, Zhao N, Tong J, Zheng C   +7 more
doaj  

Myth or Merit? A Reassessment of the “Monks From Afar” Effect in Taiwan's Dual‐Track Talent Policy in Higher Education

Higher Education Quarterly, Volume 80, Issue 3, July 2026.
ABSTRACT In response to global talent competition and the goal of building world‐class universities, Taiwan's government introduced talent policies to enhance research capacity and international visibility. This study employs a mixed‐methods design to analyse the distribution of four main awardee types in alignment with Taiwan's dual talent policies ...
Angela Yung Chi Hou, Edward Hung Cheng Su, Sally Shu Mei Chao, Arianna Fang Yu Lin, Pock Yi Feng, Christopher Hill   +5 more
wiley   +1 more source