Results 91 to 100 of about 35,493 (223)

Approximation algorithms for TTP(2)

Mathematical Methods of Operations Research, 2012
We consider the traveling tournament problem, which is a well-known benchmark problem in tournament timetabling. It consists of designing a schedule for a sports league of n teams such that the total traveling costs of the teams are minimized. The most important variant of the traveling tournament problem imposes restrictions on the number of ...
Clemens Thielen, Stephan Westphal
openaire   +2 more sources

Clinical burden and healthcare resource use of congenital thrombotic thrombocytopenic purpura in England: A linked primary and secondary care data analysis

British Journal of Haematology, EarlyView.
Summary Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra rare haematological disorder. This study aimed to estimate the clinical burden, healthcare resource use (HCRU) and associated costs of cTTP in England using primary and secondary care data. A retrospective cohort study was undertaken using the Clinical Practice Research Datalink (
Erin Barker, Will Lester, Heather Riley, Monica Garrett, Amie Padhiar, Annie Berkley, Sudhakar Manne, Umesh Doobaree, Oliver Heard   +8 more
wiley   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Role of plasma exchange in a post-partum case of severe thrombotic thrombocytopenic purpura with acute kidney injury

Journal of Family Medicine and Primary Care
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disease present with the classic pentad of microangiopathic hemolytic anemia (MAHA), fever, neurologic changes, thrombocytopenia, and renal dysfunction.
Jyoti Bharti, Tulika Chandra, Archana Solanki, Ashutosh Singh, D. Himanshu Reddy, Mallika Agarwal   +5 more
doaj   +1 more source

SlideSAVR: Enabling Live Analysis during Data Presentations via Multimodal Sketching and Voice Input

Computer Graphics Forum, EarlyView.
Abstract Interpersonal communication in data science can yield sought‐after insights, but presentation environments are often not conducive for live analysis, forcing the process to move offline. Through a formative survey with 16 participants, we identified both technical (e.g., complexity of tools) and psychological (e.g., pressure of programming ...
C. Han, M.M. Tanjim, S. Guo, C. Dierk, K.E. Isaacs, J. Hoffswell   +5 more
wiley   +1 more source

Time to positivity in blood cultures of adults with Streptococcus pneumoniae bacteremia

BMC Infectious Diseases, 2006
Background previous studies have established that bacterial blood concentration is related with clinical outcome. Time to positivity of blood cultures (TTP) has relationship with bacterial blood concentration and could be related with prognosis. As there
Ansorena Luis, Garrido Jose, Rodríguez-Lera María, Peralta Galo, Roiz María   +4 more
doaj   +1 more source

Risk Factors of Blood Culture Positivity and Mortality in Bloodstream Infections: A Population‐Based Study of Patients With B‐Cell Malignancies

European Journal of Haematology, EarlyView.
ABSTRACT Background Bloodstream infections remain a major cause of mortality among cancer patients. Pathogen surveillance and risk stratification tools are key to improved management. This study describes trends in causative pathogens and explores risk factors for positive blood cultures (PBCs) and post‐infection mortality in cancer patients.
Mathias Holmsgaard Eskesen, Alexander Djupnes Fuglkjær, Tarec Christoffer El‐Galaly, Paw Jensen, Izabela Ewa Nielsen, Laurids Østergaard Poulsen, Mikkel Runason Simonsen, Kirstine Kobberøe Søgaard   +7 more
wiley   +1 more source

Re-thinking the role of intellectual property in nano-strategy

Nanotechnology Reviews, 2012
In two past studies we observed and analyzed a group of European new and adolescent ventures, looking in particular at how they were about exploiting nanotechnology-based business opportunities, what was the role of intellectual property rights (IPRs ...
Giordani Sara
doaj   +1 more source

Spinoza on Humans as Social Animals

European Journal of Philosophy, EarlyView.
Abstract Spinoza repeatedly suggests that humans are set apart from other animals by their rational and moral abilities. Yet he disparages the traditional definition of the human as a ‘rational animal’ and several of his other views suggest that these abilities are not sufficient by themselves to characterize human nature.
Ruben Noorloos
wiley   +1 more source

ADAMTS13 in the New Era of TTP

International Journal of Molecular Sciences
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening, often immune-mediated disease that affects 2–13 persons per million per year. Hemolytic anemia, thrombocytopenia, and end-organ damage due to the formation of microthrombi are characteristic of TTP.
Anna Papakonstantinou, Panagiotis Kalmoukos, Aikaterini Mpalaska, Evaggelia-Evdoxia Koravou, Eleni Gavriilaki   +4 more
openaire   +2 more sources