Results 71 to 80 of about 35,493 (223)

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa, Birhanetensay Masresha Altaye, Yuh‐Pyng Sher   +2 more
wiley   +1 more source

Ripeness Levels and Their Relations with the Success of the Negotiation Method: CPP-NPA, TTP, IRA

Gazi Akademik Bakış, 2023
Conflict arises for a variety of reasons. Parties may fail to achieve clear success in the conflict process and achieve their goals. In such a situation, conflict causes the parties to reach the mutually hurting stalemate.
Emrah KAYA
doaj  

Remarks on the Maximal Regularity for Parabolic Boundary Value Problems With Inhomogeneous Data

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT Inspired by Ogawa‐Shimizu and Chen‐Liang‐Tsai on the second and first order derivative estimates of solutions of the heat equation in the upper half space with boundary data in homogeneous Besov spaces, we extend the estimates to any order of derivatives, including fractional derivatives.
Hui Chen, Su Liang, Tai‐Peng Tsai
wiley   +1 more source

Lipopolysaccharide tolerance attenuates inflammatory responses by increasing heme oxygenase 1 and tristetraprolin expression in Raw264.7 macrophages

Journal of Advanced Biotechnology and Experimental Therapeutics, 2018
Inflammation is associated with the progression of a variety of diseases. Lipopolysaccharides (LPS) tolerance is recognized to reduce proinflammatory responses.
Akhi Moni
doaj   +1 more source

TTP: Tool for Tumor Progression [PDF]

, 2013
In this work we present a flexible tool for tumor progression, which simulates the evolutionary dynamics of cancer. Tumor progression implements a multi-type branching process where the key parameters are the fitness landscape, the mutation rate, and the average time of cell division.
Johannes G. Reiter, Ivana Bozic, Krishnendu Chatterjee, Martin A. Nowak   +3 more
openaire   +2 more sources

DynaTOF: Time‐Resolved Noncontrast Cerebral MR Angiography Using Spatially Modulated RF Saturation

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a time‐resolved extension of three‐dimensional time‐of‐flight MR angiography, termed Dynamic TOF (DynaTOF), that exploits intrinsic RF saturation behavior to enable noncontrast visualization of cerebrovascular hemodynamics.
Naoyuki Takei, Keita Fujii, Xucheng Zhu, Yuichi Suzuki, Satoru Miyawaki, Motoyuki Umekawa, Satoshi Koizumi, Tetsuya Wakayama, Shiori Amemiya, Osamu Abe   +9 more
wiley   +1 more source

Neutrino oscillations and scattering theory

Journal of High Energy Physics
We derive the neutrino oscillation probability in vacuum using scattering theory methods developed earlier in the context of collider physics [1–3]. It is computed from Feynman diagrams that combine neutrino production and detection processes into a ...
Ilian Dobrev, Kirill Melnikov, Thomas Schwetz   +2 more
doaj   +1 more source

Digital fire technologies and community networks: Cultivating just sociotechnical practices for living with planetary change

People and Nature, EarlyView.
Abstract Fires are expanding in frequency and intensity worldwide due to climate change and land‐use transformations. At the same time, fire often plays a regenerative role in ecosystems. Traditional and cultural practices incorporate fire use for landscape management and landscape renewal. In this complex matrix of fire ecologies, digital technologies
Jennifer Gabrys, Paula Tiara Torres, Pablo González Rivas   +2 more
wiley   +1 more source

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

PROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan, Clinton J. Bradfield, Sandhini Saha, Sung Hwan Yoon, Iain D. C. Fraser, Aleksandra Nita‐Lazar   +5 more
wiley   +1 more source

A sample size analysis of a mathematical model of longitudinal tumor volume and progression‐free survival for Bayesian individual dynamic predictions in recurrent high‐grade glioma

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 495-509, March 2025.
Abstract Patients with recurrent high‐grade glioma (rHGG) have a poor prognosis with median progression‐free survival (PFS) of <7 months. Responses to treatment are heterogenous, suggesting a clinical need for prognostic models. Bayesian data analysis can exploit individual patient follow‐up imaging studies to adaptively predict the risk of progression.
Daniel J. Glazar, Solmaz Sahebjam, Hsiang‐Husan M. Yu, Dung‐Tsa Chen, Menal Bhandari, Heiko Enderling   +5 more
wiley   +1 more source