ADAMTS13, TTP and Beyond [PDF]
Hereditary Genetics, 2013 Copyright: © 2012 Zheng XL. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Elevated plasma neutrophil elastase concentration is associated with disease activity in patients with thrombotic thrombocytopenic purpura. [PDF]
, 2015 INTRODUCTION: Genetic and autoimmune risk factors contribute to the development of thrombotic thrombocytopenic purpura (TTP) but triggers are needed to bring about acute disease.
Brill +44 more
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Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay. [PDF]
, 2015 Skeletal muscle satellite cells in their niche are quiescent and upon muscle injury, exit quiescence, proliferate to repair muscle tissue, and self-renew to replenish the satellite cell population.
Blackshear, Perry J +7 more
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Transregionalism in US Foreign Policy: Comparative Analysis of TPP and TTIP Geopolitics
Сравнительная политика, 2017 The decision of US President Donald Trump to withdraw from the Trans-Pacifi c Partnership and the sluggish negotiations on Transatlantic Trade and Investment Partnership have fueled the debate on the future trajectories of American foreign policy in its ...
Denis A. Kuznetsov
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Infection frequently triggers thrombotic microangiopathy in patients with preexisting risk factors : a single-institution experience [PDF]
, 2010 Thrombotic microangiopathies are rare conditions characterized by microangiopathic hemolytic anemia, microthrombi, and multiorgan insult. The disorders, which include hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, are often acute and ...
Catlow, Jamie +4 more
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Proceedings of the 14th conference on Computational linguistics -, 1992 In this paper we describe TTP, a fast and robust natural language parser which can analyze written text and generate regularized parse structures for sentences and phrases at the speed of approximately 0.5 sec/sentence, or 44 word per second. The parser is based on a wide coverage grammar for English, developed by the New York University's Linguistic ...
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Cosolver2B: An Efficient Local Search Heuristic for the Travelling Thief Problem
, 2016 Real-world problems are very difficult to optimize. However, many researchers have been solving benchmark problems that have been extensively investigated for the last decades even if they have very few direct applications.
Ahiod, Belaïd, Yafrani, Mohamed El
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Ab initio derivation of multi-orbital extended Hubbard model for molecular crystals [PDF]
, 2012 From configuration interaction (CI) ab initio calculations, we derive an effective two-orbital extended Hubbard model based on the gerade (g) and ungerade (u) molecular orbitals (MOs) of the charge-transfer molecular conductor (TTM-TTP)I_3 and the single-
Marie-Laure Bonnet +6 more
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Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
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