Results 31 to 40 of about 51,249 (253)

ADAMTS13, TTP and Beyond [PDF]

open access: yesHereditary Genetics, 2013
Copyright: © 2012 Zheng XL. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
openaire   +2 more sources

Use of rituximab for treatment of HIV-infected patients with hematological disorders

open access: yesКлиническая онкогематология, 2013
Rituximab (MabThera) is one of the most powerful drug with selective action on B-cells. The drug suppresses the polyclonal antibody response to own antigens in autoimmune diseases. For lymphatic tumors it selectively acts on tumors of B-cells.
A. V. Pivnik
doaj   +1 more source

Synthesis and Biochemical Characterization of Tricyclothymidine Triphosphate (tc-TTP) [PDF]

open access: yes, 2014
Tricyclo-DNA (tc-DNA) is a conformationally restricted oligonucleotide analogue that exhibits promising properties as a robust antisense agent. Here we report on the synthesis and biochemical characterization of tc-TTP, the triphosphate of a tc-DNA ...
Leumann, Christian, Hollenstein, Marcel
core   +1 more source

HUS and TTP in Children [PDF]

open access: yesPediatric Clinics of North America, 2013
This review describes the epidemiology, pathophysiology, presentation, clinical causes, treatment, and long-term prognosis of pediatric patients who present with thrombotic microangiopathy. The focus is on hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, the most common phenotypes of thrombotic microangiopathy.
openaire   +2 more sources

A case of thrombotic microangiopathy and acute demyelinating central nervous system lesions as the first manifestation of systemic lupus erythematosus

open access: yesSri Lanka Journal of Medicine, 2021
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder with a relapsing and remitting course and multi- organ involvement which can present with a wide range of neuropsychiatric manifestations. Acute disseminating encephalomyelitis (ADEM) is
K. D. Ellepola   +5 more
doaj   +1 more source

TTP [PDF]

open access: yesProceedings of the 14th conference on Computational linguistics -, 1992
In this paper we describe TTP, a fast and robust natural language parser which can analyze written text and generate regularized parse structures for sentences and phrases at the speed of approximately 0.5 sec/sentence, or 44 word per second. The parser is based on a wide coverage grammar for English, developed by the New York University's Linguistic ...
openaire   +2 more sources

Thrombotic thrombocytopenic pupura (TTP) dinner symposium proceedings.

open access: yes, 2016
Answering TTP was established to engage the thrombotic thrombocytopenic purpura (TTP) community to further the common goals of patient support, education of patients and medical professionals, and the funding of research to improve the treatment and care
Kremer Hovinga, Johanna Anna   +4 more
core   +1 more source

Monolithic Oxidation Enables Ultrathin Vertically Graded Tantalum Oxide for Low‐Voltage, Low‐Variability Memristive Switching

open access: yesAdvanced Functional Materials, EarlyView.
Monolithic UV‐ozone oxidation of Ta forms an ultrathin Ta2O5/TaOx bilayer enabling resistive switching with a vertical defect gradient. A stoichiometric surface layer over an oxygen‐deficient sublayer promotes localized filament nucleation near the top interface, enabling low‐voltage operation, and reduced cycle‐to‐cycle variability.
Seunghoon Yang   +11 more
wiley   +1 more source

How I treat thrombotic thrombocytopenic purpura and atypical haemolytic uraemic syndrome [PDF]

open access: yes, 2014
Thrombotic thrombocytopenic purpura (TTP) and atypical haemolytic uraemic syndrome (aHUS) are acute, rare life-threatening thrombotic microangiopathies that require rapid diagnosis and treatment.
Goodship, T, Scully, M
core  

Targeting Tex10 Overcomes Oxaliplatin Resistance by Competitively Disrupting the Non‐Canonical BAF Complex in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu   +9 more
wiley   +1 more source

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