Results 41 to 50 of about 51,249 (253)
Transregionalism in US Foreign Policy: Comparative Analysis of TPP and TTIP Geopolitics
The decision of US President Donald Trump to withdraw from the Trans-Pacifi c Partnership and the sluggish negotiations on Transatlantic Trade and Investment Partnership have fueled the debate on the future trajectories of American foreign policy in its ...
Denis A. Kuznetsov
doaj +1 more source
F‐Type Pyocin Versus Phage λ Tail: Conserved Hub, Divergent Fibers
Near‐atomic cryo‐EM structures of a Gram‐negative F‐type pyocin reveal a conserved tail tip architecture shared with bacteriophage λ together with a previously unrecognized side‐fiber attachment mode. These findings provide new insight into tailocin assembly and host recognition and establish a structural framework for engineering precision ...
Zhiwei Gu +5 more
wiley +1 more source
Objective: This study aimed to evaluate the clinical spectrum, treatment characteristics, and outcomes of therapeutic apheresis (TA) procedures performed at a tertiary care university hospital, with particular emphasis on thrombotic thrombocytopenic ...
Berrin Balık +4 more
doaj +1 more source
Strange or estranged bedfellows? Discerning the Taliban-Pakistan relationship [PDF]
The Afghan Taliban and Pakistan are often touted as two sides of the same coin, given the latter’s pivotal role in supporting the movement since its emergence in 1994, and subsequently in resurrecting it as a potent insurgent force against NATO.
Raghav Sharma
doaj +1 more source
TTP-HUS Associated with Sunitinib [PDF]
Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) is a rare condition that is severe and may be fatal. Adverse reactions to drugs increasingly are reported as probable causes of TTP-HUS. Many chemotherapeutic agents have also been implicated in causing TTP-HUS. We reported a woman with metastatic renal cell carcinoma who presented
Moon Ki, Choi +3 more
openaire +2 more sources
The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi +6 more
wiley +1 more source
From Intelligence gathering to Cyber Threat Detection [PDF]
Intelligence plays a key role in the detection and neutralisation of threat actors in cyberspace, particularly when dealing with advanced ones. However, the relationship between intelligence and the final detection capabilities is not well–defined in ...
Antonio VILLALON-HUERTA +2 more
doaj
ABSTRACT Immune‐mediated thrombotic thrombocytopenic purpura (iTTP) is a life‐threatening thrombotic microangiopathy characterized by acute neurological manifestations and long‐term sequelae related to microvascular brain injury. Cerebral small vessel disease (cSVD), detectable on MRI through lacunes, microbleeds, white matter hyperintensities, and ...
Addolorata Truma +13 more
wiley +1 more source
Dark photons with kinetic mixing are compelling mediators for the interactions between dark matter and Standard Model particles. While most experimental searches focus on fully visible or fully invisible decays of dark photons, we explore processes that ...
Francesca Acanfora, Felix Kahlhoefer
doaj +1 more source
Bottom-quark effects in Higgs production at intermediate transverse momentum
We provide a precise description of the Higgs boson transverse momentum distribution including top and bottom quark contributions, that is valid for transverse momenta in the range m b ≲ p ⊥ ≲ m t , where m b and m t are the bottom and top quark masses.
Fabrizio Caola +5 more
doaj +1 more source

