Results 41 to 50 of about 51,249 (253)

Transregionalism in US Foreign Policy: Comparative Analysis of TPP and TTIP Geopolitics

open access: yesСравнительная политика, 2017
The decision of US President Donald Trump to withdraw from the Trans-Pacifi c Partnership and the sluggish negotiations on Transatlantic Trade and Investment Partnership have fueled the debate on the future trajectories of American foreign policy in its ...
Denis A. Kuznetsov
doaj   +1 more source

F‐Type Pyocin Versus Phage λ Tail: Conserved Hub, Divergent Fibers

open access: yesAdvanced Science, EarlyView.
Near‐atomic cryo‐EM structures of a Gram‐negative F‐type pyocin reveal a conserved tail tip architecture shared with bacteriophage λ together with a previously unrecognized side‐fiber attachment mode. These findings provide new insight into tailocin assembly and host recognition and establish a structural framework for engineering precision ...
Zhiwei Gu   +5 more
wiley   +1 more source

Plasmapheresis Activity of a Tertiary Referral Centre Indicating Wide-Spread Interdisciplinary and Safe Use of Therapeutic Plasma Exchange, with an Emphasis on Thrombotic Thrombocytopenic Purpura

open access: yesCam & Sakura Medical Journal
Objective: This study aimed to evaluate the clinical spectrum, treatment characteristics, and outcomes of therapeutic apheresis (TA) procedures performed at a tertiary care university hospital, with particular emphasis on thrombotic thrombocytopenic ...
Berrin Balık   +4 more
doaj   +1 more source

Strange or estranged bedfellows? Discerning the Taliban-Pakistan relationship [PDF]

open access: yesRevista UNISCI
The Afghan Taliban and Pakistan are often touted as two sides of the same coin, given the latter’s pivotal role in supporting the movement since its emergence in 1994, and subsequently in resurrecting it as a potent insurgent force against NATO.
Raghav Sharma
doaj   +1 more source

TTP-HUS Associated with Sunitinib [PDF]

open access: yesCancer Research and Treatment, 2008
Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) is a rare condition that is severe and may be fatal. Adverse reactions to drugs increasingly are reported as probable causes of TTP-HUS. Many chemotherapeutic agents have also been implicated in causing TTP-HUS. We reported a woman with metastatic renal cell carcinoma who presented
Moon Ki, Choi   +3 more
openaire   +2 more sources

The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ

open access: yesAdvanced Science, EarlyView.
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi   +6 more
wiley   +1 more source

From Intelligence gathering to Cyber Threat Detection [PDF]

open access: yesRomanian Intelligence Studies Review, 2023
Intelligence plays a key role in the detection and neutralisation of threat actors in cyberspace, particularly when dealing with advanced ones. However, the relationship between intelligence and the final detection capabilities is not well–defined in ...
Antonio VILLALON-HUERTA   +2 more
doaj  

Cerebral Small Vessel Disease in Immune‐Mediated Thrombotic Thrombocytopenic Purpura Patients During the Acute Phase and Disease Remission

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Immune‐mediated thrombotic thrombocytopenic purpura (iTTP) is a life‐threatening thrombotic microangiopathy characterized by acute neurological manifestations and long‐term sequelae related to microvascular brain injury. Cerebral small vessel disease (cSVD), detectable on MRI through lacunes, microbleeds, white matter hyperintensities, and ...
Addolorata Truma   +13 more
wiley   +1 more source

Dark Higgs-strahlung at Belle II: a distinctive dark sector signature with displaced vertices and missing energy

open access: yesJournal of High Energy Physics
Dark photons with kinetic mixing are compelling mediators for the interactions between dark matter and Standard Model particles. While most experimental searches focus on fully visible or fully invisible decays of dark photons, we explore processes that ...
Francesca Acanfora, Felix Kahlhoefer
doaj   +1 more source

Bottom-quark effects in Higgs production at intermediate transverse momentum

open access: yesJournal of High Energy Physics, 2018
We provide a precise description of the Higgs boson transverse momentum distribution including top and bottom quark contributions, that is valid for transverse momenta in the range m b  ≲ p ⊥ ≲ m t , where m b and m t are the bottom and top quark masses.
Fabrizio Caola   +5 more
doaj   +1 more source

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