Results 181 to 190 of about 63,068 (259)
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa +7 more
wiley +1 more source
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear +7 more
wiley +1 more source
Exome Sequencing in Prenatally Diagnosed Isolated Neural Tube Defects: A Subtype‐Specific Analysis
ABSTRACT Objective To explore potential genetic contributors across different subtypes of isolated neural tube defects (NTDs) ‐ acrania–exencephaly–anencephaly sequence (AEAS), spinal dysraphism, and encephalocele ‐ using exome sequencing (ES) in a prenatal cohort, with the goal of gaining insight into the molecular diversity underlying these distinct ...
Adi Botvinik +9 more
wiley +1 more source
The increasing demand for sustainable food production requires innovative solutions that balance productivity, resource efficiency, and environmental impact. Vertical Farming Systems (VFSs) offer a promising approach; however, their high energy consumption remains challenging.
Alessio Dessì +11 more
wiley +1 more source
Major staple crops are often introduced and cultivated in monocultures. Yams are staple crops native to the majority of low‐ and middle‐income countries and can provide an alternative to introduced staple crops. We showed that lesser yams cultivated together with teak trees (planted at the border of the farm) are more profitable than lesser yam ...
Budiadi +5 more
wiley +1 more source
For generations, Mediterranean communities have used Lamiaceae or Labiatae plants like rosemary, thyme or mint to care for their health and to enrich their food. By bringing together dispersed knowledge from across the Mediterranean region, our review revealed the continuing relevance of Lamiaceae while also compiling past uses that may hold future ...
Fuencisla Cáceres +3 more
wiley +1 more source
Past, present and future of local crop evolution
Promoting agrobiodiversity is a promising strategy for mitigating the negative effects of climate change on global food security. We highlight the central role evolutionary processes play in harnessing the potential of local crops by integrating genomics, archaeology, ethnobotany and traditional ecological knowledge (TEK).
Nataly Allasi Canales +6 more
wiley +1 more source
Climate change and the growing demand for renewable energy are putting increasing pressure on land, as food production and solar power generation often compete for the same areas. In this study, we assessed which temperate‐region crops are best suited for agrivoltaics, a technology combining farming and solar electricity production on the same land. We
Salome Hauger +6 more
wiley +1 more source
Weeds in a changing climate: Competitors or service plants?
Reducing herbicide use and preparing agroecosystems for climate change are two top priorities on the global policy agenda. Here, we explore whether these two challenges can be tackled simultaneously. While weeds are generally considered a threat to crop production, we show that weeds can help overcome climate change challenges in agroecosystems ...
Marie J. Zwetsloot +12 more
wiley +1 more source
There is an increasing risk of drought and salinisation of soil and groundwater globally, including in Pacific Island countries such as Tonga. Irrigating crops with slightly saline water, such as that produced by emerging desalination technologies, could help to alleviate droughts.
Harry Myrans +9 more
wiley +1 more source

