Results 41 to 50 of about 52,517 (177)

Temporal and seasonal trends of bovine tuberculosis in the Irish cattle population (2008–2024)

open access: yesVeterinary Record, EarlyView.
Abstract Background Bovine tuberculosis (bTB) has substantial impacts on the Irish cattle industry. Between 2016 and 2024, its burden increased in Irish cattle. As an initial step towards understanding drivers of this increase, we explore long‐term trends in measures of bTB burden and cattle demographics in Ireland. Methods Using data from 2008 to 2024,
Jamie M. Madden   +8 more
wiley   +1 more source

Tuberculin-Specific T Cells Are Reduced in Active Pulmonary Tuberculosis Compared to LTBI or Status Post BCG Vaccination

open access: yes, 2011
Functional characteristics of tuberculosis (TB)-specific CD4 T cells were studied in clinically active pulmonary TB (n = 21) and high TB exposure including LTBI (n = 17).
Laurel Nomura   +25 more
core   +2 more sources

Tuberculin PPD Potency Assays in Naturally Infected Tuberculous Cattle as a Quality Control Measure in the Irish Bovine Tuberculosis Eradication Programme

open access: yesFrontiers in Veterinary Science, 2019
The Irish Bovine Tuberculosis (bTB) eradication programme operates under national legislation and fulfills OIE and EU trade requirements. Tuberculin purified protein derivative (PPD), a preparation obtained from the heat-treated products of growth and ...
Anthony Duignan   +3 more
doaj   +1 more source

Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non‐Irritative Concentrations

open access: yesAllergy, EarlyView.
ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud   +14 more
wiley   +1 more source

α‐Synuclein strain homogeneity in multiple system atrophy subtypes

open access: yesBrain Pathology, EarlyView.
Two different subtypes of multiple system atrophy are recognized: MSA‐C and MSA‐P. In this manuscript, Lau et al. investigate whether MSA‐C and MSA‐P are caused by different strains of α‐synuclein aggregates. By performing conformational fingerprinting experiments as well as in vitro and in vivo seeding assays, their findings suggest that both MSA‐C ...
Heather H. C. Lau   +10 more
wiley   +1 more source

More on search for causes of sensitization to tuberculin PPD for mammals in cattle [PDF]

open access: yes, 2021
Despite the large number of papers dealing with the description of proposed methods for bovine tuberculosis diagnosis and mechanisms of non-specific reaction development in diseased and healthy animals, various aspects require further study.
P. S. Huseynova, M. O. Baratov
core   +1 more source

Utility of newer technologies for the diagnosis of active and latent tuberculosis [PDF]

open access: yes, 2009
Includes bibliographical references (leaves 91-109).Since the 1800s the tuberculin skin test (TST) has been the only available test for latent tuberculosis (LTBI). Recently, interferon-gamma release assays (IGRAs) have been developed which are based upon
Cashmore, Tamaryn Jane   +1 more
core   +1 more source

Diagnostic value of immunological skin tests in children with tuberculosis

open access: yesТуберкулез и болезни лёгких, 2015
The paper gives the results of an analysis of intracutaneous Mantoux tuberculin tests with 2 TU, 1 TU, 0.1 TU, and 0.01 TU PPD-L and intracutaneous Diaskintest using recombinant tuberculosis allergen in the standard dilution in 63 children with ...
A. G. Smetanin   +2 more
doaj   +1 more source

Cholinergic inputs to motoneurons in the spinal cord augment focal muscle spasticity in rodents

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Cholinergic premotor inputs to motoneurons support high levels of motor output when required. However, the possible role of these inputs in pathologically elevated muscle tone has not been characterised. To address this, we examined the modulatory effect of spinal acetylcholine (ACh) on experimental spastic paralysis ...
Patrik Meglić   +10 more
wiley   +1 more source

Exploring the Fate of Cattle Herds With Inconclusive Reactors to the Tuberculin Skin Test

open access: yesFrontiers in Veterinary Science, 2018
Bovine tuberculosis (TB) is an important animal health issue in many parts of the world. In England and Wales, the primary test to detect infected animals is the single intradermal comparative cervical tuberculin test, which compares immunological ...
Lucy A. Brunton   +4 more
doaj   +1 more source

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