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Type I interferons in tuberculosis: Foe and occasionally friend [PDF]
Journal of Experimental Medicine, 2018 Tuberculosis remains one of the leading causes of mortality worldwide, and, despite its clinical significance, there are still significant gaps in our understanding of pathogenic and protective mechanisms triggered by Mycobacterium tuberculosis infection.
Mayer-Barber, K +3 more
core +2 more sources
An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
Nature, 2010 Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis, is a major cause of morbidity and mortality worldwide. Efforts to control it are hampered by difficulties with diagnosis, prevention and treatment.
Christine M Graham, Zhaohui Xu, Tolu Oni
exaly +2 more sources
Whole genome sequencing of Mycobacterium tuberculosis reveals slow growth and low mutation rates during latent infections in humans [PDF]
, 2014 Very little is known about the growth and mutation rates of Mycobacterium tuberculosis during latent infection in humans. However, studies in rhesus macaques have suggested that latent infections have mutation rates that are higher than that observed ...
Alland, David +9 more
core +28 more sources
Immune evasion and provocation by Mycobacterium tuberculosis
Nature Reviews Microbiology, 2022 Mycobacterium tuberculosis, the causative agent of tuberculosis, has infected humans for millennia. M. tuberculosis is well adapted to establish infection, persist in the face of the host immune response and be transmitted to uninfected individuals.
P. Chandra +2 more
semanticscholar +1 more source
Difficult case of differential diagnosis of partial lung atelectasis. Case report
Терапевтический архив, 2023 In December 2018 the patient over 60 years old sought medical help with complaints of persistent cough. Based on computed tomography data there were identified the sings (symptoms) of right lung lower lobe atelectasis.
Olga M. Gordeeva +6 more
doaj +1 more source
Journal of Immunology Research, 2022 Objective. Multidrug-resistant tuberculosis (MDR-TB) causes persistent infection and challenges tuberculosis control worldwide. T cell-mediated immunity plays a critical role in controlling Mycobacterium tuberculosis (Mtb) infection, and therefore ...
Peijun Tang +17 more
doaj +1 more source
TBDLNet: a network for classifying multidrug-resistant and drug-sensitive tuberculosis [PDF]
Engineering Reports (2023), 2023 This paper proposes applying a novel deep-learning model, TBDLNet, to recognize CT images to classify multidrug-resistant and drug-sensitive tuberculosis automatically. The pre-trained ResNet50 is selected to extract features. Three randomized neural networks are used to alleviate the overfitting problem.
arxiv +1 more source
Possibilities of non-invasive diagnosis of fibrotic phenotype of interstitial lung diseases
Терапевтический архив, 2023 Progressive pulmonary fibrosis is a major problem in respiratory medicine. Currently, there are no reliable biomarkers for early diagnosis of progressive pulmonary fibrosis, which leads to delayed diagnosis. Aim.
Evgeniy I. Shchepikhin +5 more
doaj +1 more source
Epidemiology of childhood tuberculosis after ceasing universal Bacillus Calmette–Guérin vaccination
Scientific Reports, 2021 Universal Bacillus Calmette–Guérin (BCG) vaccination is recommended in countries with high tuberculosis (TB) burden. Nevertheless, several countries have ceased universal BCG vaccination over the past 40 years, with scarce comparative epidemiological ...
Sayori Kobayashi +4 more
doaj +1 more source
Вестник хирургии имени И.И. Грекова, 2021 An observation from practice is given – surgical treatment of a patient with advanced tuberculosis of a single lung and a pronounced lung displacement. Patient A., 47 years old, after 3 months from the left pneumonectomy for fibrocavernous tuberculosis ...
R. V. Tarasov +5 more
doaj +1 more source