Results 1 to 10 of about 1,198,187 (379)

Whole genome sequencing of Mycobacterium tuberculosis reveals slow growth and low mutation rates during latent infections in humans [PDF]

, 2014
Very little is known about the growth and mutation rates of Mycobacterium tuberculosis during latent infection in humans. However, studies in rhesus macaques have suggested that latent infections have mutation rates that are higher than that observed ...
Alland, David, Arcus, Vickery L., Colangeli, Roberto, Coley, Kathy, Cursons, Raymond T., Karalus, Noel, Kim, Soyeon, Manning, Shannon D., Marchiano, Emily, Ruthe, Ali   +9 more
core   +32 more sources

Difficult case of differential diagnosis of partial lung atelectasis. Case report

Терапевтический архив, 2023
In December 2018 the patient over 60 years old sought medical help with complaints of persistent cough. Based on computed tomography data there were identified the sings (symptoms) of right lung lower lobe atelectasis.
Olga M. Gordeeva, Anna D. Egorova, Yana O. Chesalina, Evgeniy M. Gretcov, Lyudmila A. Semenova, Natalia L. Karpina, Ilya V. Sivokozov   +6 more
doaj   +1 more source

Autologous Cytokine-Induced Killer Cell Immunotherapy Enhances Chemotherapy Efficacy against Multidrug-Resistant Tuberculosis

Journal of Immunology Research, 2022
Objective. Multidrug-resistant tuberculosis (MDR-TB) causes persistent infection and challenges tuberculosis control worldwide. T cell-mediated immunity plays a critical role in controlling Mycobacterium tuberculosis (Mtb) infection, and therefore ...
Peijun Tang, Xingnian Chen, Junchi Xu, Yunlong Hu, Zhijian Ye, Xiafang Wang, Yumei Xiao, Xinghua Shen, Jianping Zhang, Yanjun Feng, Cuilin Shi, Xin Yu, Lixian Yi, Xinchun Chen, Binfeng Lu, Ping Xu, Zhongwen Sun, Meiying Wu   +17 more
doaj   +1 more source

Effect of CFP-10/ESAT-6 secretory proteins on long-term non-specific immunological memory in mouse macrophages

Медицинская иммунология, 2023
Innate immune cells (monocytes/macrophages, NK) can also develop immune memory, which means that these cells are trained after their first encounter with pathogens so that they exhibit a nonspecific immunological response to the same or another pathogen.
А. P. Lykov, S. N. Belogorodtsev, Е. К. Nemkova, А. Vetlugina, Т. М. Terekhova, Ya. Sh. Schwartz   +5 more
doaj   +1 more source

Tuberculosis and COVID-19 in Children and Adolescents. Two Waves of the Pandemic: Experiences and Conclusions

Туберкулез и болезни лёгких, 2022
The objective of the study: to investigate diagnostics, course and outcomes of COVID-19 in children and adolescents with tuberculosis in relation to the epidemic control activities.Subjects and Methods: during the pandemic of coronavirus infection (the ...
E. S. Ovsyankina, L. V. Panova, M. F. Gubkina, A. E. Ergeshov, I. Yu. Petrakova, E. A. Krushinskaya   +5 more
doaj   +1 more source

TBDLNet: a network for classifying multidrug-resistant and drug-sensitive tuberculosis [PDF]

Engineering Reports (2023), 2023
This paper proposes applying a novel deep-learning model, TBDLNet, to recognize CT images to classify multidrug-resistant and drug-sensitive tuberculosis automatically. The pre-trained ResNet50 is selected to extract features. Three randomized neural networks are used to alleviate the overfitting problem.
arxiv   +1 more source

Acceptability, feasibility, and likelihood of stakeholders implementing the novel BPaL regimen to treat extensively drug-resistant tuberculosis patients

BMC Public Health, 2021
Background BPaL, a 6 month oral regimen composed of bedaquiline, pretomanid, and linezolid for treating extensively drug-resistant tuberculosis (XDR-TB) is a potential alternative for at least 20 months of individualized treatment regimens (ITR). The ITR
S. E. J. van de Berg, P. T. Pelzer, A. J. van der Land, E. Abdrakhmanova, A. Muhammad Ozi, M. Arias, S. Cook-Scalise, G. Dravniece, A. Gebhard, S. Juneja, R. Handayani, D. Kappel, M. Kimerling, I. Koppelaar, S. Malhotra, B. Myrzaliev, B. Nsa, J. Sugiharto, N. Engel, C. Mulder, S. van den Hof   +20 more
doaj   +1 more source

Pathomorphosis of Extrapulmonary Tuberculosis in Children [PDF]

, 2016
Aim. To study clinical and epidemiological aspects of pathomorphosis of extrapulmonary tuberculosis clinical forms.Materials and Methods. Retrospective analysis of 138 case histories in children aged to 15 years, obtaining extrapulmonary tuberculosis ...
Mykolyshyn, L. (Lidia), Piskur, Z. (Zoriana)   +1 more
core   +2 more sources

Drug-Resistant Tuberculosis--Current Dilemmas, Unanswered Questions, Challenges and Priority Needs [PDF]

, 2012
Tuberculosis was declared a global emergency by the World Health Organization (WHO) in 1993. Following the declaration and the promotion in 1995 of directly observed treatment short course (DOTS), a cost-effective strategy to contain the tuberculosis ...
Abubakar, Ibrahim, Atun, Rifat, Chakaya, Jeremiah, Cox, Helen, Ditiu, Lucica, Ford, Nathan, Grobusch, Martin, Hoelscher, Michael, Lawn, Stephen D., Maeurer, Markus, Marais, Ben, Mchugh, Timothy D., McNerney, Ruth, Memish, Ziad, Migliori, Giovanni-Battista, Mwaba, Peter, O'Grady, Justin, Pletschette, Michel, Ramsay, Andrew, Raviglione, Mario, Schito, Marco, Squire, S. Bertel, Swaminathan, Soumya, Zumla, Alimuddin   +23 more
core   +1 more source

Diabetes and tuberculosis: the impact of the diabetes epidemic on tuberculosis incidence. [PDF]

, 2007
BACKGROUND: Tuberculosis (TB) remains a major cause of mortality in developing countries, and in these countries diabetes prevalence is increasing rapidly. Diabetes increases the risk of TB.
Dye, Chirstopher, Forouhi, Nita G., Lauer, Jeremy A., Roglic, Gojka, Stevenson, Catherine R., Unwin, Nigel, Williams, Brian G.   +6 more
core   +2 more sources