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Although the worldwide incidence of tuberculosis has been slowly decreasing, the global disease burden remains substantial (∼9 million cases and ∼1·5 million deaths in 2013), and tuberculosis incidence and drug resistance are rising in some parts of the world such as Africa.
Keertan, Dheda +2 more
+10 more sources
Tuberculosis remains a serious health problem worldwide, particularly affecting the poorest in both high-income and developing countries. It was declared a global emergency by the World Health Organization in 1993. Central nervous system (CNS) tuberculosis is caused by mycobacteria belonging to the Mycobacterium tuberculosis complex, and is acquired ...
openaire +5 more sources
Mycobacterium tuberculosis type VII secretion system effectors differentially impact the ESCRT endomembrane damage response [PDF]
Mycobacterium tuberculosis causes tuberculosis, which kills more people than any other infection. M. tuberculosis grows in macrophages, cells that specialize in engulfing and degrading microorganisms.
Hanson, Phyllis I +7 more
core +2 more sources
Association Between Smoking and Tuberculosis Infection: A Population Survey in a High Tuberculosis Incidence Area [PDF]
Associations between smoking and tuberculosis disease including death from tuberculosis have been reported, but there are few reports on the influence of smoking on the risk of developing Mycobacterium tuberculosis infection. The aim of this study was to
Bateman, E.D +7 more
core +11 more sources
An observation from practice is given – surgical treatment of a patient with advanced tuberculosis of a single lung and a pronounced lung displacement. Patient A., 47 years old, after 3 months from the left pneumonectomy for fibrocavernous tuberculosis ...
R. V. Tarasov +5 more
doaj +1 more source
The detection of airborne transmission of tuberculosis from HIV-infected patients, using an in vivo air sampling model [PDF]
Background. Nosocomial transmission of tuberculosis remains an important public health problem. We created an in vivo air sampling model to study airborne transmission of tuberculosis from patients coinfected with human immunodeficiency virus (HIV) and ...
A. Gonzalez +40 more
core +2 more sources
Background BPaL, a 6 month oral regimen composed of bedaquiline, pretomanid, and linezolid for treating extensively drug-resistant tuberculosis (XDR-TB) is a potential alternative for at least 20 months of individualized treatment regimens (ITR). The ITR
S. E. J. van de Berg +20 more
doaj +1 more source
Possibilities of non-invasive diagnosis of fibrotic phenotype of interstitial lung diseases
Progressive pulmonary fibrosis is a major problem in respiratory medicine. Currently, there are no reliable biomarkers for early diagnosis of progressive pulmonary fibrosis, which leads to delayed diagnosis. Aim.
Evgeniy I. Shchepikhin +5 more
doaj +1 more source
▪ Abstract Tuberculosis is an infectious disease caused by bacteria in the Mycobacterium tuberculosis complex. Of these, the most common species to infect humans is M. tuberculosis. The TB bacillus is an extremely successful human pathogen, infecting two billion persons worldwide; an estimated 2 to 3 million people die from tuberculosis each year.
Parvathi, Tiruviluamala, Lee B, Reichman
openaire +2 more sources
Household screening and multidrug-resistant tuberculosis [PDF]
Of the estimated half a million people who develop multidrug resistant (MDR) tuberculosis each year, less than 7% are diagnosed and only 1 in 5 of these have access to eff ective treatment.1 To control this epidemic, dramatically increased efforts are ...
Becerra +9 more
core +2 more sources

