Results 121 to 130 of about 828,953 (227)

Streptococcus pneumoniae HtrA is a dynamic and monomeric virulence factor capable of forming larger oligomeric complexes

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract High‐temperature requirement A (HtrA) proteases are a conserved family of serine proteases central to protein quality control and bacterial virulence. While Gram‐negative and human HtrAs are structurally well studied, Gram‐positive homologs remain essentially uncharacterized.
Eunjeong Lee   +14 more
wiley   +1 more source

Novel Respiratory Disease Diagnosis Tool: Development of an Au‐ReS2‐Functionalized Extended‐gate Field‐Effect Transistor‐Type Aptasensor for Simultaneous Detection of Granzyme B and Perforin

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
The simultaneous GzmB and PRF‐targeting EG‐FET‐type biosensor is developed for the diagnosis of respiratory diseases. The biosensor achieves femtomolar‐level detection of targets in human serum and reflects bronchial function according to cytotoxic immune activity in COPD patients. Therefore, the introduced system is proposed as an accurate, rapid, and
Seokho Jung   +13 more
wiley   +1 more source

Knowledge, Attitudes and Practices Regarding Livestock Diseases Among Residents of East Gojjam Zone, Amhara Region, Ethiopia

open access: yesVeterinary Medicine and Science, Volume 12, Issue 1, January 2026.
This study reveals gaps in livestock owners’ knowledge and practices regarding disease prevention and control in East Gojjam Zone, Ethiopia, highlighting the need for strengthened veterinary extension services and community education to improve animal health management.
Liuel Yizengaw   +7 more
wiley   +1 more source

Prevalence of bovine tuberculosis in the Aksu Region of Xinjiang, China, between 1985 and 2016

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia
Prevalence of bovine tuberculosis infection in cattle in Aksu Prefecture determined by intradermal tuberculin skin test (TST), between 1985 and 2016. Cattle were analyzed according to region, feeding pattern, herds and age. A total of 890,009 cattle were
Y.H. Liu   +6 more
doaj   +1 more source

Advances in Microbial Diagnostics: Machine Learning and Nanotechnology for Zoonotic Disease Control

open access: yesWIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 1, January/February 2026.
This review highlights how integrating machine learning with nanotechnology enables enhanced diagnostics, personalized treatments, and the prediction of outbreaks for zoonotic diseases, offering a unified framework to advance global health. ABSTRACT Zoonotic diseases pose significant global health threats, with microbial pathogens, including bacteria ...
Narges Lotfalizadeh   +8 more
wiley   +1 more source

Epidemiological Dynamics of a Visually Apparent Disease: Camera Trapping and Machine‐Learning Applied to Rumpwear in the Common Brushtail Possum

open access: yesIntegrative Zoology, Volume 21, Issue 1, Page 116-128, January 2026.
Visually apparent diseases are valuable for investigating and monitoring the occurrence and prevalence of pathogens in wildlife populations through passive monitoring methods like camera trapping. Rumpwear is characterized by visible signs of hair breakage and damage on the lumbosacral region of common brushtail possums.
Elise M. Ringwaldt   +3 more
wiley   +1 more source

Isolamento de cepas de Mycobacterium avium em búfalos abatidos para consumo

open access: yesRevista de Saúde Pública
Duas cepas micobacterianas, isoladas no parênquima pulmonar e linfonodo apical de búfalos abatidos para consumo, procedentes de criatórios localizados na Ilha de Marajó (PA) e submetidas à identificação segundo ensaios recomendados para o gênero ...
José de Arimatéa Freitas   +3 more
doaj  

Single‐Nucleus Transcriptomics Uncovers Xaf1‐Driven PANoptosis as a Therapeutic Target in Aminoglycoside‐Induced Hearing Loss

open access: yesCell Proliferation, Volume 59, Issue 1, January 2026.
Neomycin induces increased expression of Xaf1 in cochlear HCs, triggering PANoptosis, which encompasses pyroptosis, apoptosis and necroptosis (left). Targeted Xaf1 knockdown in HCs through gene therapy can significantly inhibit the occurrence of PANoptosis in HCs (right).
Xinlin Wang   +10 more
wiley   +1 more source

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