Results 91 to 100 of about 127,769 (266)

Clinical efficacy, radiographic and safety findings through 2 years of golimumab treatment in patients with active psoriatic arthritis: results from a long-term extension of the randomised, placebo-controlled GO-REVEAL study [PDF]

, 2013
Objectives: To assess long-term golimumab efficacy/safety in patients with active psoriatic arthritis (PsA).<p></p> Methods Adult PsA patients (≥3 swollen, ≥3 tender joints, active psoriasis) were randomly assigned to ...
Beutler, A., Gladman, D.D., Kavanaugh, A., Krueger, G.G., Mack, M., McInnes, I.B., Mease, P.J., Mudivarthy, S., van der Heijde, D., Xu, W., Xu, Z.   +10 more
core   +1 more source

Potential Biomarkers for Disease Stratification and Prognosis Prediction in Pediatric Asthma: LCN2, sST2 and FGF21

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers.
Xu Yang, Hai Wang, Yong‐Zheng Zhang, Yan‐Yan Chen, Xin‐Xin Xing, Yi‐Cheng Ding   +5 more
wiley   +1 more source

Safety of treatment regimens in multiple drug resistant tuberculosis patients compiled as per the new WHO recommendations as of 2019

Туберкулез и болезни лёгких, 2020
The objective: safety assessment of chemotherapy regimens compiled in accordance with the recommendations of World Health Organization (WHO), 2019, in patients with multiple drug resistant tuberculosis (MDR) in clinical practice settings.Subjects ...
D. A. Ivanova, S. E. Borisov, O. V. Rodina, A. V. Filippov, T. N. Ivanushkina, N. V. Litvinova   +5 more
doaj   +1 more source

Research needs for an improved primary care response to chronic non-communicable diseases in Africa. [PDF]

, 2010
With non-communicable diseases (NCDs) projected to become leading causes of morbidity and mortality in developing countries, research is needed to improve the primary care response, especially in sub-Saharan Africa.
Abegunde, Adeyi, Anonymous, Bach, Beaglehole, Chan, Coovadia, Council for International Organisations of Medical Sciences, Craig, Daar, Harries, Harries, Kumwenda, Maher, Maher, Maher, Ministry of Health of Government of Uganda, Ministry of Health of Government of Uganda, Ooms, Sanders, Setel, Sewankambo, Suhrcke, Tollman, United Kingdom Department for International Development, WHO, WHO, WHO, Wilkinson, World Diabetes Foundation   +29 more
core   +1 more source

Pan immune inflammation value improves MELD 3.0 for mortality prediction in critically ill cirrhotic patients

Scientific Reports
Liver cirrhosis poses a significant global health burden, with over 100 million cases worldwide and 2 million annual deaths. Despite advances in prognostic tools like MELD 3.0, their performance remains suboptimal. The pan-immune-inflammation value (PIV),
Ling Zhu, Peibo Li, Chengdong You
doaj   +1 more source

Rates and Causes of Death in Chiradzulu District, Malawi, 2008: A Key Informant Study [PDF]

, 2010
In September 2008, we measured all-cause mortality in Chiradzulu District, Malawi (population 291 000) over a 60-day retrospective period, using capture-recapture analysis of three lists of deaths provided by (i) key community informants, (ii) graveyard ...
Adjuik, Baiden, Doctor, Fienberg, Hosegood, International Working Group for Disease Monitoring and Forecasting, Jahn, Mathers, Roberts, Setel, World Health Organization   +10 more
core   +2 more sources

Characterisation of bacteria‐induced colitis and its modulation by probiotics in naked mole rats: a new mammalian model for acute inflammatory disease

The Journal of Pathology, EarlyView.
Abstract Enteropathogenic bacteria are a major cause of morbidity and mortality globally. While mouse models have been indispensable in advancing our understanding of infectious enteric diseases, key differences in intestinal microbiota and immunobiology between mice and humans underscore the need for alternative mammalian models that better ...
Daniel W. Hart, Aik Seng Ng, Patrycja Gazińska, Robert Goldin, Purva Gopal, Nicolize O'Dell, Ahmad Zargar, Lior Pytowski, Shamir Montazid, Chiara Bardella, James E. East, Ian P. Tomlinson, Nadine Koch, Nigel C. Bennett, Shazia Irshad   +14 more
wiley   +1 more source

Cardiovascular Mortality among Tuberculosis Patients

Abstract Introduction: Tuberculosis and cardiovascular disease (CVD) pose significant health challenges in developing countries. Research suggests a connection between tuberculosis infections and the development of CVD. The immune response to Mycobacterium tuberculosis, driven by monocytes, macrophages, lymphocytes, and cytokines, also plays a ...
Bheesham Kingrani, Amer Hayat Khan, Sabariah Noor Harun, Ali Qureshi, Irfhan Ali Hyder Ali, Mahmood Basil Al-Rawi, Irfanullah Khan   +6 more
openaire   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Massive primary pulmonary artery rhabomyosarcoma: A case report

Romanian Journal of Internal Medicine
Pulmonary artery sarcomas (PAS) are rare tumours causing an insidiously progressive obstruction of the pulmonary circulation. The clinical presentation is often indistinguishable from chronic thromboembolic pulmonary hypertension (CTEPH).
Rashidi Farid, Bilehjani Eissa, Mousavi-Aghdas Seyed Ali, Parvizi Rezayat   +3 more
doaj   +1 more source