Results 131 to 140 of about 127,769 (266)

Safety of upadacitinib in atopic dermatitis in randomized clinical trials across 6 years

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The current study found no evidence of cumulative increased safety risks with upadacitinib 15 or 30 mg for up to 6 years and over 9000 patient‐years of safety data in adults and adolescents. There were low rates of adjudicated major adverse cardiovascular events, adjudicated thromboembolic events and malignancies. Abstract Background Atopic dermatitis (
Christopher G. Bunick, Alan D. Irvine, Jonathan I. Silverberg, Emma Guttman‐Yassky, Mona Shahriari, Xinghua Gao, Stephan Weidinger, Norito Katoh, Namita Vigna, Deanne M. Dilley, Elvira D'Andrea, Henrique D. Teixeira, Andrew M. Platt, Gweneth F. Levy   +13 more
wiley   +1 more source

French guidelines on systemic treatments for moderate‐to‐severe psoriasis in adults: Update 2025

Journal of the European Academy of Dermatology and Venereology, EarlyView.
New 2025 French guidelines update psoriasis management with revised algorithms integrating recent systemic therapies. They recommend methotrexate, adalimumab or ustekinumab as first‐line treatments and provide guidance for special psoriasis forms, comorbidities, pregnancy and long‐term management.
Marie Masson Regnault, Emilie Brenaut, Marie‐Emeline Marniquet, Carla Berthault, Lea Canoen, Clarisse Marcombes, Audrey Melin, Raphaël Ouakrat, Julie Charles, Stephane Mouret, Olivier Potie, Laetitia Penso, Laura Pina Vegas, Guillaume Larid, Marine Roux, Colombe Bougeard, Sandy Sylvain, Clara Labonne, Tania Randriamiarana, Da Hee Pitaud, Floriane Etheve, Jeremy Gottlieb, Laurie Gouillon, Marine Chastagner, Emilie Sbidian, Hélène Aubert, on behalf of the Psoriasis Research Group of the French Society of Dermatology (Groupe de Recherche sur le Psoriasis de la Société Française de Dermatologie), Hélène Aubert, Marie Masson Regnault, Emilie Brenaut, Emilie Sbidian, Laura Pina Vegas, Laetitia Penso, Jeremy Gottlieb, Marine Roux, Clara Labonne, Tania Randriamiarana, Floriane Etheve, Da Hee Pitaud, Marie‐Emeline Marniquet, Carla Berthault, Clarisse Marcombes, Audrey Melin, Colombe Bougeard, Julie Charles, Olivier Potie, Léa Canoen, Laurie Gouillon, Marine Chastagner, Sandy Sylvain, Guillaume Larid, Raphaël Ouakrat   +51 more
wiley   +1 more source

Health and nutrition: emerging and reemerging issues in developing countries [PDF]

CONTENTS: Brief 1. Overview / Rafael Flores Brief 2. The Global Burden of Disease / Alan D. Lopez Brief 3. HIV/AIDS / Anthony Barnett and Gabriel Rugalema Brief 4. Malaria / Andrea Egan Brief 5. Tuberculosis / Ariel Pablos-Mendez Brief 6.
Flores, Rafael, ed., Gillespie, Stuart, ed.   +1 more
core  

The “Reducing Inflammation for Greater Health Trial (RIGHT)” Study—Concept, Rationale, and Design

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT The Reducing Inflammation for Greater Health Trial's (RIGHT) study is a single‐center, randomized, double‐blind, placebo‐controlled trial designed to test whether clazkizumab, an interleukin‐6 (IL‐6) inhibitor, can improve or slow decline in physical, cognitive, and vascular function in older adults, when compared to a placebo.
Sebastian E. Sattui, Marnie Bertolet, Daniel E. Forman, Michelle E. Danielson, Shanshan Yao, Oscar L. Lopez, Nancy W. Glynn, Neelesh K. Nadkarni, Akira Sekikawa, Tullia C. Bruno, Toren Finkel, Anne B. Newman   +11 more
wiley   +1 more source

The Effect of Vitamin D3 Supplementation on the Risk of Falls in a General Population—The Finnish Vitamin D Trial

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background The impact of vitamin D on fall incidence remains controversial. We studied the effect of 5 years of vitamin D3 supplementation on the risk of falls in a double‐blind, placebo‐controlled randomized trial with generally healthy, community‐dwelling men and women in Finland.
Toni Rikkonen, Sari Hantunen, Heikki Kröger, Christel Lamberg‐Allardt, JoAnn E. Manson, Tarja Nurmi, Marjo Tuppurainen, Ari Voutilainen, Tomi‐Pekka Tuomainen, Jyrki K. Virtanen   +9 more
wiley   +1 more source

Association of prior tuberculosis with cardiovascular status in perinatally HIV-1-infected adolescents

Open Heart
Background Whether, and how, co-occurring HIV-1 infection (HIV) and tuberculosis (TB) impact cardiovascular status, especially in adolescents with perinatally acquired HIV (APHIV), have not been examined. We hypothesised that APHIV with previous TB disease have worse cardiac efficiency than APHIV without TB, which ...
Itai M Magodoro, Carlos Eduardo Guerrero-Chalela, Emma Carkeek, Nana Akua Asafu-Agyei, Nomawethu Jele, Lisa J Frigati, Landon Myer, Jennifer Jao, Mpiko Ntsekhe, Katalin A Wilkinson, Robert J Wilkinson, Heather Zar, Ntobeko Ntusi   +12 more
openaire   +4 more sources

Excessive Daytime Sleepiness, but Not Insomnia Is Associated With Dyslipidaemia in Patients With Obstructive Sleep Apnoea Participating in ESADA

Journal of Sleep Research, EarlyView.
ABSTRACT Excessive daytime sleepiness (EDS) as well as insomnia have been associated with a higher risk for cardiovascular disease in patients with obstructive sleep apnoea (OSA). The link is not fully understood but may involve dyslipidaemia. The aim of the study was to analyse if the EDS and insomnia phenotypes were associated with deranged serum ...
Andras Bikov, Sebastien Bailly, Ulla Anttalainen, Tarja Saaresranta, Ozen K. Basoglu, Sophia Schiza, Izolde Bouloukaki, Pawel Sliwinski, Athanasia Pataka, Dries Testelmans, Francesco Fanfulla, Haralampos Gouveris, Ludger Grote, Stefan Mihaicuta, the ESADA collaborators, P. Steiropoulos, J. Verbraecken, E. Petiet, Georgia Trakada, I. Fietze, T. Penzel, Ondrej Ludka, I. Bouloukaki, S. Schiza, W. T. McNicholas, S. Ryan, R. L. Riha, J. A. Kvamme, L. Grote, J. Hedner, D. Zou, Katrien Hertegonne, Dirk Pevernagie, S. Bailly, J. L. Pépin, R. Tamisier, H. Hein, O. K. Basoglu, M. S. Tasbakan, P. Joppa, R. Staats, Dries Testelmans, Alexandros Kalkanis, Haralampos Gouveris, K. Ludwig, C. Lombardi, G. Parati, M. R. Bonsignore, Francesco Fanfulla, M. Petitjean, G. Roisman, M. Drummond, M. van Zeller, W. Randerath, S. Mathes, Z. Dogas, T. Galic, A. Pataka, S. Mihaicuta, U. Anttalainen, T. Saaresranta, P. Sliwinski   +61 more
wiley   +1 more source

The Survival of the Royals

Kyklos, EarlyView.
ABSTRACT We study the effect of royal status—a historically rooted legal privilege enjoyed by hereditary monarchs and their families—on human longevity, a proxy of individuals' health capital. We disentangle the effect of royal status that encompassed serving as heads of state from that of other royal family members and compare it to their contemporary
Alberto Batinti, Joan Costa‐Font, Vasuprada Shandar   +2 more
wiley   +1 more source

Enduring and the horizon of repair: French Caribbean post‐stroke rehabilitation amid health inequity

Medical Anthropology Quarterly, EarlyView.
Abstract Drawing on ethnographic research with patients and therapists in post‐stroke rehabilitation, this article explores how Guadeloupeans strive to exist on their own terms amid postcolonial health inequities, forms of marginalization and institutional disrepair.
Raphaëlle Melissa Rabanes
wiley   +1 more source

Differential trends in the compression of mortality: Assessing the antecedents to current gaps in health expectancy in New Zealand [PDF]

, 2009
Health Expectancies (HEs) for New Zealand show significant differentials between Maori and non-Maori, but also by gender and period. These differentials correlate with findings from both generation and synthetic life-tables relating to New Zealand’s ...
Amey, Ben, Boddington, Bill, Cheung, Jit, Didham, Robert, Pool, Ian   +4 more
core   +1 more source