Results 171 to 180 of about 58,147 (226)

Smoking Promotes AT2 Cell Senescence and Exacerbates Pulmonary Fibrosis by Downregulating POT1 via Integratively Inducing CpG Methylation and MECP2‐Mediated FOXP2 Transcriptional Binding Inhibition

Aging Cell, Volume 24, Issue 10, October 2025.
Smoking is one of the major causes of pulmonary fibrosis (PF), and treatment options for PF are limited. We show that POT1 is decreased in PF patients and mice, especially in smoke exposure, and investigate its contributions to PF progression from protecting AT2 cell senescence to fibrosis. AAV9‐mediated restoration of POT1 prevents PF.
Mengkun Shi, Wei Wang, Posum Wan, Jialun Shi, Huixia Cui, Zhonghan Sun, Xiaofeng Chen, Jingyu Chen, Jiucun Wang, Xiangguang Shi   +9 more
wiley   +1 more source

'Localized' constrictive pericarditis. [PDF]

Eur Heart J Case Rep
Yuan S, Wei M, Li P.
europepmc   +1 more source

A Comparison of AI and Population PK Models to Predict the Concentrations of Antiepileptic Drugs Using Therapeutic Drug Monitoring Records

Clinical and Translational Science, Volume 18, Issue 10, October 2025.
ABSTRACT Population pharmacokinetic (PK) models are commonly used to predict drug concentrations, but artificial intelligence (AI) models have gained interest due to their ability to identify complex patterns without requiring mathematical assumptions. This study compares the predictive performance of AI and population PK models using therapeutic drug ...
Tae Kyu Chung, Howard Lee
wiley   +1 more source

Cardiac MRI in Identifying Myopericarditis Mimicking STEMI in a Patient with HIV: A Case Report. [PDF]

Am J Case Rep
Bharaj IS, Brar A, Mohmand B, Morris M, Yeneneh BT.   +4 more
europepmc   +1 more source

Role of Tie‐2 Axis in Sepsis: A Potential Therapeutic Target

Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.
ABSTRACT The angiopoietins (Angs)–Tie‐2 axis initiates signalling pathways that modulate vascular stability and angiogenesis and plays an important role in a variety of physiological and pathological processes, including inflammation, wound healing and cancer, by regulating endothelial cell proliferation, survival, migration, invasion and/or ...
Jun Feng, Junhui Liu, Xiaoyan Wu, Junshuai Wang   +3 more
wiley   +1 more source

Sensitivity and specificity of Gene Xpert Ultra in extrapulmonary tuberculosis (EPTB). [PDF]

Lung India
Prakash AK, Ramakrishnan GDA.
europepmc   +1 more source

The Association of Periodontal Inflammation and Systemic Health Indicators: A Machine Learning Approach

Journal of Clinical Periodontology, Volume 52, Issue 10, Page 1466-1477, October 2025.
ABSTRACT Aim The relationship between oral and systemic inflammation has profound implications for understanding the broader health impacts of periodontitis. The aim of this study was to (a) explore the association between periodontal inflammation and markers of systemic inflammation and metabolic health, and (b) preliminarily assess periodontal status
Yumeng Yan, Praveen Sharma, Jeanie Suvan, Francesco D'Aiuto   +3 more
wiley   +1 more source

Paradoxical Use of Benralizumab in Reactive Hypereosinophilia from Toxocariasis and Tuberculosis Co-Infection-Case Report and Literature Review. [PDF]

Int J Mol Sci
Bertici NS, Cut TG, Ridichie A, Manzur AR, Bertici RA.   +4 more
europepmc   +1 more source