Results 111 to 120 of about 43,266 (236)

Association of polymorphisms in drug transporter genes (SLCO1B1 and SLC10A1) and anti-tuberculosis drug-induced hepatotoxicity in a Chinese cohort [PDF]

open access: yes, 2015
This study investigated the association between genetic variants in two hepatic uptake transporter genes (SLCO1B1 and SLC10A1) and the risk of anti-tuberculosis drug-induced hepatotoxicity (ATDH) in a Chinese cohort.
Chen, Dafang   +11 more
core   +1 more source

Primary hepatic tuberculosis masquerading as cholangiocarcinoma: A clinical nugget

open access: yesThe Turkish Journal of Gastroenterology, 2019
Cite this article as: Shera IA, Shawl MR, Rajan P, Soni RC. Primary hepatic tuberculosis masquerading as cholangiocarcinoma: A clinical nugget. Turk J Gastroenterol 2019; 30(8): 764-6.
Irfan Ali Shera   +3 more
doaj   +1 more source

A Review of Breath Sensing for Disease Monitoring and Diagnosis: Breathomics, Artificial Intelligence, and Nanomaterials for the Future of Medicine

open access: yesAdvanced Sensor Research, Volume 5, Issue 7, July 2026.
Breathomics is established as a non‐invasive diagnostic strategy by combining volatile organic compound biomarkers, nanomaterial‐based sensor arrays, and AI‐driven classification. Key diseases, sensing materials, and analytical challenges are critically compared, revealing how portable, data‐enabled breath platforms are moving toward clinically useful ...
Anesu Nyabadza   +3 more
wiley   +1 more source

Efficacy and Safety of Subcutaneous Efgartigimod PH20 in Adults With Primary Immune Thrombocytopenia (ADVANCE SC): A Multicenter, Randomized, Double‐Blinded, Placebo‐Controlled, Phase 3 Trial

open access: yesAmerican Journal of Hematology, Volume 101, Issue 7, Page 1494-1506, July 2026.
ABSTRACT Primary autoimmune thrombocytopenia (ITP) is characterized by thrombocytopenia, bleeding, and reduced health‐related quality of life. In the Phase 3 ADVANCE IV study, intravenous efgartigimod induced significant platelet count responses versus placebo in patients with chronic ITP. ADVANCE SC, a Phase 3, multicenter, randomized, double‐blinded,
Nichola Cooper   +546 more
wiley   +1 more source

Glutathione Depletion Exacerbates Hepatic Mycobacterium tuberculosis Infection [PDF]

open access: yes
Extrapulmonary tuberculosis (EPTB) accounts for approximately 17% of all Mycobacterium tuberculosis (M.tb) infections globally. Immunocompromised individuals, such as those with HIV infection or type 2 diabetes mellitus (T2DM), are at an increased risk ...
Kayvan Sasaninia   +10 more
core   +1 more source

Linezolid‐induced lactic acidosis in critically ill patients: A multicentre study of incidence, severity and predictors

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2239-2249, July 2026.
Abstract Introduction Linezolid, a synthetic oxazolidinone for resistant gram‐positive infections, is generally associated with mild adverse effects such as gastrointestinal disturbances, but more serious reactions like lactic acidosis (LA) have also been reported.
Lina Naseralallah   +4 more
wiley   +1 more source

Hepatic tuberculosis in human immunodeficiency virus co-infected adults: a case series of South African adults [PDF]

open access: yes, 2017
Background: Although Mycobacterium tuberculosis (TB) infection may cause extrapulmonary disease in HIV-infected adults, HIV-associated hepatic TB has been poorly characterized. Our objective was to describe hepatic TB in HIV-infected adults.
Gounder, Lilishia   +9 more
core   +1 more source

First Reported Case of Fulminant Weil's Disease in South Khorasan, Eastern Iran: Diagnostic Challenges in a Non‐Endemic Region and Implications for Military Deployment

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Weil's disease should be considered even in non‐endemic regions when compatible clinical findings are accompanied by relevant exposure history. This case is epidemiologically notable as the first documented report from South Khorasan Province, highlighting the diagnostic challenges of leptospirosis in non‐endemic settings and the potential ...
Zohreh Azarkar   +3 more
wiley   +1 more source

Liver toxicity associated with tuberculosis chemotherapy in the REMoxTB study

open access: yesBMC Medicine, 2018
Background Drug-induced liver injury (DILI) is a common complication of tuberculosis treatment. We utilised data from the REMoxTB clinical trial to describe the incidence of predisposing factors and the natural history in patients with liver enzyme ...
Conor Duncan Tweed   +17 more
doaj   +1 more source

Interplay Between Infectious Diseases and the Endocrine System: An Overview and Clinical Insights

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Infectious diseases can disrupt endocrine homeostasis through direct cytopathic injury, autoimmune dysregulation, or pathogen‐derived hormone‐like effects. Viruses and bacteria are the most frequent agents, whereas fungi and parasites contribute less commonly, even remaining clinically relevant, especially in the immunocompromised population.
Francesco Capoccia   +4 more
wiley   +1 more source

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