Results 81 to 90 of about 41,022 (193)
The Journal of Pathology, Volume 268, Issue 4, Page 493-511, April 2026.Abstract Enteropathogenic bacteria are a major cause of morbidity and mortality globally. While mouse models have been indispensable in advancing our understanding of infectious enteric diseases, key differences in intestinal microbiota and immunobiology between mice and humans underscore the need for alternative mammalian models that better ...
Daniel W. Hart +14 more
wiley +1 more source
A 36-Year-Old Moroccan Man Presenting with Widespread Papules and Pustules
Dermatopathology, 2019 Cutaneous manifestations of tuberculosis are uncommon, can be nonspecific, and may demonstrate a wide variety of morphologies, including ulcerative papules, verrucous plaques, or nodules.
Anna Morenz +3 more
doaj +1 more source
Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.ABSTRACT Busulfan is an alkylating agent used in combination with other chemotherapeutic agents and has become a common component of conditioning regimens prior to hematopoietic stem cell transplantation. Busulfan has a very narrow therapeutic index corresponding to the area under the plasma concentration–time curve, with supra‐therapeutic busulfan ...
Colleen Drangines +2 more
wiley +1 more source
مجله دانشگاه علوم پزشکی گرگان, 2014 Background and Objective: Anti tuberculosis drugs therapy is the most effective method for controling the tuberculosis (TB). Early detection and appropriate treatment can prevent the TB-drug resistance.
Khodabakhshi B +4 more
doaj
Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 4, April 2026.ABSTRACT Sex hormone–binding globulin (SHBG) is a sex hormone carrier. We aimed to characterize the role of pregnane X receptor (PXR), a major regulator of drug metabolism, in SHBG regulation. Serum SHBG was measured in four clinical trials (n = 61) and expression in in vitro experiments in human 3D hepatocyte spheroids and HepG2 cells.
Maria H. Ahonen +5 more
wiley +1 more source
Case Reports in Radiology, 2018 Localized hepatobiliary tuberculosis (TB) is a rare disorder which can present with an obstructive jaundice mimicking other noninfectious causes such as cholangiocarcinoma.
Rashid AL Umairi +2 more
doaj +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2627-2641, April 2026.Abstract Aims As type 2 diabetes (T2D) continues to rise globally and remains a major driver of cardiovascular disease, its remission has emerged as a therapeutic target. Current evidence supports bariatric surgery and low‐calorie diets with meal replacements.
Brighid McKay +19 more
wiley +1 more source
[Pseudotumoral hepatic tuberculosis].
Anales de medicina interna (Madrid, Spain : 1984), 1992 Liver infection as a result of tuberculosis is well known; there are several histological lesions, the most important being epithelioid cell granuloma. There are 3 anatomo-clinic variants: military or micronodular type, macronodular or pseudotumoral and pericanalicular of cholestatic.
A J, Corrales Torres +5 more
openaire +1 more source
Immunology, Volume 177, Issue 4, Page 810-823, April 2026.RNA‐seq of lungs and livers from Mycobacterium tuberculosis ‐infected mice with distinct disease outcomes revealed organ‐specific responses driven by differences in immune activity and bacterial burden. Meta‐analysis identified orthologous genes shared with human latent TB and mouse liver, with Creb3l1, Myo7b, Cyyr1 and Cbs differentially expressed and
Felipe T. Lima +9 more
wiley +1 more source
Quinic Acid and Synthetic Derivatives in Medicinal Chemistry
ChemMedChem, Volume 21, Issue 5, 13 March 2026.Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel +2 more
wiley +1 more source