Results 81 to 90 of about 70,657 (220)

Iron Regulation in Elderly Asian Elephants (Elephas maximus) Chronically Infected With Mycobacterium tuberculosis

Frontiers in Veterinary Science, 2020
Restriction of nutrients to pathogens (nutritional immunity) is a critical innate immune response mechanism that operates when pathogens such as Mycobacterium tuberculosis have the potential to evade humoral immunity.
Maja Ruetten, Hanspeter W. Steinmetz, Markus Thiersch, Marja Kik, Lloyd Vaughan, Sandro Altamura, Martina U. Muckenthaler, Martina U. Muckenthaler, Martina U. Muckenthaler, Max Gassmann, Max Gassmann   +10 more
doaj   +1 more source

Potential Biomarkers for Disease Stratification and Prognosis Prediction in Pediatric Asthma: LCN2, sST2 and FGF21

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers.
Xu Yang, Hai Wang, Yong‐Zheng Zhang, Yan‐Yan Chen, Xin‐Xin Xing, Yi‐Cheng Ding   +5 more
wiley   +1 more source

Nevirapine- and efavirenz-associated hepatotoxicity under programmatic conditions in Kenya and Mozambique. [PDF]

, 2012
To describe the frequency, risk factors, and clinical signs and symptoms associated with hepatotoxicity (HT) in patients on nevirapine- or efavirenz-based antiretroviral therapy (ART), we conducted a retrospective cohort analysis of patients attending ...
Biot, M, Chu, K M, Ford, N P, Manzi, M, Rasschaert, F, Zachariah, R, Zuniga, I   +6 more
core   +2 more sources

Computational Study on Potentially Active Antibacterial Compounds in Secondary Metabolites of Extremophilic Microorganisms

ChemistryOpen, EarlyView.
This study employed density functional theory (DFT) and conceptual DFT (CDFT) to calculate the structures and properties of potential antibacterial compounds derived from 16‐membered lactone ring‐containing secondary metabolites of extremophiles, as well as midecamycin.
Dilong Li, Yanni Wang, Yinhuan Huang, Hui Zhou, Xiaoyun Xia, Wei Huang, Chaojie Wang   +6 more
wiley   +1 more source

Acute brucella melitensis M16 infection model in mice treated with tumor necrosis factor-alpha inhibitors [PDF]

, 2015
Introduction: There is limited data in the literature about brucellosis related to an intracellular pathogen and anti-tumor necrosis factor alpha (anti-TNFα) medication.
Akalın, Ş., Demirkan, N., Ergin, Ç., Kutlu, Murat, Sayin-Kutlu, S., Zorbozan, O., Çobankara, V., Şahin, B., Şen-Türk, N.   +8 more
core   +1 more source

Primary hepatic tuberculosis: A rare occurrence [PDF]

Annals of Hepato-Biliary-Pancreatic Surgery, 2019
Primary hepatic tuberculosis is a rare entity and can closely mimic malignancy with respect to clinical presentation and imaging features. We identified five patients at a high volume tertiary care cancer center, whose clinical features and imaging closely mimicked primary liver malignancy or metastases but final histopathology was suggestive of ...
Niyogi, Devayani, Goel, Mahesh, Shinde, Rajesh S, Patkar, Shraddha   +3 more
openaire   +2 more sources

Characterisation of bacteria‐induced colitis and its modulation by probiotics in naked mole rats: a new mammalian model for acute inflammatory disease

The Journal of Pathology, EarlyView.
Abstract Enteropathogenic bacteria are a major cause of morbidity and mortality globally. While mouse models have been indispensable in advancing our understanding of infectious enteric diseases, key differences in intestinal microbiota and immunobiology between mice and humans underscore the need for alternative mammalian models that better ...
Daniel W. Hart, Aik Seng Ng, Patrycja Gazińska, Robert Goldin, Purva Gopal, Nicolize O'Dell, Ahmad Zargar, Lior Pytowski, Shamir Montazid, Chiara Bardella, James E. East, Ian P. Tomlinson, Nadine Koch, Nigel C. Bennett, Shazia Irshad   +14 more
wiley   +1 more source

Hepatic tuberculosis: a multimodality imaging review [PDF]

Insights into Imaging, 2015
Nuestro objetivo es ilustrar el espectro de imágenes multimodales de la implicación hepática en la tuberculosis (TB). Si bien la tuberculosis diseminada en las imágenes generalmente se manifiesta como múltiples lesiones nodulares pequeñas dispersas en el parénquima hepático, la tuberculosis hepática aislada sigue siendo una entidad rara e intrigante ...
Chandan Kakkar, Ashwin Polnaya, K Prakashini, S Smiti, KV Rajagopal, Ankur Arora   +5 more
openaire   +2 more sources

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Granulomatous liver diseases: A review

Journal of the Formosan Medical Association, 2012
Granulomas that consist of focal accumulations of macrophages are commonly found in the liver due to stimulation of the immune system by a number of agents.
Marcy Coash, Faripour Forouhar, Catherine H. Wu, George Y. Wu   +3 more
doaj   +1 more source