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Key impact of Beijing strains including new resistant clusters on spread of multidrug-resistant tuberculosis in northern Russia. [PDF]

Microbiol Spectr
Popova Y, Vyazovaya A, Eliseev P, Miteneva E, Polev D, Mokrousov I, Mariandyshev A.   +6 more
europepmc   +1 more source

Gender disparities in multidrug-resistant tuberculosis notifications in Uganda: evidence from national surveillance data, 2014-2023

Akello SR, Alunyo JP, Matovu JK, Mugasha E, Emetu J, Paasi G, Okibure A, Mukunya D, Olupot-Olupot P.   +8 more
europepmc   +1 more source

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Multidrug-resistant tuberculosis

Clinica Chimica Acta
One of predominant contributors to global mortality is tuberculosis (TB), an infection caused by Mycobacterium tuberculosis (MTB). Inappropriate and ineffectual treatment can lead to the development of drug-resistant TB. One of the most common forms of drug-resistant TB is multidrug-resistant tuberculosis (MDR-TB), caused by mutations in the rpoB and ...
Dika Apriliana, Wulandari, Yeni Wahyuni, Hartati, Abdullahi Umar, Ibrahim, Dian Ayu Eka, Pitaloka, , Irkham   +4 more
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Management of Multidrug-Resistant Tuberculosis

Seminars in Respiratory and Critical Care Medicine, 2013
AbstractDrug-resistant strains of Mycobacterium tuberculosis pose a major threat to global tuberculosis control. Despite the availability of curative antituberculosis therapy for nearly half a century, inappropriate and inadequate treatment of tuberculosis, as well as unchecked transmission of M.
Charles L, Daley, Jose A, Caminero
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Multidrug resistance in Mycobacterium tuberculosis

International Journal of Antimicrobial Agents, 1997
All but one of the four major mechanisms of resistance to antimicrobial agents-inactivation of the drug, altered cell wall permeability or drug efflux, drug titration due to target overproduction, and alteration of the target by mutation-appear to be employed by Mycobacterium tuberculosis in its resistance to components of short course chemotherapy ...
B, Heym, S T, Cole
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Treatment of Multidrug-Resistant Tuberculosis

New England Journal of Medicine, 1993
The frequency of infections with M. tuberculosis resistant to antituberculous drugs is increasing in the United States and globally. This increase is a major threat to tuberculosis treatment and control programs. To prevent this situation from worsening, initial treatment programs that entail directly observed therapy supported by effective inducements
Alastair J.J. Wood, Michael D. Iseman
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Multidrug resistant cervical tuberculosis

American Journal of Otolaryngology, 1999
Tuberculosis (TB) remains a global health problem, with an annual incidence of 8 to 10 million cases and the death of 3 million people year1y.l Despite the continuous decline of TB in the United States since the 185Os, an increase in new TB cases was observed in 1985.
A J, Vartanian, A, Alvi
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Confronting Multidrug-Resistant Tuberculosis

New England Journal of Medicine, 2012
Microbial resistance to antituberculosis drugs has existed since the dawn of the antibiotic era.1 Multidrug-resistant (MDR) tuberculosis, defined by resistance to isoniazid and rifampin, requires treatment for up to 2 years with expensive second-line drugs that have poor side-effect profiles; success rates rarely exceed 65 to 75%.
Richard E, Chaisson, Eric L, Nuermberger
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Multidrug-resistant tuberculosis

Infectious Disease Clinics of North America, 2002
Multidrug-resistant TB is a growing public health problem. Although control of the multidrug-resistant TB epidemic has been achieved in New York City, strains of multidrug-resistant TB are found in nearly every state. Much of the world faces a growing problem with no immediate solution.
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