Results 81 to 90 of about 1,138,448 (263)

Clinical efficacy and safety of ultra-short-course chemotherapy in treatment of spinal tuberculosis after complete debridement: an observational study

open access: yesJournal of International Medical Research, 2021
Objective To evaluate the clinical efficacy and safety of ultra-short-course chemotherapy (
Guangwei Sun   +9 more
semanticscholar   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

open access: yesAdvanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi   +4 more
wiley   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott   +7 more
wiley   +1 more source

Minimally invasive spinal surgery in spinal tuberculosis – A case report series

open access: yesInterdisciplinary Neurosurgery, 2021
Spinal tuberculosis is increasing in prevalence in sub Saharan Africa as we find ourselves at the epicentre of immunosuppression secondary to a human immunodeficiency pandemic.
Adrian Kelly   +2 more
doaj   +1 more source

Isolated tuberculosis of the posterior spinal elements: case report and discussion of management [PDF]

open access: yes, 2014
In neurologically intact patients with isolated tuberculosis of the posterior spinal elements, surgical intervention can be of benefit in select patients by reducing instability, deformity and late ...
Al-Khudairi, N., Meir, A.
core   +1 more source

Clinical Pharmacology Quality Assurance Program for Global HIV and Co‐Infection Drug Development

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
When the acquired immunodeficiency syndrome emerged in the 1980s, the United States National Institutes of Health established research networks to conduct clinical trials with the pharmaceutical industry to identify effective antiretroviral therapeutics.
Robin DiFrancesco   +17 more
wiley   +1 more source

Evolution of surgery for active spinal tuberculosis in adults: A narrative review

open access: yesJournal of Orthopaedic Reports
Background: Surgical management of Tuberculosis (Tb) spine has evolved from debridement and laminectomy to navigation assisted procedures; from high morbidity and mortality to excellent clinical outcomes. Objective: The objective of this narrative review
Borde Mandar   +2 more
doaj   +1 more source

Atypical imaging of spinal tuberculosis: a case report and review of literature

open access: yesThe Pan African Medical Journal, 2016
This is a case report of spinal tuberculosis combined with sacroiliac joint tuberculosis, pulmonary tuberculosis, chest wall tuberculosis and tuberculous pleurisy and the image of the patient is rare, special and not typical and it looks like a halo sign.
Huijun Zhang, Zenghui Lu
doaj   +1 more source

Surgical Treatment for Spinal Tuberculosis without Elevation of Inflammatory Biomarkers at the Initial Visit Mimicking Spinal Metastasis

open access: yesCase Reports in Orthopedics, 2020
Here, we report a case of spinal tuberculosis without elevation of C-reactive protein (CRP) at the initial visit mimicking spinal metastasis. A 70-year-old woman developed progressive paraplegia without a history of injury and came to our hospital for ...
Takuya Sakamoto   +22 more
doaj   +1 more source

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