Results 51 to 60 of about 1,198,187 (379)

Estimation of underreporting in Brazilian tuberculosis data, 2012-2014 [PDF]

arXiv, 2021
Analysis of burden of underregistration in tuberculosis data in Brazil, from 2012 to 2014. Approches of Oliveira et al. (2020) and Stoner et al. (2019) are applied. The main focus is to illustrated how the approach of Oliveira et al. (2020) can be applied when the clustering structure is not previously available.
arxiv  

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

FEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva, Marcio Vinicius Bertacine Dias   +1 more
wiley   +1 more source

Infection control and tuberculosis among health care workers in Viet Nam, 2009-2013: a cross-sectional survey

BMC Infectious Diseases, 2016
Background Data on tuberculosis (TB) among health care workers (HCW) and TB infection control (TBIC) indicators are rarely available at national level. We assessed multi-year trends in notification data of TB among HCW and explored possible associations ...
Edine W. Tiemersma, Nguyen Thien Huong, Pham Hoang Yen, Bui Thi Tinh, Tran Thi Bich Thuy, Nguyen Van Hung, Nguyen Thanh Mai, Suzanne Verver, Agnes Gebhard, Nguyen Viet Nhung   +9 more
doaj   +1 more source

Empowering Tuberculosis Screening with Explainable Self-Supervised Deep Neural Networks [PDF]

2024 International Conference on Machine Learning and Applications (ICMLA), Miami, FL, USA, 2024, pp. 794-797
Tuberculosis persists as a global health crisis, especially in resource-limited populations and remote regions, with more than 10 million individuals newly infected annually. It stands as a stark symbol of inequity in public health. Tuberculosis impacts roughly a quarter of the global populace, with the majority of cases concentrated in eight countries,
arxiv   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

X-RAY MORPHOLOGICAL SEMIOTICS OF NON-TUBERCULOUS MYCOBACTERIAL PULMONARY DISEASE

Вестник рентгенологии и радиологии, 2018
Objective: to evaluate the X-ray radiological features of nontuberculous mycobacterial pulmonary disease (NTMPD) versus morphological findings.Material and methods.
R. B. Amansakhedov, L. N. Lepekha, L. I. Dmitrieva, I. Yu. Andrievskaya, A. T. Sigaev, N. N. Makar’yants, V. V. Romanov, A. E. Ergeshov   +7 more
doaj   +1 more source

Design of an Efficient, Ease-of-use and Affordable Artificial Intelligence based Nucleic Acid Amplification Diagnosis Technology for Tuberculosis and Multi-drug Resistant Tuberculosis [PDF]

arXiv, 2021
Current technologies that facilitate diagnosis for simultaneous detection of Mycobacterium tuberculosis and its resistance to first-line anti-tuberculosis drugs (Isoniazid and Rifampicim) are designed for lab-based settings and are unaffordable for large scale testing implementations.
arxiv  

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Strukturaufklärung, Totalsynthese, In‐Vivo‐Aktivität und Potentieller Biosyntheseweg des Neuen Myxobakteriellen Antibiotikums Corramycin**

Angewandte Chemie, Volume 134, Issue 51, December 19, 2022., 2022
Corramycin ist ein neuer Naturstoff, welcher von dem Myxobakterium Corallococcus coralloides produziert wird. Seine Struktur sowie die außergewöhnliche Total‐ und Biosynthese des Antibiotikums werden hier zum ersten Mal beschrieben. Corramycin zeigt keine Zytotoxizität und keine Kreuzresistenz mit gängigen Antibiotikaklassen.
Cédric Couturier, Sebastian Groß, Alexander von Tesmar, Judith Hoffmann, Selina Deckarm, Anouchka Fievet, Nelly Dubarry, Thomas Taillier, Christoph Pöverlein, Heike Stump, Michael Kurz, Luigi Toti, Sabine Haag Richter, Dietmar Schummer, Philippe Sizun, Michael Hoffmann, Ram Prasad Awal, Nestor Zaburannyi, Kirsten Harmrolfs, Joachim Wink, Emilie Lessoud, Thierry Vermat, Veronique Cazals, Sandra Silve, Armin Bauer, Michael Mourez, Laurent Fraisse, Corinne Leroi‐Geissler, Astrid Rey, Stéphanie Versluys, Eric Bacqué, Rolf Müller, Stephane Renard   +32 more
wiley   +1 more source

Addressing the burden and detection gap of latent tuberculosis infection in schoolchildren and adolescents in China: a cross-sectional study

BMC Infectious Diseases
Background The latent tuberculosis infection (LTBI) burden is still unclear in schoolchildren and adolescents in China. Previous study and daily surveillance data indicate a LTBI detection gap.
Bo Wu, Ya Yu, Chengguo Wu, Yaling Shi, Ying Liu, Jin Yin, Qian Su, Zhengyu Zhang, Xueyong Huang, Mei Wang, Yan Pang, Jiyuan Zhong, Jun Fan   +12 more
doaj   +1 more source