Genomic Profiling of Mycobacterium tuberculosis Strains, Myanmar
Multidrug resistance is a major threat to global elimination of tuberculosis (TB). We performed phenotypic drug-susceptibility testing and whole-genome sequencing for 309 isolates from 342 consecutive patients who were given a diagnosis of TB in Yangon ...
Htin Lin Aung +9 more
doaj +1 more source
Epidemiology of Nontuberculous Mycobacterial Infection, South Korea, 2007–2016
The prevalence and incidence of nontuberculous mycobacterial (NTM) infections increased in South Korea from 2007 to 2016. Annual prevalence of NTM infection increased to 39.6 cases/100,000 population in 2016 and annual incidence to 19.0 cases/100,000 ...
Hyewon Lee +4 more
doaj +1 more source
A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. [PDF]
The Mycobacterium tuberculosis TetR-type regulator Rv3574 has been implicated in pathogenesis as it is induced in vivo, and genome-wide essentiality studies show it is required for infection.
Withers, Mike +41 more
core +1 more source
Interferon-gamma and skin test responses of schoolchildren in southeast England to purified protein derivatives from Mycobacterium tuberculosis and other species of mycobacteria. [PDF]
The immune responses of schoolchildren in southeast England to Mycobacterium tuberculosis and other species of mycobacteria were studied prior to vaccination with bacille Calmette-Guérin (BCG).
Branson, K +9 more
core +1 more source
Pyrolysis Mass Spectrometry: A New Method to Differentiate Between the Mycobacteria of the "Tuberculosis Complex" and Other Mycobacteria [PDF]
Pyrolysis mass spectrometry (p.m.s.) was applied to differentiate 91 coded mycobacteria as belonging to either the 'tuberculosis complex' (M. tuberculosis, M. bovis and M. bovis BCG) or to other species of Mycobacterium. Strains were analysed in batches; in each batch three strains each of M. tuberculosis, M. bovis and M.
G, Wieten +4 more
openaire +2 more sources
Sensitive detection of gene expression in mycobacteria under replicating and non-replicating conditions using optimized far-red reporters. [PDF]
Fluorescent reporter proteins have proven useful for imaging techniques in many organisms. We constructed optimized expression systems for several fluorescent proteins from the far-red region of the spectrum and analyzed their utility in several ...
Schreuder Lise J. +39 more
core +1 more source
The US Centers for Disease Control and Prevention recommends screening populations at increased risk for tuberculosis (TB), including persons born in countries with high TB rates.
Clarisse A. Tsang +3 more
doaj +1 more source
Molecular analysis of Mycobacterium tuberculosis DNA from a family of 18th century Hungarians [PDF]
The naturally mummified remains of a mother and two daughters found in an 18th century Hungarian crypt were analysed, using multiple molecular genetic techniques to examine the epidemiology and evolution of tuberculosis.
Spigelman, Mark +16 more
core +1 more source
Tuberculosis Outbreak in a Primary School, Milan, Italy
Investigation of an outbreak of tuberculosis (TB) in a primary school in Milan, Italy, found 15 schoolchildren had active TB disease and 173 had latent TB infection. TB was also identified in 2 homeless men near the school. Diagnostic delay, particularly
Marino Faccini +12 more
doaj +1 more source
Management of infection with nontuberculosis mycobacteria [PDF]
The nontuberculosis mycobacteria are often naturally resistant to the conventional antibiotics and to antituberculosis drugs (1–3). In addition, providing advice for the treatment of nontuberculosis is complicated by the variable and changing ...
Gillespie, Stephen H. +1 more
core +1 more source

