Results 21 to 30 of about 9,752 (166)

Modulation of succinyl‐CoA:3‐ketoacid CoA transferase activity by a single amino acid residue in acetate:succinate CoA transferase from Trypanosoma brucei, the causative agent of African sleeping sickness

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Trypanosomatids are protozoan parasites that remain a global health challenge due to the limited efficacy, safety, and durability of current treatments. Acetate: succinate CoA transferase (ASCT), together with succinyl‐CoA synthase (SCS), forms the ASCT/SCS cycle that fuels ATP production and generates acetate, a central metabolic intermediate
Kota Mochizuki, Daniel Ken Inaoka, Keisuke Fukuda, Hana Kurasawa, Kenji Iyoda, Uta Nakai, Shigeharu Harada, Emmanuel O. Balogun, Frédéric Bringaud, Michael Boshart, Takaya Sakura, Kenji Hirayama, Kiyoshi Kita, Tomoo Shiba   +13 more
wiley   +1 more source

The Argentine experience with human immune deficiency virus positive patients in the waiting list for liver transplantation: preliminary analysis [PDF]

, 2013
Previamente, la seropositividad para el virus de la inmunodeficiencia humana (HIV) era una contraindicación absoluta del trasplante. Sin embargo, reportes de la época posterior al tratamiento antirretroviral altamente activo (HAART) demostraron que los ...
Bandi, Juan Carlos, Barcán, Laura, Bisignano, Liliana, de Santibañes, Eduardo, Gadano, Adrián, Gondolesi, Gabriel Eduardo, McCormack, Lucas, Orozco, Federico, Villamil, Alejandra   +8 more
core  

Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory

Immunology, Volume 177, Issue 2, Page 254-269, February 2026.
We utilised a commercially available adjuvant formulation to study the induction, maintenance, and consequences of innate immune memory. Using functional assays on bone marrow‐derived innate cells, extensive transcriptomic analysis of haematopoietic progenitors, and challenge models of spirochetal infection, nonspecific inflammation, and model antigen ...
Samuel T. Pasco, Itziar Martín‐Ruiz, Sarai Araujo‐Aris, Diego Barriales, Janire Castelo, Leire Egia‐Mendikute, Monika Gonzalez, Jose Ezequiel Martin, Elena Molina, Maitane Mugica, Ainhoa Palacios, Iratxe Seoane, Naiara Gutiez, Estibaliz Atondo, Eneko Santos Fernández, Maddi Oyanguren, Borja Jimenez‐Lasheras, Ainize Peña‐Cearra, Ana M. Aransay, Asis Palazon, Aize Pellón, Leticia Abecia, Hector Rodriguez, Natalia Elguezabal, Juan Anguita   +24 more
wiley   +1 more source

Modulatory activity of antioxidants against the toxicity of Rifampicin in vivo Atividade modulatória de anti-oxidantes contra a toxicidade da rifampicina in vivo

Revista do Instituto de Medicina Tropical de São Paulo, 2010
The World Health Organization (WHO) has shown concern about the burden of tuberculosis in the developing countries. Even though rifampicin is an effective drug in the management of tuberculosis, it has been documented to have some toxic effects in humans.
Olufunsho Awodele, Alade Akintonwa, Vincent O. Osunkalu, Herbert A.B. Coker   +3 more
doaj   +1 more source

Resultados del tratamiento de la hepatitis C con antivirales de acción directa [PDF]

, 2016
La Hepatitis C (VHC) es la causa más frecuente de cirrosis hepática en el mundo occidental. En el último año, la aparición de nuevos antivirales de acción directa (AAD) ha mejorado la tasa de respuesta viral sostenida (RVS) y la seguridad del tratamiento.
Romero Moreno, Sarai
core  

International Survey of Gastroenterologists on Managing Inflammatory Bowel Disease During Pregnancy and Lactation: Current State and the Necessity for Improvements

United European Gastroenterology Journal, Volume 13, Issue 10, Page 1999-2011, December 2025.
ABSTRACT Background Reproduction is a fundamental aspect of life. This study aimed to provide an international overview of gastroenterologists' approaches to managing inflammatory bowel disease (IBD) during preconception, pregnancy, lactation, and postpartum. Methods An anonymous 75‐question survey was distributed to gastroenterologists in 36 countries,
María José Casanova, Javier P. Gisbert, Aurelien Amiot, Hannah Gordon, Gionata Fiorino, Emma Flanagan, Paulo Gustavo Kotze, Aleksandra Sokic‐Milutinovic, Elena Sonnenberg, Paulina Nuñez, Andreas Blesl, Ignacio Catalán‐Serra, Peter Bossuyt, Rafal Filip, Ariella Bar‐Gil Shitrit, Anna Kagramanova, Zeljko Krznaric, Paulina Molander, Gerassimos J. Mantzaris, Pascal Juillerat, Tamas Molnar, Krisztina B. Gecse, Joana Torres, Pär Myrelid, Uma Mahadevan, Juan Ricardo Márquez, Beatriz Maria Iade‐Vergara, Astrid Rausch, Dana Duricova, Mette Julsgaard, María Chaparro   +30 more
wiley   +1 more source

Ring enhancing intracranial lesion responding to antituberculous treatment in an HIV-infected patient Lesão intracraniana que respondeu ao tratamento anti-tuberculoso em paciente infectado pelo HIV

Revista do Instituto de Medicina Tropical de São Paulo, 2010
Cerebral tuberculomas constitute a major differential diagnosis of cerebral toxoplasmosis in human immunodeficiency virus (HIV)-infected patients in developing countries.
Daniela Pellegrino, Juliana Gerhardt, Fátima M.V. Porfírio, Edgar de Bortholi Santos, Rafi F. Dauar, Augusto C. Penalva de Oliveira, José E. Vidal   +6 more
doaj   +1 more source

Peliosis hepática: presentación de un caso con correlación radiológica y patológica

Anales de Radiología, México
La peliosis hepática es un trastorno benigno poco común caracterizado por la presencia de dilatación y ocupación por sangre de los sinusoides hepáticos.
Carmen K. Márquez-Lozano, David R. García-Huereca, David F. Cuevas-Cueto, David Aguilar-Obeso, Víctor R. de Alba-Ramírez   +4 more
doaj   +1 more source

Association of Fasciola gigantica Co-infection With Bovine Tuberculosis Infection and Diagnosis in a Naturally Infected Cattle Population in Africa

Frontiers in Veterinary Science, 2018
Bovine tuberculosis (bTB), caused by Mycobacterium bovis, remains a major livestock and public health problem in both high and low-income countries. With the current absence of an effective vaccine, control in cattle populations is reliant on regular ...
Robert F. Kelly, Robert F. Kelly, Rebecca Callaby, Nkongho F. Egbe, Diana J. L. Williams, Ngu Ngwa Victor, Vincent N. Tanya, Melissa Sander, Lucy Ndip, Richard Ngandolo, Kenton L. Morgan, Ian G. Handel, Ian G. Handel, Stella Mazeri, Adrian Muwonge, Barend M. de C Bronsvoort   +15 more
doaj   +1 more source

Nota sobre la revista "Ars Medica" [PDF]

, 2012
Sinopsi breu sobre el contingut de la revista «Ars Medica», editada a Barcelona entre els anys 1925 i 1936. Notícia dels seus fundadors, principalment els doctors Bartrina, Battestini, Carulla, Mas Oliver, Otero, Salarich, Trias de Bes i Vanrell. El 1932
Calbet i Camarasa, Josep M. (Josep Maria)
core