Tuberculosis vaccines: Rising opportunities. [PDF]
PLoS Medicine, 2019 Johan Vekemans, Katherine O'Brien, and Jeremy Farrar discuss recent breakthroughs in the search for a highly effective tuberculosis vaccine.
Johan Vekemans +2 more
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Tuberculosis vaccines in the era of Covid-19 – what is taking us so long? [PDF]
EBioMedicine, 2022 Summary: The Mycobacterium bovis BCG vaccine was first used in 1921, but has not controlled the global spread of tuberculosis (TB). There are still no new licensed tuberculosis vaccines, although there much active research and a vaccine development ...
Hazel M. Dockrell, Helen McShane
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Tuberculosis Vaccines and T Cell Immune Memory [PDF]
VaccinesTuberculosis (TB) remains a major infectious disease partly due to the lack of an effective vaccine. Therefore, developing new and more effective TB vaccines is crucial for controlling TB. Mycobacterium tuberculosis (M.
Fei Li +6 more
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Mucosal delivery of tuberculosis vaccines: a review of current approaches and challenges. [PDF]
Expert Rev Vaccines, 2019 Introduction: Tuberculosis (TB) remains a major health threat and it is now clear that the current vaccine, BCG, is unable to arrest the global TB epidemic. A new vaccine is needed to either replace or boost BCG so that a better level of protection could
Stylianou E +3 more
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Vaccination Against Tuberculosis: Revamping BCG by Molecular Genetics Guided by Immunology
Frontiers in Immunology, 2020 Tuberculosis (TB) remains a major health threat. Although a vaccine has been available for almost 100 years termed Bacille Calmette-Guérin (BCG), it is insufficient and better vaccines are urgently needed.
Stefan H. E. Kaufmann +1 more
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The current status, challenges, and future developments of new tuberculosis vaccines [PDF]
Human Vaccines & Immunotherapeutics, 2018 Mycobacterium tuberculosis complex causes tuberculosis (TB), one of the top 10 causes of death worldwide. TB results in more fatalities than multi-drug resistant (MDR) HIV strain related coinfection. Vaccines play a key role in the prevention and control
Wenping Gong, Yan Liang, Xueqiong Wu
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Insight Into Novel Anti-tuberculosis Vaccines by Using Immunoinformatics Approaches. [PDF]
Front Microbiol, 2022 Khan Z +5 more
europepmc +3 more sources
Natural variation in immune responses to neonatal mycobacterium bovis bacillus calmette-guerin (BCG) vaccination in a cohort of Gambian infants [PDF]
, 2008 Background There is a need for new vaccines for tuberculosis (TB) that protect against adult pulmonary disease in regions where BCG is not effective.
A Lalvani +46 more
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Advance in strategies to build efficient vaccines against tuberculosis
Frontiers in Veterinary Science, 2022 Tuberculosis is a chronic consumptive infectious disease, which can cause great damage to human and animal health all over the world. The emergence of multi-drug resistant strains, the unstable protective effect of Bacillus Calmette-Guérin (BCG) vaccine ...
Wei Qu +9 more
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