Results 11 to 20 of about 107,231 (299)

Tuberculosis vaccines [PDF]

open access: yesBritish Medical Bulletin, 2002
The increasing incidence of disease associated with HIV infection highlights the crucial role of the immune response in susceptibility to tuberculosis and has stimulated renewed efforts to develop improved vaccines. Vaccine targets include prevention of infection in naive individuals, prevention of re-activation in individuals harbouring latent ...
Young, DB, Stewart, GR
openaire   +3 more sources

Listeria-Vectored Multiantigenic Tuberculosis Vaccine Enhances Protective Immunity against Aerosol Challenge with Virulent Mycobacterium tuberculosis in BCG-Immunized C57BL/6 and BALB/c Mice

open access: yesmBio, 2022
Mycobacterium tuberculosis infects approximately one-third of the world's population, causing active tuberculosis (TB) in ~10 million people and death in ~1.5 million people annually. A potent vaccine is needed to boost the level of immunity conferred by
Qingmei Jia   +3 more
doaj   +1 more source

Adjuvants and Antigen-Delivery Systems for Subunit Vaccines against Tuberculosis

open access: yesVaccines, 2021
The only licensed vaccine against tuberculosis is BCG. However, BCG has failed to provide consistent protection against tuberculosis, especially pulmonary disease in adults.
Abu Salim Mustafa
doaj   +1 more source

Is neglect of self-clearance biasing TB vaccine impact estimates?

open access: yesBMJ Global Health, 2023
Background Mathematical modelling has been used extensively to estimate the potential impact of new tuberculosis vaccines, with the majority of existing models assuming that individuals with Mycobacterium tuberculosis (Mtb) infection remain at lifelong ...
Richard White   +6 more
doaj   +1 more source

Bacterial outer membrane vesicles and vaccine applications [PDF]

open access: yes, 2014
Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Acevedo, Reinaldo   +10 more
core   +6 more sources

The Diversity Outbred Mouse Population Is an Improved Animal Model of Vaccination against Tuberculosis That Reflects Heterogeneity of Protection

open access: yesmSphere, 2020
Many studies of Mycobacterium tuberculosis infection and immunity have used mouse models. However, outcomes of vaccination and challenge with M. tuberculosis in inbred mouse strains do not reflect the full range of outcomes seen in people.
Sherry L. Kurtz   +5 more
doaj   +1 more source

Analysis of prevalence of HIV-1 primary resistance to antiretroviral drugs in the territory of Moscow and Moscow region

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. To analyze the level of HIV drug resistance among primary patients (who did not receive antiretroviral therapy (ART)) living in the Moscow region, where access to the antiretroviral therapy is quite high.Material and methods.
M. N. Nosik   +6 more
doaj   +1 more source

Update on TB Vaccine Pipeline

open access: yesApplied Sciences, 2020
In addition to antibiotics, vaccination is considered among the most efficacious methods in the control and the potential eradication of infectious diseases. New safe and effective vaccines against tuberculosis (TB) could be a very important tool and are
Carlos Martin   +3 more
doaj   +1 more source

Vaccine prophylaxis of intercurrent infections of respiratory tract in patients with tuberculosis

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2019
In this review, on the base of analysis of the current epidemiological data, the objective preconditions of the growing role of vaccinal prevention in increasing of effectiveness of treatment of tuberculosis in the key groups of patient is elucidated ...
K. V. Mashilov, T. A. Kostinova
doaj   +1 more source

Association of Tuberculosis and Infections of Herpes Simplex, Varicella Zoster Viruses and Cytomegalovirus

open access: yesЭпидемиология и вакцинопрофилактика, 2015
To determine frequency of Herpes simplex (HSV), Varicella zoster viral (VZV) and Сytomegaloviral (CMV) coinfection with tuberculosis (TB) we examined 45 patients with pulmonary TB and 62 healthy donors, 25 of them were healthcare workers in tuberculosis ...
A. S. Kazanova   +3 more
doaj   +1 more source

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