Results 11 to 20 of about 107,231 (299)
The increasing incidence of disease associated with HIV infection highlights the crucial role of the immune response in susceptibility to tuberculosis and has stimulated renewed efforts to develop improved vaccines. Vaccine targets include prevention of infection in naive individuals, prevention of re-activation in individuals harbouring latent ...
Young, DB, Stewart, GR
openaire +3 more sources
Mycobacterium tuberculosis infects approximately one-third of the world's population, causing active tuberculosis (TB) in ~10 million people and death in ~1.5 million people annually. A potent vaccine is needed to boost the level of immunity conferred by
Qingmei Jia +3 more
doaj +1 more source
Adjuvants and Antigen-Delivery Systems for Subunit Vaccines against Tuberculosis
The only licensed vaccine against tuberculosis is BCG. However, BCG has failed to provide consistent protection against tuberculosis, especially pulmonary disease in adults.
Abu Salim Mustafa
doaj +1 more source
Is neglect of self-clearance biasing TB vaccine impact estimates?
Background Mathematical modelling has been used extensively to estimate the potential impact of new tuberculosis vaccines, with the majority of existing models assuming that individuals with Mycobacterium tuberculosis (Mtb) infection remain at lifelong ...
Richard White +6 more
doaj +1 more source
Bacterial outer membrane vesicles and vaccine applications [PDF]
Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Acevedo, Reinaldo +10 more
core +6 more sources
Many studies of Mycobacterium tuberculosis infection and immunity have used mouse models. However, outcomes of vaccination and challenge with M. tuberculosis in inbred mouse strains do not reflect the full range of outcomes seen in people.
Sherry L. Kurtz +5 more
doaj +1 more source
Aim. To analyze the level of HIV drug resistance among primary patients (who did not receive antiretroviral therapy (ART)) living in the Moscow region, where access to the antiretroviral therapy is quite high.Material and methods.
M. N. Nosik +6 more
doaj +1 more source
In addition to antibiotics, vaccination is considered among the most efficacious methods in the control and the potential eradication of infectious diseases. New safe and effective vaccines against tuberculosis (TB) could be a very important tool and are
Carlos Martin +3 more
doaj +1 more source
Vaccine prophylaxis of intercurrent infections of respiratory tract in patients with tuberculosis
In this review, on the base of analysis of the current epidemiological data, the objective preconditions of the growing role of vaccinal prevention in increasing of effectiveness of treatment of tuberculosis in the key groups of patient is elucidated ...
K. V. Mashilov, T. A. Kostinova
doaj +1 more source
To determine frequency of Herpes simplex (HSV), Varicella zoster viral (VZV) and Сytomegaloviral (CMV) coinfection with tuberculosis (TB) we examined 45 patients with pulmonary TB and 62 healthy donors, 25 of them were healthcare workers in tuberculosis ...
A. S. Kazanova +3 more
doaj +1 more source

