Results 91 to 100 of about 178,050 (257)

Noninvasive 11C-rifampin positron emission tomography reveals drug biodistribution in tuberculous meningitis

Science Translational Medicine, 2018
PET reveals spatially heterogeneous rifampin brain penetration, which decreases rapidly with treatment during tuberculous meningitis. TB on the brain Children and immunodeficient individuals are especially prone to tuberculosis infections in the brain ...
E. Tucker, B. Guglieri-Lopez, A. Ordonez, Brittaney E. Ritchie, Mariah H. Klunk, Richa Sharma, Yong S. Chang, J. Sanchez-Bautista, Sarah M. Frey, M. Lodge, S. Rowe, D. Holt, J. Gobburu, C. Peloquin, W. B. Mathews, R. Dannals, C. Pardo, S. Kannan, V. Ivaturi, Sanjay K. Jain   +19 more
semanticscholar   +1 more source

Crohn's Disease With Latent Tuberculosis Infection or Intestinal Tuberculosis: Rapid Discrimination by Targeted Next‐Generation Sequencing

Alimentary Pharmacology &Therapeutics, Volume 61, Issue 7, Page 1218-1225, April 2025.
For patients with difficultlty in differentiation diagnosis, targeted next‐generation sequencing can facilitate the rapid diagnosis of intestinal tuberculosis and effectively discriminate it from Crohn's disease with latent tuberculosis infection in clinical practice.
Lingna Ye, Yushu Cao, Yujuan Fu, Chuwen Tian, Qian Cao   +4 more
wiley   +1 more source

Proresolving mediator profiles in cerebrospinal fluid are linked with disease severity and outcome in adults with tuberculous meningitis

The FASEB Journal, 2019
Tuberculous meningitis (TBM) is the most lethal form of tuberculosis infection, characterized by a dysregulated immune response that frequently leads to neurologic injury and death despite the best available treatment.
R. Colas, L. Nhat, N. Thuong, Esteban A. Gomez, Lucy Ly, Hai Hoang Thanh, N. H. Mai, N. Phu, G. Thwaites, Jesmond Dalli   +9 more
semanticscholar   +1 more source

Delamanid Central Nervous System Pharmacokinetics in Tuberculous Meningitis in Rabbits and Humans

Antimicrobial Agents and Chemotherapy, 2019
Central nervous system tuberculosis (TB) is devastating and affects vulnerable populations. Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculous meningitis (TBM) specifically are nearly uniformly fatal, with little information being
E. Tucker, L. Pieterse, M. Zimmerman, Z. Udwadia, C. Peloquin, M. T. Gler, S. Ganatra, J. Tornheim, Prerna K. Chawla, Janice C. Caoili, Brittaney E. Ritchie, Sanjay K. Jain, V. Dartois, K. Dooley   +13 more
semanticscholar   +1 more source

The Definitive Diagnosis of Tuberculous Meningitis (TBM) di RSUP dr. Kariadi Semarang Descriptive study in adult patients using IS6110-based PCR amplification for detecting Mycobacterium tuberculosis

Sains Medika, 2013
Tuberculous meningitis (TBM) is the most common cause of central nervous system infection and has very high morbidity and mortality. The definitive diagnosis of TBM in RSUP dr Kariadi Semarang has been insufficient.
Masfiyah Masfiyah, Aris Catur Bintoro, Purnomo Hadi   +2 more
doaj   +1 more source

Corticosteroids for managing tuberculous meningitis

Cochrane Database of Systematic Reviews, 2016
Background Tuberculous meningitis is a serious form of tuberculosis (TB) that affects the meninges that cover a person's brain and spinal cord. It is associated with high death rates and with disability in people who survive.
K. Prasad, Mamta B. Singh, H. Ryan
semanticscholar   +1 more source

Demographic profiles and risk factors for mortality in acute meningitis: A nationwide population‐based observational study

Acute Medicine & Surgery
Aim Acute meningitis encompasses bacterial, viral (aseptic), fungal, tuberculous, and carcinomatous meningitis. The rate and risks of mortality in each type remain uncertain. This study aimed to elucidate these aspects in each type of meningitis. Methods
Tetsuya Akaishi, Kunio Tarasawa, Kiyohide Fushimi, Nobuo Yaegashi, Masashi Aoki, Kenji Fujimori   +5 more
doaj   +1 more source

Features tuberculous etiology meningitis in young children

Бюллетень сибирской медицины, 2012
The appointment of anti-TB drugs with meningitis tuberculous etiology later than the 10th day of illness in most cases leads to an unfavorable outcome of the disease and the development of serious complications. Specific therapy, conducted by the anti-TB
O. V. Kolokolova, L. V. Kuzmina, O. V. Filinyuk, O. O. Kaminsky, O. A. Novoselova   +4 more
doaj   +1 more source

Prospective Cohort Study on Performance of Cerebrospinal Fluid (CSF) Xpert MTB/RIF, CSF Lipoarabinomannan (LAM) Lateral Flow Assay (LFA), and Urine LAM LFA for Diagnosis of Tuberculous Meningitis in Zambia

Journal of Clinical Microbiology, 2019
Tuberculous meningitis (TBM) is a devastating infection of the central nervous system lacking an adequate point-of-care diagnostic test. We conducted a prospective cohort study of 550 Zambian adults with suspected TBM to determine the diagnostic accuracy
O. Siddiqi, G. Birbeck, M. Ghebremichael, Eugene Mubanga, Shawn Love, Clayton Buback, B. Kosloff, H. Ayles, M. Atadzhanov, K. Dheda, I. Koralnik   +10 more
semanticscholar   +1 more source

Aspirin in tuberculous meningitis [PDF]

EClinicalMedicine, 2021
Angharad G Davis, Robert J Wilkinson
openaire   +6 more sources