Results 11 to 20 of about 19,388 (180)

Efficacy and Safety of Corticosteroids in Tuberculous Meningitis: Systematic Review, Meta-Analysis, and Meta-Regression. [PDF]

Brain Behav
ABSTRACT Background Tuberculous meningitis (TBM) carries a case fatality rate of up to 50% in resource‐limited settings despite standard anti‐tuberculosis therapy. Adjunctive corticosteroids are widely recommended, yet their effect on mortality and safety across diverse populations remains imprecisely defined.
Younas A, Noor R, Shaukat MT, Ijlal A, Tariq I, Satea M, Almas MS, Jamil R, Sherwani MRK, Valverde NNG, Qadri M, Siddiqi M, Qureshi K, Yangi K, Chaurasia B.   +14 more
europepmc   +2 more sources

Contezolid in the Treatment of Multidrug-Resistant Tuberculous Meningitis: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Multidrug‐resistant tuberculous meningitis (MDR‐TBM) has a high mortality rate, and treatment options are limited. Linezolid is recommended for refractory cases but often causes intolerable adverse reactions such as peripheral neuropathy. Contezolid, a novel oxazolidinone, has shown better safety profiles in preclinical and early clinical ...
Wang N, Li X, Yan Q, Su H, Liu Y, Li Y, Yang C, Gu Y, Yan T, Wang Q, Liu X.   +10 more
europepmc   +2 more sources

Tuberculous meningitis

Nature Reviews Neurology, 2017
Tuberculosis remains a global health problem, with an estimated 10.4 million cases and 1.8 million deaths resulting from the disease in 2015. The most lethal and disabling form of tuberculosis is tuberculous meningitis (TBM), for which more than 100,000 new cases are estimated to occur per year.
Wilkinson, R.J., Rohlwink, U., Misra, U.K., Crevel, R. van, Mai, N.T.H., Dooley, K.E., Caws, M., Figaji, A., Savic, R., Solomons, R., Thwaites, G.E.   +10 more
openaire   +3 more sources

Undernutrition as Risk Factor of Hydrocephalus Prevalence in Children with Tuberculous Meningitis

Althea Medical Journal, 2017
Background: Hydrocephalus is the most frequent neurological complication in children with tuberculous meningitis. Tuberculosis infection cannot be separated from nutritional status.
John Patria Maruli Sinaga, Nelly Amalia Risan, Uni Gamayani   +2 more
doaj   +1 more source

Mechanism, spectrum, consequences and management of hyponatremia in tuberculous meningitis [version 1; peer review: 2 approved]

Wellcome Open Research, 2019
Hyponatremia is the commonest electrolyte abnormality in hospitalized patients and is associated with poor outcome. Hyponatremia is categorized on the basis of serum sodium into severe (< 120 mEq/L), moderate (120-129 mEq/L) and mild (130-134mEq/L ...
Usha K. Misra, Jayantee Kalita, Tuberculous Meningitis International Research Consortium   +2 more
doaj   +1 more source

Spectrum of central nervous system infections in neurosciences hospital in two years : a retrospective study

مجله كليه طب الكندي, 2020
Background :Infectious disorders in general have high morbidity and mortality.. CNS infections include many disorders like bacterial meningitis, tuberculous and other subacute and chronic meningitis, viral meningitis, cerebral abscess, spinal cord ...
Aiyar Shakir Jawad
doaj   +1 more source

Protective effect of neonatal BCG vaccines against tuberculous meningitis

Biomolecules & Biomedicine, 2004
Neonatal BCG vaccination reduces the risk of tuberculosis and provides protection higher than 80% against the development of meningeal and miliary tuberculosis in newborns.
Sandra Puvacić, Jadranka Dizdarević, Z. Santić, M. Mulaomerović   +3 more
doaj   +1 more source

Tuberculous Meningitis in Children: Reducing the Burden of Death and Disability

Pathogens, 2021
Tuberculous meningitis disproportionately affects young children. As the most devastating form of tuberculosis, it is associated with unacceptably high rates of mortality and morbidity even if treated.
Julie Huynh, Yara-Natalie Abo, Karen du Preez, Regan Solomons, Kelly E Dooley, James A Seddon   +5 more
doaj   +1 more source

TUBERCULOUS MENINGITIS [PDF]

The Journal of Nervous and Mental Disease, 1922
n ...
openaire   +1 more source

CLINICAL SPECTRUM AND OUTCOME OF PATIENTS WITH TUBERCULOUS MENINGITIS AT A TERTIARY CARE HOSPITAL OF PAKISTAN

Pakistan Armed Forces Medical Journal, 2021
Objective: To assess the clinical profile and outcome of patients admitted with the diagnosis of tuberculous meningitis (TBM) at neurology unit of a tertiary care teaching hospital of Pakistan. Study Design: Cross-sectional study.
Atifa Gilani, Zahid Hassan, Khurram Haq Nawaz, Muhammad Babar Khan, Saeed Arif, Sakhawat Kazmi   +5 more
doaj   +1 more source