CSF Proteins as Discreminatory Markers of Tubercular and Pyogenic Meningitis [PDF]
Introduction: Meningitis is still a major cause of illness in many parts of the world. Though substantial improvement has been occurred in the diagnosis of meningitis, conclusive differentiation between tubercular and pyogenic meningitis remains to ...
Ravi Shekhar +3 more
doaj +1 more source
Molecular epidemiology of tuberculous meningitis isolates from Thailand: a collective summary
Background Tuberculosis infection of meninges or tuberculous meningitis is an important serious form of Mycobacerium tuberculosis infection. This nervous system infection can lead to complex clinical problem.
Beuy Joob, Viroj Wiwanitkit
doaj +1 more source
Diagnostic accuracy of Xpert MTB/RIF Ultra for tuberculous meningitis in HIV-infected adults: a prospective cohort study. [PDF]
BACKGROUND: WHO recommends Xpert MTB/RIF as initial diagnostic testing for tuberculous meningitis. However, diagnosis remains difficult, with Xpert sensitivity of about 50-70% and culture sensitivity of about 60%.
ASTRO-CM Trial Team +12 more
core +1 more source
Intracranial tuberculous mass lesions treated with thalidomide in an immunocompetent child from a low tuberculosis endemic country: A case report [PDF]
Rationale: Tuberculous meningitis is a highly morbid, often fatal disease. Patient concern: We describe a case of an Italian child. Diagnoses: we diagnosed early a Tuberculous meningitis complicated by the occurrence of hydrocephalus, stroke, and ...
Ajassa, Camilla +8 more
core +1 more source
Quantitative proteomics for identifying biomarkers for tuberculous meningitis
Introduction Tuberculous meningitis is a frequent extrapulmonary disease caused by Mycobacterium tuberculosis and is associated with high mortality rates and severe neurological sequelae.
Kumar Ghantasala S Sameer +16 more
doaj +1 more source
Extensive vasculitis in tuberculous meningitis
Tuberculous meningitis causes substantial morbidity and mortality in tropical countries. The various complications reported are hydrocephalus, vasculitic infarcts, tuberculomas, abscesses, and optochiasmatic arachnoiditis.
Rajesh Verma, Rajarshi Chakraborty
doaj +1 more source
Immunological diagnosis as an adjunctive tool for an early diagnosis of tuberculous meningitis of an immune competent child in a low tuberculosis endemic country: A case report [PDF]
Background: Pediatric tuberculous meningitis is a highly morbid, often fatal disease. Its prompt diagnosis and treat - ment saves lives, in fact delays in the initiation of therapy have been associated with high mortality rates. Case presentation:
Ajassa, Camilla +12 more
core +4 more sources
Undernutrition as Risk Factor of Hydrocephalus Prevalence in Children with Tuberculous Meningitis
Background: Hydrocephalus is the most frequent neurological complication in children with tuberculous meningitis. Tuberculosis infection cannot be separated from nutritional status.
John Patria Maruli Sinaga +2 more
doaj +1 more source
Genotype-stratified adjunctive dexamethasone for tuberculous meningitis in HIV-negative adults: a randomized controlled phase 3 trial. [PDF]
Donovan J +26 more
europepmc +2 more sources
Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis. [PDF]
BACKGROUND: Central nervous system tuberculosis (CNS-TB) may be fatal even with treatment. Neutrophils are the key mediators of TB immunopathology, and raised CSF matrix metalloproteinase-9 (MMP-9) which correlates to neutrophil count in CNS-TB is ...
Brilha, S +6 more
core +1 more source

