Results 21 to 30 of about 178,050 (257)

Role of Cerebrospinal Fluid Lactate and C-Reactive Protein in Differential Diagnosis of Meningitis in Adults [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Differentiating various types of meningitis is still a challenge as yield of microbiological tests are generally low in these disorders. Aim: To find out the role of Cerebrospinal Fluid (CSF) lactate and CSF C-reactive Protein (CRP) for the
Pediakkal M Jabir, V Valappil Ashraf, Thekkedath Manojan   +2 more
doaj   +1 more source

A Diagnostic Formula for Discrimination of Tuberculous and Bacterial Meningitis Using Clinical and Laboratory Features

Frontiers in Cellular and Infection Microbiology, 2020
Background: The discrimination of tuberculous meningitis and bacterial meningitis remains difficult at present, even with the introduction of advanced diagnostic tools.
Yun Yang, Xin-Hui Qu, Kun-Nan Zhang, Xiao-Mu Wu, Xin-Rong Wang, An Wen, Ling-Juan Li   +6 more
doaj   +1 more source

Plasma Pharmacokinetics of High-Dose Oral versus Intravenous Rifampicin in Patients with Tuberculous Meningitis: a Randomized Controlled Trial

medRxiv, 2021
Higher doses of intravenous rifampicin may improve outcomes in tuberculous meningitis but are impractical in high-burden settings. We hypothesized that plasma rifampicin exposures would be similar between oral dosing of 35 mg/kg of body weight and ...
S. Wasserman, A. Davis, C. Stek, M. Chirehwa, S. Botha, R. Daroowala, Marise Bremer, M. Maxebengula, Sonya Koekemoer, R. Goliath, A. Jackson, T. Crede, J. Naudé, P. Szymanski, Y. Vallie, M. S. Moosa, L. Wiesner, J. Black, G. Meintjes, G. Maartens, R. Wilkinson   +20 more
semanticscholar   +1 more source

Defeating Paediatric Tuberculous Meningitis: Applying the WHO “Defeating Meningitis by 2030: Global Roadmap”

Microorganisms, 2021
Children affected by tuberculous meningitis (TBM), as well as their families, have needs that lie at the intersections between the tuberculosis and meningitis clinical, research, and policy spheres.
R. Basu Roy, S. Bakeera-Kitaka, C. Chabala, D. Gibb, J. Huynh, H. Mujuru, N. Sankhyan, J. Seddon, Suvasini Sharma, Varinder Singh, E. Wobudeya, S. Anderson   +11 more
semanticscholar   +1 more source

Tuberculous Meningitis: Impact of Timing of Treatment Initiation on Mortality

Open Forum Infectious Diseases, 2021
We conducted a retrospective cross-sectional study of adult hospitalized patients with confirmed tuberculous meningitis to determine the impact of the timing of treatment initiation on mortality.
Jaime Soria, A. Chiappe, J. Gallardo, J. Zunt, A. Lescano   +4 more
semanticscholar   +1 more source

CSF Proteins as Discreminatory Markers of Tubercular and Pyogenic Meningitis [PDF]

Journal of Clinical and Diagnostic Research, 2013
Introduction: Meningitis is still a major cause of illness in many parts of the world. Though substantial improvement has been occurred in the diagnosis of meningitis, conclusive differentiation between tubercular and pyogenic meningitis remains to ...
Ravi Shekhar, J. Rama Rao, K. Ambika Devi, R Babu Rao   +3 more
doaj   +1 more source

Tuberculous Meningitis: Pathogenesis, Immune Responses, Diagnostic Challenges, and the Potential of Biomarker-Based Approaches

Journal of Clinical Microbiology, 2020
Tuberculous meningitis (TBM) is the most devastating form of tuberculosis (TB), causing high mortality or disability. Clinical management of the disease is challenging due to limitations of the existing diagnostic approaches.
Charles M. Manyelo, R. Solomons, G. Walzl, N. Chegou   +3 more
semanticscholar   +1 more source

Child with tuberculous meningitis and COVID-19 coinfection complicated by extensive cerebral sinus venous thrombosis

BMJ Case Reports, 2020
We herein report a case of a child with tuberculous meningitis and COVID-19 coinfection complicated by hydrocephalus, arterial ischaemic stroke and extensive cerebral sinus venous thrombosis.
F. Essajee, R. Solomons, P. Goussard, R. van Toorn   +3 more
semanticscholar   +1 more source

TUBERCULOUS MENINGITIS [PDF]

The Journal of Nervous and Mental Disease, 1922
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openaire   +2 more sources

Quantitative proteomics for identifying biomarkers for tuberculous meningitis

Clinical Proteomics, 2012
Introduction Tuberculous meningitis is a frequent extrapulmonary disease caused by Mycobacterium tuberculosis and is associated with high mortality rates and severe neurological sequelae.
Kumar Ghantasala S Sameer, Venugopal Abhilash K, Mahadevan Anita, Renuse Santosh, Harsha H C, Sahasrabuddhe Nandini A, Pawar Harsh, Sharma Rakesh, Kumar Praveen, Rajagopalan Sudha, Waddell Keith, Ramachandra Yarappa L, Satishchandra Parthasarathy, Chaerkady Raghothama, Prasad T S Keshava, Shankar K, Pandey Akhilesh   +16 more
doaj   +1 more source