Results 51 to 60 of about 29,629 (267)

Cerebrospinal fluid cytokines and matrix metalloproteinases in human immunodeficiency seropositive and seronegative patients of tuberculous meningitis

open access: yesAnnals of Indian Academy of Neurology, 2014
Background: Some important clinical differences exist between human immunodeficiency virus (HIV)-seropositive and HIV-seronegative patients. Alterations in the cerebrospinal fluid (CSF) cytokines and matrix metalloproteinase have been noted in ...
Dheeraj Rai   +9 more
doaj   +1 more source

Comparison of clinical and CSF profiles in children with tuberculous and pyogenic meningitis; role of CSF protein: Glucose ratio as diagnostic marker of tuberculous meningitis [PDF]

open access: yes, 2013
Objectives: To compare the clinical and laboratory features of tuberculous meningitis with bacterial meningitis and to determine if protein glucose ratio in the cerebrospinal fluid can be predictive of the condition.Methods: It was a retrospective ...
Humayun, Khadija   +3 more
core   +1 more source

Exploring Aspartate Transcarbamoylase: A Promising Broad‐Spectrum Target for Drug Development

open access: yesChemBioChem, EarlyView.
Pyrimidine biosynthesis is a pivotal process shared by both eukaryotes and prokaryotes. This review examines the applications and advantages of a series of inhibitors specifically designed to target aspartate transcarbamylase within the de novo biosynthetic pathway of the malarial parasite.
Siyao Chen   +8 more
wiley   +1 more source

Hydrocephalus Caused by Tuberculous Meningitis in an Immunocompetent Young Adult: A Case Report

open access: yesInternational Medical Case Reports Journal, 2023
Rizaldy Taslim Pinzon,1,2 Vanessa Veronica1 1Faculty of Medicine, Duta Wacana Christian University, Yogyakarta, Indonesia; 2Department of Neurology, Bethesda Hospital, Yogyakarta, IndonesiaCorrespondence: Rizaldy Taslim Pinzon, Duta Wacana Christian ...
Pinzon RT, Veronica V
doaj  

Pregnancy-Related Tuberculous Meningitis and Immune Reconstitution Inflammatory Syndrome: A Case Series and Systematic Review [PDF]

open access: yes, 2022
Background: Tuberculosis is a leading cause of death among women of reproductive age. However, tuberculous meningitis, the most severe form of extrapulmonary tuberculosis, is rarely discussed in pregnancy despite this being a unique period of immune ...
Bahr, NC   +10 more
core  

Evidence of Pellagra on 19th Century Human Crania From Northern Italy by Combining Stable Isotope and Paleopathological Analyses

open access: yesInternational Journal of Osteoarchaeology, EarlyView.
ABSTRACT Pellagra is a disease caused by a nutritional deficiency, with fatal outcome due to multiple‐organ failure, that affected European rural areas until the early decades of the 20th century, especially Veneto region (Italy). At the skeletal level, previous studies pointed out that pathological signs left by the disease are generic and typical of ...
Nicola Carrara   +8 more
wiley   +1 more source

Diffuse Tuberculous Cerebritis in Immunocompetent Hosts-An Uncommon Entity [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2019
Central Nervous System (CNS) tuberculosis is a common disease in developing countries with varied presentation, the most common being tuberculous meningitis.
Animesh Das, Sunil Pradhan
doaj   +1 more source

Pathomorphosis of Extrapulmonary Tuberculosis in Children [PDF]

open access: yes, 2016
Aim. To study clinical and epidemiological aspects of pathomorphosis of extrapulmonary tuberculosis clinical forms.Materials and Methods. Retrospective analysis of 138 case histories in children aged to 15 years, obtaining extrapulmonary tuberculosis ...
Mykolyshyn, L. (Lidia)   +1 more
core   +2 more sources

Central nervous system tuberculosis in Western Sydney: a 10‐year retrospective cohort study

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Central nervous system tuberculosis (CNS‐TB) is a rare complication of tuberculosis. There is a lack of data surrounding investigation and management of this in Australia. Aim To review CNS‐TB cases in Western Sydney, Australia, and understand the epidemiology, investigation, diagnosis, management and outcomes in a low‐prevalence ...
Hayden Zhang   +5 more
wiley   +1 more source

Tuberculous meningitis.

open access: yesJournal of neurology, neurosurgery, and psychiatry, 2000
Uncertainty and doubt dominate all aspects of tuberculous meningitis (TBM). The variable natural history and accompanying clinical features of TBM hinders the diagnosis. Ziehl-Neelsen staining lacks sensitivity and culture results are often insufficiently timely to aid clinical judgement.
Thwaites, G   +5 more
openaire   +2 more sources

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