Results 81 to 90 of about 35,325 (274)

Neutrophil-Associated Central Nervous System Inflammation in Tuberculous Meningitis Immune Reconstitution Inflammatory Syndrome.

, 2014
Background. The immunopathogenesis of tuberculosis-associated immune reconstitution inflammatory syndrome (IRIS) remains incompletely understood, and we know of only 1 disease site-specific study of the underlying immunology; we recently showed that ...
Coussens, AK, Deffur, A, Ismail, Z, Lesosky, M, Marais, S, Meintjes, G, Pepper, DJ, Schutz, C, Wilkinson, KA, Wilkinson, RJ   +9 more
core   +1 more source

Clinical Features and Genetic Analysis of 20 Chinese Patients with X-Linked Hyper-IgM Syndrome [PDF]

, 2014
X-linked hyper-IgM syndrome (XHIGM) is one type of primary immunodeficiency diseases, resulting from defects in the CD40 ligand/CD40 signaling pathways. We retrospectively analyzed the clinical and molecular features of 20 Chinese patients diagnosed and ...
Chen, Tong-Xin, Tian, Zhi-Qing, Wang, Lin-Lin, Wang, Wei-Fan, Wang, Xiao-Fang, Zhao, Wei, Zhou, Wei   +6 more
core   +4 more sources

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, Volume 21, Issue 29, July 24, 2025.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Anti-tuberculosis therapy combined with ventriculoperitoneal shunt for tuberculous meningitis combined with hydrocephalus: A case report

Journal of Infection and Public Health
Tuberculous meningitis is a severe and potentially life-threatening form of central nervous system tuberculosis. Hydrocephalus is a critical complication and risk factor for the high mortality of tuberculous meningitis, exacerbating neurological damage ...
Chengmin Sheng, Mengqi Wang, Qiongling Bao, Wanru Guo, Hongxin Fu, Xiaomeng Li, Chenxia Zhang, Kaijin Xu   +7 more
doaj   +1 more source

Deep‐Learning Model for Central Nervous System Infection Diagnosis and Prognosis Using Label‐Free 3D Immune‐Cell Morphology in the Cerebrospinal Fluid

Advanced Intelligent Systems, Volume 7, Issue 6, June 2025.
Early diagnosis and prognosis prediction of central nervous system infections are critical. This study introduces a deep‐learning model utilizing cerebrospinal fluid immune‐cell morphology captured via 3D holotomography. The model effectively predicts infection etiology and prognosis, achieving high accuracy.
Bo Kyu Choi, Ho Heon Yang, Jong Hyun Kim, JaeSeong Hong, Kyung Min Kim, Yu Rang Park   +5 more
wiley   +1 more source

Evaluation of Geno Type MTBDRplus Line Probe Assay for Early Detection of Drug Resistance in Tuberculous Meningitis Patients in India

Journal of Global Infectious Diseases, 2015
Background: Molecular methods which allow for rapid and reliable detection of drug resistance have yet not been sufficiently evaluated for timely management of patients with tuberculous meningitis.
Renu Gupta, Rajeev Thakur, Prerna Gupta, Nupur Jalan, Suman Kushwaha, Meena Gupta, Piyush Gupta, Amitesh Aggarwal, Vikas Manchanda   +8 more
doaj   +1 more source

Prognostic indicators in patients with intracranial tuberculoma: a review of 102 cases [PDF]

, 2004
Objective: To see the characteristics, course and outcome of patients suffering from intracranial tuberculoma. Methods: Retrospective review of 102 patients diagnosed as intracranial tuberculoma at a tertiary care center over 10 years.
Khealani, Bhojo A., Moolani, M. K., Sarwari, A. R., Smego, R. A., Wasay, Mohammad, Zaheer, J.   +5 more
core   +1 more source

Bilateral cortical blindness secondary to tuberculous meningitis in a young Indian female [PDF]

, 2013
non
Anil Gurtoo, Meenakshi wadhwani, Rajiv Garg   +2 more
core  

Myelitis: A Common Complication of Tuberculous Meningitis Predicting Poor Outcome [PDF]

, 2022
Yuxuan Jiang, Xiangqin Xu, Zhuoxin Guo, Yuxin Liu, Jiahao Lin, Lijun Suo, Ying Jiang, Bo Liu, Tingting Lü   +8 more
openalex   +1 more source

Single‐Cell Metabolic Labeling Probe for Diagnosing Tuberculous Meningitis: A Case Report

iLABMED, Volume 3, Issue 2, Page 201-205, June 2025.
This study reports the first clinical use of a single‐cell metabolic labeling probe for tuberculosis for diagnosing tuberculous meningitis, which rapidly and accurately detected Mycobacterium tuberculosis in cerebrospinal fluid. The patient's satisfactory therapeutic outcome highlights single‐cell metabolic labeling probe for tuberculosis's potential ...
Jiahao Wang, Guiqin Dai, Pengfei Zhao, Mingbin Zheng, Li Wei, Hongzhou Lu   +5 more
wiley   +1 more source