Results 81 to 90 of about 178,050 (257)

Latest Progress on Tuberculosis and HIV Co‐Infection: A Closer Look at People of Different Ages

open access: yesAdvanced Therapeutics, Volume 8, Issue 4, April 2025.
Tackling the problem of tuberculosis (TB) and human immunodeficiency virus (HIV) co‐infection is a serious global health concern affecting people of all ages. This review presents the characteristics of both diseases, current treatment and diagnostic guidelines, associated problems, innovations in disease management, and overall effects on global ...
Anna Yusuf Aliyu, Oluwatoyin A. Adeleke
wiley   +1 more source

Exploring Aspartate Transcarbamoylase: A Promising Broad‐Spectrum Target for Drug Development

open access: yesChemBioChem, Volume 26, Issue 7, April 1, 2025.
Pyrimidine biosynthesis is a pivotal process shared by both eukaryotes and prokaryotes. This review examines the applications and advantages of a series of inhibitors specifically designed to target aspartate transcarbamylase within the de novo biosynthetic pathway of the malarial parasite.
Siyao Chen   +8 more
wiley   +1 more source

Clinical Characteristics of Miliary Pulmonary Tuberculosis in Pregnancy After In Vitro Fertilization‐Embryo Transfer: A Retrospective Clinical Study

open access: yesHealth Science Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background and Aims Miliary pulmonary tuberculosis (MPTB) is rare in patients treated with In Vitro fertilization‐embryo transfer (IVF‐ET), and can be life‐threatening to pregnant women and fetuses. We aimed to describe the clinical characteristics of MPTB after IVF‐ET and pregnancy outcomes to provide reference for early diagnosis and ...
Litao Guo, Xiaoling Wu, Lin Cao
wiley   +1 more source

Circulating Growth Differentiation Factor 15 (GDF15) in Paediatric Disease: A Systematic Review

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 2, April 2025.
ABSTRACT Background Growth Differentiation Factor 15 (GDF15), a nonspecific inflammatory marker and member of the TGF‐β superfamily, has a well‐established role in both inflammation and metabolic modulation, but lacks a comprehensive paediatric literature review.
David W. Kronenberger   +3 more
wiley   +1 more source

Lateral Transorbital Approach for Lateral Sphenoid Defects: Anatomy, Surgery, Nasoseptal Flap Use, and a 4‐Case Series

open access: yesLaryngoscope Investigative Otolaryngology, Volume 10, Issue 2, April 2025.
In this case series, we assess the effectiveness and anatomical advantages of the lateral transorbital approach for complex skull base repairs in the lateral recess of a pneumatized sphenoid sinus and compare it to standard transnasal methods. We conclude that the lateral transorbital approach enhances visualization, reduces nerve injury risk, and ...
Darlene Lubbe   +2 more
wiley   +1 more source

Epidemiology of concurrent extrapulmonary tuberculosis in inpatients with extrapulmonary tuberculosis lesions in China: a large-scale observational multi-centre investigation

open access: yesInternational Journal of Infectious Diseases, 2022
: Aims: A high proportion of all patients with tuberculosis (TB) present with extrapulmonary TB (EPTB), including concurrent EPTB involving more than one extrapulmonary lesion site.
Wanli Kang   +56 more
doaj  

Mortality in hospitalized patients with tuberculous meningitis

open access: yesBMC Infectious Diseases, 2019
BackgroundTo evaluate the mortality in hospitalized patients with tuberculous meningitis and describe factors associated with an increased risk of mortality.MethodsRetrospective study of hospitalized patients with tuberculous meningitis between 2006 and ...
Jaime Soria   +7 more
semanticscholar   +1 more source

Evidence of Pellagra on 19th Century Human Crania From Northern Italy by Combining Stable Isotope and Paleopathological Analyses

open access: yesInternational Journal of Osteoarchaeology, Volume 35, Issue 2, March/April 2025.
ABSTRACT Pellagra is a disease caused by a nutritional deficiency, with fatal outcome due to multiple‐organ failure, that affected European rural areas until the early decades of the 20th century, especially Veneto region (Italy). At the skeletal level, previous studies pointed out that pathological signs left by the disease are generic and typical of ...
Nicola Carrara   +8 more
wiley   +1 more source

Secondary hypertension: A rare cause

open access: yesIndian Journal of Endocrinology and Metabolism, 2011
A 13-year-old, previously asymptomatic girl was admitted with features of tuberculous meningitis. She was found to be hypertensive and further investigations revealed an extra-adrenal paraganglioma.
Mary Grace   +3 more
doaj   +1 more source

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