Working with Miraculous Mice: Mus musculus as a Model Organism
Abstract The laboratory mouse has been described as a “miracle” model organism, providing a window by which we may gain an understanding of ourselves. Since the first recorded mouse experiment in 1664, the mouse has become the most used animal model in biomedical research.
Anick Standley +4 more
wiley +1 more source
Targeting TLR2 for Vaccine Development
Novel and more effective immunization strategies against many animal diseases may profit from the current knowledge on the modulation of specific immunity through stimulation of innate immune receptors. Toll‐like receptor (TLR)2‐targeting formulations, such as synthetic lipopeptides and antigens expressed in fusion with lipoproteins, have been shown to
Afonso P. Basto +2 more
wiley +1 more source
T-cell epitopes of the major peach allergen, Pru p 3: Identification and differential T-cell response of peach-allergic and non-allergic subjects [PDF]
Lipid transfer proteins (LTPs), particularly peach Pru p 3, are the most relevant plant food allergens in the South of Europe, and, therefore, their allergic properties have been extensively studied.
Tordesillas Villuendas, Leticia +17 more
core +1 more source
Stability of the Bet v 1 cross-reactive allergens Api g 1 and Dau c 1 : a biophysical approach [PDF]
The allergen Bet v 1 is known as the primary sensitizer for birch pollen-related food allergy and is responsible for IgE cross-reactivity to pathogenesis-related 10 (PR-10) proteins from, in particular, fruits from the Rosaceae and vegetables from the ...
Bollen, M.A.
core
Identification of Antigens Specific to Non-Tuberculous Mycobacteria: The Mce Family of Proteins as a Target of T Cell Immune Responses [PDF]
The lack of an effective TB vaccine hinders current efforts in combating the TB pandemic. One theory as to why BCG is less protective in tropical countries is that exposure to non-tuberculous mycobacteria (NTM) reduces BCG efficacy.
Willem A Hanekom +36 more
core +1 more source
Management of intracranial tuberculous mass lesions: How long should we treat for? [PDF]
Tuberculous intracranial mass lesions are common in settings with high tuberculosis (TB) incidence and HIV prevalence. The diagnosis of such lesions, which include tuberculoma and tuberculous abscesses, is often presumptive and based on radiological ...
Van Toorn, R +10 more
core +1 more source
Efficiency of screening for tuberculous infection among children in Tatarstan Republic
Goal of the study: to investigate the role of skin test with tuberculous recombinant allergen (TRA) in mass screening for tuberculosis in children from high risk groups in Tatarstan Republic.Materials and methods.
R. Kh. Fatykhova, A. P. Aleks
doaj +1 more source
The significance of lipoarabinomannan (LAM) level in blood serum for the confirmation of tuberculosis was analyzed in 106 patients at the advanced stages of HIV infection.
A. V. Dudchenko +2 more
doaj +1 more source
INFLUENCE OF HLA-DRB1* ALLELIC SETS ON THE DEVELOPMENT OF TUBERCULOSIS IN CHILDREN
According to the WHO data, tuberculosis still represents a serious public health problem worldwide. Deterioration of socio-economic conditions in the population complicates epidemic situation for tuberculosis inRussia, thus leading to increase in acute ...
A. A. Starshinova +5 more
doaj +1 more source
Long-term periodic anthelmintic treatments are associated with increased allergen skin reactivity. [PDF]
BACKGROUND: The low prevalence of allergic disease in the rural tropics has been attributed to the protective effects of chronic helminth infections. There is concern that treatment-based control programmes for these parasites may lead to an increase in ...
Oviedo, G +24 more
core +1 more source

