Results 51 to 60 of about 1,087,479 (281)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Kemungkinan Penggunaan Bambu Sebagai Wadah Pada Masyarakat Ulu Leang I
Berkala Arkeologi, 1991 Melihat banyaknya jenis bambu yang tumbuh di Indonesia, sangatlah mungkin bahwa berbagai jenis bambu telah dimanfaatkan oleh masyarakat Indonesia sejak masa prasejarah.
Muhammad Hidayat
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Reporting Nasogastric Tube ‘in the Stomach’ Is Not Enough: Full Intragastric Positioning Matters
Journal of the Belgian Society of RadiologyTeaching point: Even when the nasogastric tube (NGT) tip appears intragastric on chest radiography, malposition of proximal side holes above the gastro‑oesophageal junction may result in clinically significant aspiration.
Thalinne Schueremans, Nico Hustings
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Determination of the Optimal Reduction Ratio for Least Springback during Cold Drawing of Seamless Tubes [PDF]
Journal of Applied and Computational Mechanics, 2018 Cold drawing process is one of the most used metals forming processes in industries for forming seamless tubes. This process of plastic deformation of metals occurs below the recrystallization temperature and is generally performed at room temperature ...
D. Karanjule, S. Bhamare, T. Rao
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Structure, 2010 High quality images of microtubules with different numbers of protofilaments, and hence substantially different curvatures, have been reconstructed from electron microscopy (EM) data (Sui and Downing, 2010). The data show how three versatile loops that mediate lateral interactions allow microtubules to be strong without being brittle.
openaire +2 more sources