Results 61 to 70 of about 1,958,086 (308)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
, 2018 We present a theory for the three-dimensional evolution of tubes with expandable walls conveying fluid. Our theory can accommodate arbitrary deformations of the tube, arbitrary elasticity of the walls, and both compressible and incompressible flows ...
Gay-Balmaz, François +1 more
core +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Effect of local induction heating on secondary roll-forming of high strength square tubes
工程科学学报, 2016 The formability of corners was improved by heating the corner area of high strength square tubes with induction coils.Under the premise of not impacting the undeformed zone,we obtained the ideal sectional dimension,microstructure and properties of ...
PENG Xue-feng +5 more
doaj +1 more source
In Vitro Evaluation of Eslicarbazepine Delivery via Enteral Feeding Tubes [PDF]
, 2017 Purpose: The feasibility of preparing an eslicarbazepine acetate suspension using Aptiom tablets for administration via enteral feeding tubes was evaluated.
Dave, Vivek S +3 more
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Indian Journal of OphthalmologyGlaucoma drainage devices are invaluable in the management of secondary/ refractory glaucomas. This study aimed to compare the efficacy and safety of Aurolab Aqueous Drainage Implant (AADI) and the Ahmed Glaucoma Valve (AGV) in filtration-surgery-naïve ...
Vanita Pathak-Ray
doaj +1 more source
Influence of tubes curve on energy delivering in bonding region during explosive welding
Vojnotehnički Glasnik, 1998 Explosively welded axisymmetric components generally in the tubular cylindrical form, vary from mono and multi-metallic duplex and triplex cylinders, through other systems, to materially and geometrically sophisticated composites.
Vlado Radić
doaj +1 more source
Experimental and numerical study on axial crushing behaviour of pultruded composite tubes [PDF]
, 2008 An extensive experimental investigation was carried out to study the energy absorbing characteristics and progressive deformation behavior of unidirectional pultruded composite tubes subjected to an axial impact load.
De Wolf, Kathleen +8 more
core +1 more source