Results 301 to 310 of about 286,999 (386)

Repair of injured proximal tubule does not involve specialized progenitors

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2011
B. Humphreys   +5 more
semanticscholar   +1 more source

Tissue‐Specific Regulation of Fatty Acid Metabolism in a Mouse Model of Isolated Complex I Deficiency

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Isolated complex I deficiency (ICD) is commonly associated with mitochondrial diseases and closely mimics subacute necrotising encephalomyelopathy. This disorder is characterised by metabolic perturbations that affect energy metabolism pathways, including fatty acid metabolism.
Sibonelo Glen Khumalo   +2 more
wiley   +1 more source

Multi-omic and spatial analysis of mouse kidneys highlights sex-specific differences in gene regulation across the lifespan. [PDF]

open access: yesNat Genet
Chen S   +23 more
europepmc   +1 more source

The Omics‐Driven Machine Learning Path to Cost‐Effective Precision Medicine in Chronic Kidney Disease

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Chronic kidney disease (CKD) poses a significant and growing global health challenge, making early detection and slowing disease progression essential for improving patient outcomes. Traditional diagnostic methods such as glomerular filtration rate and proteinuria are insufficient to capture the complexity of CKD.
Marta B. Lopes   +9 more
wiley   +1 more source

SGLT2 mediates glucose reabsorption in the early proximal tubule

open access: yesJournal of the American Society of Nephrology, 2010
V. Vallon   +5 more
semanticscholar   +1 more source

Urinary Proteomics and Systems Biology Link Eight Proteins to the Higher Risk of Hypertension and Related Complications in Blacks Versus Whites

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Blacks are more prone to salt‐sensitive hypertension than Whites. This cross‐sectional analysis of a multi‐ethnic cohort aimed to search for proteins potentially involved in the susceptibility to salt sensitivity, hypertension, and hypertension‐related complications.
De‐Wei An   +22 more
wiley   +1 more source

Investigation of the Urinary Peptidome to Unravel Collagen Degradation in Health and Kidney Disease

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Naturally occurring fragments of collagen type I alpha 1 chain (COL1A1) have been previously associated with chronic kidney disease (CKD), with some fragments showing positive and others negative associations. Using urinary peptidome data from healthy individuals (n = 1131) and CKD patients (n = 5585) this aspect was investigated in detail ...
Ioanna K. Mina   +7 more
wiley   +1 more source

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