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Autophagy Related 5 Promotes Mitochondrial Fission and Inflammation via HSP90-HIF-1α-Mediated Glycolysis in Kidney Fibrosis. [PDF]

Adv Sci (Weinh)
Hu Y, Li J, Chen H, Shi Y, Ma X, Wang Y, Li X, Zhong Q, Wang Y, Jiang D, Zhuang S, Liu N.   +11 more
europepmc   +1 more source

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Transporters and tubule crystals in the insect Malpighian tubule

Current Opinion in Insect Science, 2021
The insect renal (Malpighian) tubules are functionally homologous to the mammalian kidney. Accumulating evidence indicates that renal tubule crystals form in a manner similar to mammalian kidney stones. In Drosophila melanogaster, crystals can be induced by diet, toxic substances, or genetic mutations that reflect circumstances influencing or eliciting
Michael F. Romero, Carmen J. Reynolds, Daniel R. Turin   +2 more
openaire   +3 more sources

Malpighian tubules in harvestmen

Protoplasma, 2021
In arachnids, the Malpighian tubules (MTs), coxal glands and stercoral pockets are capable of collecting and removing excreta from the body. The presence of the MTs among Opiliones was evidenced for the first time in Amilenus aurantiacus in 2015. Individuals undergo a winter diapause subterranean habitats.
Lipovšek Delakorda, Saška, Kozel, Peter, Leitinger, Gerd, Novak, Tone   +3 more
openaire   +4 more sources

Zigzag Lipid Tubules

The Journal of Physical Chemistry B, 2008
We report a method based on poly(dimethylsiloxane) (PDMS) stamp-assisted moving contact line to bend lipid tubules into zigzags on glass substrates. Atomic force microscopy (AFM) reveals that the zigzag lipid tubules buckle at the bent sites. The measurements of buckling heights as a function of bending angles suggest a gradual buckling mode.
Zhao, Yue, Fang, Jiyu
openaire   +4 more sources

Distal Convoluted Tubule

Comprehensive Physiology, 2015
AbstractThe distal convoluted tubule (DCT) is a short nephron segment, interposed between the macula densa and collecting duct. Even though it is short, it plays a key role in regulating extracellular fluid volume and electrolyte homeostasis. DCT cells are rich in mitochondria, and possess the highest density of Na+/K+‐ATPase along the nephron, where ...
James A. McCormick, David H. Ellison
openaire   +3 more sources

Fabrication of Protein Tubules:  Immobilization of Proteins on Peptide Tubules

The Journal of Physical Chemistry B, 2001
Peptide tubules, self-assemblies of bis(N-α-amido-glycylglycine)-1,7-heptane dicarboxylate, were functionalized by poly(l-lysine), d-biotin, avidin, and albumin bovine. Proteins were covalently immobilized on the peptide tubules via NHS ester intermediates, while amide groups of the peptide tubules were also capable of intercalating proteins via ...
Gary E. Douberly, Su Pan, and Deron Walters, Hiroshi Matsui   +3 more
openaire   +3 more sources

Melting of Phospholipid Tubules

Physical Review Letters, 1996
The melting of lipid-based microcylinders (tubules) has been investigated for systems with single and multiple bilayer walls using high field, magnetic birefringence, and precision microcalorimetry. The pretransitional behavior of both the magnetic birefringence and the specific heat is very different in tubules with a single bilayer wall from that of ...
George Nounesis, Alok Singh, Banahalli R. Ratna, Roger S. Flugel, Sung-Tae Shin, Samuel Sprunt, Ranganathan Shashidhar, Satyendra Kumar, J. D. Litster   +8 more
openaire   +3 more sources

Nanocapillarity in fullerene tubules

Physical Review Letters, 1992
Fullerene tubules are shown to be highly polarizable ``molecular straws'' capable of ingesting dipolar molecules. Local-density-functional calculations on HF molecules within a finite-length tubule, of size 144 atoms, demonstrate this effect. The energy of incarceration is several times the thermal ambient at room temperature.
Mark R. Pederson, Jeremy Q. Broughton
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Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment.

Integrative Biology, 2013
Kidney toxicity is one of the most frequent adverse events reported during drug development. The lack of accurate predictive cell culture models and the unreliability of animal studies have created a need for better approaches to recapitulate kidney ...
Kyung-Jin Jang, A. P. Mehr, G. Hamilton, L. McPartlin, Seyoon Chung, K. Suh, D. Ingber   +6 more
semanticscholar   +1 more source