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Diagnostic uncertainty of tumefactive cystic demyelinating lesions.
Neurosciences (Riyadh, Saudi Arabia), 2013 Dhaifallah M, Almalki +3 more
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Tumefactive demyelinating lesions
Neuroradiology, 1996We studied 21 cases of pathologically confirmed tumefactive demyelinating lesions and reviewed the spectrum of tumefactive demyelinating lesions in the literature. Radiological features and clinical data were reviewed to characterize the lesions as consistent with a known demyelinating disease, most notably multiple sclerosis.
A P, Dagher, J, Smirniotopoulos
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Tumefactive demyelinating lesions: A comprehensive review
Multiple Sclerosis and Related Disorders, 2017Tumefactive multiple sclerosis or tumefactive demyelinating lesion (TDL) is one of the rare variants of multiple sclerosis (MS) posing a diagnostic challenge and a therapeutic enigma since it is difficult to distinguish from a true central nervous system (CNS) neoplasm or other CNS lesions on magnetic resonance imaging (MRI).
Hussein, Algahtani +2 more
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Tumefactive demyelinating lesions in children
European Journal of Paediatric NeurologyTumefactive lesions (TDL) are larger than 2 cm in diameter on T2-weighted brain MRI. They are distinguished from other types of demyelinating lesions by their size and degree of perilesional edema and/or rim enhancement, which can make diagnosis challenging.To study the clinical and radiological features, follow-up and final diagnosis of patients ...
Ayberk Selek +5 more
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Tumefactive Demyelination Appearing as Multiple Cystic Brain Lesions
World Neurosurgery, 2021Tumefactive demyelinating lesions (TDLs) are a rare sequelae of idiopathic inflammatory demyelinating diseases of the central nervous system. Their propensity to mimic tumor and abscess poses a diagnostic challenge for the clinician. Our case depicts TDLs causing right-hand focal sensory seizures in an otherwise healthy 35-year-old female.
David Wynne +2 more
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Prognostic factors in Tumefactive demyelinating lesions: A retrospective study
Journal of the Neurological Sciences, 2021Demyelinating lesions occasionally present as mass-like lesions on imaging, raising concern for malignancy. The disease course of such tumefactive demyelinating lesions (TDLs) is still being defined.We retrospectively analyzed 21 patients with new-onset neurologic symptoms and mass-like lesions on brain magnetic resonance imaging (MRI), which resulted ...
R Skipper, Plowman, Hemant, Varma
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Solitary Tumefactive Demyelinating Lesions in Children
Journal of Child Neurology, 2011Solitary tumefactive demyelination is rare in children, and the diagnosis is often conferred after brain biopsy. The authors report 3 children with solitary tumefactive demyelination and provide clinical and paraclinical clues to aid the clinician in reaching a diagnosis using a noninvasive approach.
Marie-Paule, Morin +4 more
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[Tumefactive demyelinating lesion (TDL)].
No shinkei geka. Neurological surgery, 2021Tumefactive demyelinating lesion(TDL)is defined as a large lesion, size >2 cm, mass effect, perilesional edema and/or ring enhancement. TDL could occur in multiple sclerosis(MS), neuromyelitis optica spectrum disorder(NMOSD), acute disseminated encephalomyelitis(ADEM)or other immunological diseases.
Akihiro, Nakajima, Izumi, Kawachi
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Characterisation of tumefactive demyelinating lesions
Journal of Neurology, Neurosurgery & Psychiatry, 2017Objectives Tumefactive demyelinating lesions (TDLs) occur spontaneously during the course of MS or as the first manifestation of demyelination and may be precipitated by drug withdrawal, vaccination, viral infection or fingolimod. The objective of this study was to identify the frequency, clinical context and radiological features of TDLs in a ...
Ariadna A Fontes-Villalba +2 more
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Tumefactive demyelinating lesion: perfusion-weighted imaging findings
European Journal of Radiology Extra, 2005Abstract There are so many reports in the literature about MRI findings of multiple sclerosis. Multiple sclerosis usually presents with disseminated plaques of demyelination. But in some cases, it presents with a large, solitary lesion with extensive edema and mass effect that mimic intracranial neoplasms.
PARLAK, MÜFİT +4 more
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