Results 51 to 60 of about 1,047 (134)

Progression of tumefactive demyelinating lesion in a child demonstrated with MRI

Radiology Case Reports, 2018
Tumefactive demyelinating lesions (TDLs) are atypical presentations of various demyelinating diseases. They can mimic brain tumors in their clinical and radiological features and usually respond favorably to corticosteroid therapy.
Marta De Simone, MD, Barbara Brogna, MD, Daniele Litterio Spitaleri, MD, Giulio Cicarelli, MD, Roberta Fantozzi, MD, Bruno Guida, MD   +5 more
doaj   +1 more source

Evaluating brain damage in multiple sclerosis with simultaneous multi‐angular‐relaxometry of tissue

Annals of Clinical and Translational Neurology, 2022
Objective Multiple sclerosis (MS) is a common demyelinating central nervous system disease. MRI methods that can quantify myelin loss are needed for trials of putative remyelinating agents.
Biao Xiang, Jie Wen, Robert E. Schmidt, Alexander L. Sukstanskii, Daniel Mamah, Dmitriy A. Yablonskiy, Anne H. Cross   +6 more
doaj   +1 more source

Pitfalls in the diagnosis of a tumefactive demyelinating lesion: A case report

Journal of Medical Case Reports, 2011
Introduction In rare instances, demyelinating disorders manifest as tumefactive lesions that simulate brain tumors. We report a patient with a space-occupying lesion in the parietal lobe, which presented a serious diagnostic dilemma, between a rare ...
Sakas Damianos, C Stavrinou Lampis, Boviatsis Efstathios, Gavra Maria   +3 more
doaj   +1 more source

Neuromyelitis Optica Mimicking Multiple Sclerosis: A Case Report and a Comprehensive Review of the Literature

Clinical Case Reports, Volume 13, Issue 10, October 2025.
Post‐gadolinium enhancement of the spinal cord seen in NMO. ABSTRACT Neuromyelitis optica spectrum disorder (NMOSD) may mimic other neurological conditions, including multiple sclerosis (MS). We report a 25‐year‐old woman with hypothyroidism and depression who presented with progressive quadriparesis.
Sunil Thatal, Susmin Karki, Asmita Parajuli, Sweta Bhandari, Bibek K. C., Dibasha Adhikari, Navin Kumar Sah   +6 more
wiley   +1 more source

Tumefactive multiple sclerosis requiring emergent biopsy and histological investigation to confirm the diagnosis: a case report

Journal of Medical Case Reports, 2012
Introduction Tumefactive multiple sclerosis is a demyelinating disease that demonstrates tumor-like features on magnetic resonance imaging. Although diagnostic challenges without biopsy have been tried by employing radiological studies and cerebrospinal ...
Yamada So, Yamada Shoko, Nakaguchi Hiroshi, Murakami Mineko, Hoya Katsumi, Matsuno Akira, Yamazaki Kazuto, Ishida Yasuo   +7 more
doaj   +1 more source

Stroke Mimicry: Unmasking a Brainstem Tuberculoma in a Young Patient

Clinical Case Reports, Volume 13, Issue 9, September 2025.
A young male presented with stroke‐like symptoms ‐ progressive hemiparesis and cranial nerve palsies. MRI brain revealed a ring‐enhancing intrapontine lesion with perilesional edema, suggestive of tuberculoma. Early initiation of anti‐tubercular therapy led to complete recovery.
Nithish Nanda Palanisamy, Dhiran Sivasubramanian, Virushnee Senthilkumar, Smrti Aravind, Sathwik Sanil, Karthick Balasubramanian   +5 more
wiley   +1 more source

The value of convolutional neural networks-based deep learning model in differential diagnosis of space-occupying brain diseases

Frontiers in Neurology, 2023
ObjectivesIt is still a challenge to differentiate space-occupying brain lesions such as tumefactive demyelinating lesions (TDLs), tumefactive primary angiitis of the central nervous system (TPACNS), primary central nervous system lymphoma (PCNSL), and ...
Xiuling Miao, Xiuling Miao, Tianyu Shao, Yaming Wang, Qingjun Wang, Jing Han, Xinnan Li, Yuxin Li, Chenjing Sun, Junhai Wen, Jianguo Liu, Jianguo Liu   +11 more
doaj   +1 more source

Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study

Annals of Clinical and Translational Neurology, Volume 12, Issue 8, Page 1566-1574, August 2025.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan, María A. Piedrabuena, María A. Zarate, Sofía Rodríguez Murúa, Ezequiel I. Surace, Mauricio F. Farez, Marcela P. Fiol, María C. Ysrraelit, Jorge Correale   +8 more
wiley   +1 more source

7 Tesla MRI in Multiple Sclerosis: Insights From Its Use in Clinical Routine

European Journal of Neurology, Volume 32, Issue 8, August 2025.
Insights from the impact of 7T MRI in routine clinical care in patients with not yet clearly defined neuro‐inflammatory disorders of the central nervous system or in MS patients with uncertainties during routine clinical care. ABSTRACT Background 7 Tesla (7 T) magnetic resonance imaging (MRI) offers higher spatial resolution and signal‐to‐noise ratio ...
A. León Betancourt, F. Messmer, A. Chan, R. Wiest, G. Bonanno, M. Capiglioni, R. Hoepner, F. Wagner, H. Hammer, P. Radojewski   +9 more
wiley   +1 more source

Magnetic resonance imaging in five patients with a tumefactive demyelinating lesion in the central nervous system [PDF]

Arquivos de Neuro-Psiquiatria, 1999
Five patients with a tumefactive lesion were clinically followed from 1992 to 1993. Four patients were female; age ranged from 32 to 57 years, the duration of symptoms varied from 3 days to 3 years.
HELGA C. ALMEIDA SILVA, DAGOBERTO CALLEGARO, PAULO E. MARCHIORI, MILBERTO SCAFF, ANA MARIA C. TSANACLIS   +4 more
doaj   +1 more source