Results 61 to 70 of about 1,047 (134)

Multifaceted Biomarkers Suggest a Similar Profile of CNS Pathology in Relapsing and Progressive MS

European Journal of Neurology, Volume 32, Issue 2, February 2025.
ABSTRACT Background Relapsing–remitting (RR) and primary progressive (PP) multiple sclerosis (MS) have distinct clinical courses, but underlying pathophysiological differences remain unclear. We compared pathological components between RRMS, PPMS, and other inflammatory and neurodegenerative disorders, leveraging soluble biomarkers and post‐mortem ...
Katelijn M. Blok, Romy A. M. Klein Kranenbarg, Kirtana Ananth, Hendrik J. Engelenburg, Aletta van den Bosch, Lucia A. A. Giannini, Janet de Beukelaar, Harro Seelaar, Inge Huitinga, Ari Green, Beatrijs Wokke, Ahmed Abdelhak, Joost Smolders   +12 more
wiley   +1 more source

Tumor-like Lesions in Primary Angiitis of the Central Nervous System: The Role of Magnetic Resonance Imaging in Differential Diagnosis

Diagnostics
Primary Angiitis of the Central Nervous System (PACNS) is a rare disease and its diagnosis is a challenge for several reasons, including the lack of specificity of the main findings highlighted in the current diagnostic criteria.
Marialuisa Zedde, Manuela Napoli, Claudio Moratti, Claudio Pavone, Lara Bonacini, Giovanna Di Cecco, Serena D’Aniello, Ilaria Grisendi, Federica Assenza, Grégoire Boulouis, Thanh N. Nguyen, Franco Valzania, Rosario Pascarella   +12 more
doaj   +1 more source

The Neuroimaging Spectrum of Neurosarcoidosis

Clinical Neuroimaging, Volume 2, Issue 1, 2025.
ABSTRACT Among its many forms, involvement of the nervous system in sarcoidosis ranks as one of the most severe and potentially disabling manifestations of the disease, and timely recognition and accurate diagnosis are critical for its optimal treatment.
Spencer K. Hutto, Gabriela A. Bou
wiley   +1 more source

Tumefactive Brain Lesions in Patients with Neuromyelitis Optica Spectrum Disorder

Caspian Journal of Neurological Sciences, 2019
Background: Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune neurological disorder that is characterized by optic neuritis and longitudinally-extended transverse myelitis lesions in spinal segments.
Navid Manouchehri, Nasim Nehzat, Omid Mirmosayeb, Vahid Shaygannejad, Mahdi Barzegar   +4 more
doaj  

Grey Matter Atrophy and its Relationship with White Matter Lesions in Patients with Myelin Oligodendrocyte Glycoprotein Antibody‐associated Disease, Aquaporin‐4 Antibody‐Positive Neuromyelitis Optica Spectrum Disorder, and Multiple Sclerosis

Annals of Neurology, Volume 96, Issue 2, Page 276-288, August 2024.
Objective To evaluate: (1) the distribution of gray matter (GM) atrophy in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), aquaporin‐4 antibody‐positive neuromyelitis optica spectrum disorder (AQP4+NMOSD), and relapsing–remitting multiple sclerosis (RRMS); and (2) the relationship between GM volumes and white matter lesions in ...
Rosa Cortese, Marco Battaglini, Ferran Prados, Giordano Gentile, Ludovico Luchetti, Alessia Bianchi, Lukas Haider, Anu Jacob, Jacqueline Palace, Silvia Messina, Friedemann Paul, Romain Marignier, Françoise Durand‐Dubief, Carolina de Medeiros Rimkus, Samira Luisa Apostolos Pereira, Douglas Kazutoshi Sato, Massimo Filippi, Maria Assunta Rocca, Laura Cacciaguerra, Àlex Rovira, Jaume Sastre‐Garriga, Georgina Arrambide, Yaou Liu, Yunyun Duan, Claudio Gasperini, Carla Tortorella, Serena Ruggieri, Maria Pia Amato, Monica Ulivelli, Sergiu Groppa, Matthias Grothe, Sara Llufriu, Maria Sepulveda, Carsten Lukas, Barbara Bellenberg, Ruth Schneider, Piotr Sowa, Elisabeth G. Celius, Anne‐Katrin Pröbstel, Cristina Granziera, Özgür Yaldizli, Jannis Müller, Bruno Stankoff, Benedetta Bodini, Frederik Barkhof, Olga Ciccarelli, Nicola De Stefano, for the MAGNIMS Study Group, F. Barkhof, N. de Stefano, J. Sastre‐Garriga, O. Ciccarelli, C. Enzinger, M. Filippi, Claudio Gasperini, L. Kappos, J. Palace, H. Vrenken, À. Rovira, M.A. Rocca, T. Yousry   +60 more
wiley   +1 more source

Fulminant demyelinating disease of the central nervous system effectively treated with a combination of decompressive craniectomy and immunotherapy: A case report and literature review

Clinical Case Reports, Volume 12, Issue 7, July 2024.
Key Clinical Message Accurately identifying fulminant demyelinating diseases is important for sudden onset of asymmetric cerebral white matter lesions with mass effect. Initially, immunotherapy should be administered; however, surgical intervention should be performed with poor response to medical management and evident signs of cerebral herniation ...
Toshihiro Ide, Ryo Ebashi, Makoto Eriguchi, Shinichi Aishima, Tatsuya Abe, Hideo Hara   +5 more
wiley   +1 more source

Sphingosine 1‐phosphate receptor modulators in multiple sclerosis treatment: A practical review

Annals of Clinical and Translational Neurology, Volume 11, Issue 4, Page 842-855, April 2024.
Abstract Four sphingosine 1‐phosphate (S1P) receptor modulators (fingolimod, ozanimod, ponesimod, and siponimod) are approved by the US Food and Drug Administration for the treatment of multiple sclerosis. This review summarizes efficacy and safety data on these S1P receptor modulators, with an emphasis on similarities and differences.
Patricia K. Coyle, Mark S. Freedman, Bruce A. Cohen, Bruce A. C. Cree, Clyde E. Markowitz   +4 more
wiley   +1 more source

Myelin oligodendrocyte glycoprotein antibody‐associated disorders: An overview

Clinical and Experimental Neuroimmunology, Volume 15, Issue 1, Page 6-15, February 2024.
Abstract In recent years, there is growing evidence of associations between antibodies against myelin oligodendrocyte glycoprotein (MOG) and several phenotypes of acute inflammatory demyelinating diseases such as acute disseminated encephalomyelitis (ADEM), optic neuritis, brainstem, and cerebral cortical encephalitis, called MOG antibody associated ...
Tatsuro Misu, Yuki Matsumoto, Kimihiko Kaneko, Toshiyuki Takahashi, Yoshiki Takai, Hirohiko Ono, Chihiro Namatame, Shuhei Nishiyama, Juichi Fujimori, Hiroshi Kuroda, Ichiro Nakashima, Kazuo Fujihara, Masashi Aoki   +12 more
wiley   +1 more source

Neuronavigation-guided biopsy for differential diagnosis of pseudotumoral demyelinating brain lesions

Interdisciplinary Neurosurgery, 2014
Marburg's disease (MD) is an extremely rare and aggressive form of multiple sclerosis (MS). In some cases, MD presents with tumefactive demyelinating lesions with a “tumor-like” appearance in MRI images, for which it may be difficult to achieve a form of
Antonella Giugno, MD, Giuseppe Salemi, MD, Cesare Gagliardo, MD, Ada Maria Florena, MD, Domenico Gerardo Iacopino, MD   +4 more
doaj   +1 more source

Tumefactive Demyelinating Lesions [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2007
Mark Hudon, Richard Farb, A. P. Mitha, J. N. Scott, D. George, A. Hanson, M. E. MacRae, R. B. Bell   +7 more
openaire   +2 more sources