Results 41 to 50 of about 1,258 (160)

Demyelinating Pseudotumours Presenting as Space Occupying Lesions Mimicking Brain Tumours- A Histopathologic Assessment of Seven Cases [PDF]

Journal of Clinical and Diagnostic Research, 2020
Demyelinating lesions which present as solitary contrast-enhancing masses pose a diagnostic challenge for both radiologists and surgical neuropathologists and can mimic a number of intracranial space occupying lesions either neoplastic/inflammatory ...
B DEEPTHI, SOMASEKHAR POTHULA
doaj   +1 more source

Case report: A novel case of COVID-19 triggered tumefactive demyelinating lesions in one multiple sclerosis patient

Frontiers in Neuroscience, 2023
The epidemic of COVID-19 is mainly manifested by respiratory symptoms caused by SARS-CoV-2 infection. Recently, reports of central nervous system diseases caused or aggravated by SARS-CoV-2 infection are also increasing. Thus, the COVID-19 pandemic poses
Jinghan Hu, Leiyun Huang, Zengyun Qiu, Yongzhen Liu, Kaiming Shen, Bin Tang, Jing Qian, Jing Qian   +7 more
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Coexistence of Multiple Sclerosis and Brain Tumor: An Uncommon Diagnostic Challenge

Advanced Biomedical Research, 2017
Nonneoplastic demyelinating processes of the brain with mass effect on magnetic resonance imaging can cause diagnostic difficulties. It requires differential diagnosis between the tumefactive demyelinating lesion and the coexistence of neoplasm.
Fatemeh Abrishamchi, Fariborz Khorvash
doaj   +1 more source

The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study

Annals of Clinical and Translational Neurology, Volume 12, Issue 12, Page 2535-2545, December 2025.
ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey, Ahmad A. Toubasi, Jiacheng Wang, Habeeb F. Kazimuddin, Taegan Vinarsky, Caroline Gheen, Carynn Koch, Zachery Rohm, Bryan Hernandez, Margareta A. Clarke, Rachael Cheek, Rozita Khalili, Chaoyang Jin, Victoria Lim, John Kramer, Junzhong Xu, Ipek Oguz, Francesca Bagnato   +17 more
wiley   +1 more source

Magnetic resonance imaging in five patients with a tumefactive demyelinating lesion in the central nervous system [PDF]

Arquivos de Neuro-Psiquiatria, 1999
Five patients with a tumefactive lesion were clinically followed from 1992 to 1993. Four patients were female; age ranged from 32 to 57 years, the duration of symptoms varied from 3 days to 3 years.
HELGA C. ALMEIDA SILVA, DAGOBERTO CALLEGARO, PAULO E. MARCHIORI, MILBERTO SCAFF, ANA MARIA C. TSANACLIS   +4 more
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Molecular imaging of multiple sclerosis: from the clinical demand to novel radiotracers

EJNMMI Radiopharmacy and Chemistry, 2019
Background Brain PET imaging with different tracers is mainly clinically used in the field of neurodegenerative diseases and brain tumors. In recent years, the potential usefulness of PET has also gained attention in the field of MS.
Matteo Bauckneht, Selene Capitanio, Stefano Raffa, Luca Roccatagliata, Matteo Pardini, Caterina Lapucci, Cecilia Marini, Gianmario Sambuceti, Matilde Inglese, Paolo Gallo, Diego Cecchin, Flavio Nobili, Silvia Morbelli   +12 more
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Neuromyelitis Optica Mimicking Multiple Sclerosis: A Case Report and a Comprehensive Review of the Literature

Clinical Case Reports, Volume 13, Issue 10, October 2025.
Post‐gadolinium enhancement of the spinal cord seen in NMO. ABSTRACT Neuromyelitis optica spectrum disorder (NMOSD) may mimic other neurological conditions, including multiple sclerosis (MS). We report a 25‐year‐old woman with hypothyroidism and depression who presented with progressive quadriparesis.
Sunil Thatal, Susmin Karki, Asmita Parajuli, Sweta Bhandari, Bibek K. C., Dibasha Adhikari, Navin Kumar Sah   +6 more
wiley   +1 more source

IgG4‐Related Disease: Emerging Roles of Novel Genetic Variants, Immune Cell Subsets and Therapeutic Targets

Allergy, Volume 80, Issue 10, Page 2738-2754, October 2025.
ABSTRACT IgG4, the least abundant IgG subclass in humans, is increasingly recognised for its involvement in allergic and autoimmune pathologies. Its unique properties, such as the tendency to form half‐molecules (one heavy chain and one light chain) and its generally non‐inflammatory nature, distinguish it from other IgG subclasses.
Louisa Tedesco, Syed B. Ali, Baran Erman, Safa Baris, Harshita Pant, Pravin Hissaria, Yelda Bilginer, Damon J. Tumes, Gökhan Cildir   +8 more
wiley   +1 more source

Stroke Mimicry: Unmasking a Brainstem Tuberculoma in a Young Patient

Clinical Case Reports, Volume 13, Issue 9, September 2025.
A young male presented with stroke‐like symptoms ‐ progressive hemiparesis and cranial nerve palsies. MRI brain revealed a ring‐enhancing intrapontine lesion with perilesional edema, suggestive of tuberculoma. Early initiation of anti‐tubercular therapy led to complete recovery.
Nithish Nanda Palanisamy, Dhiran Sivasubramanian, Virushnee Senthilkumar, Smrti Aravind, Sathwik Sanil, Karthick Balasubramanian   +5 more
wiley   +1 more source

Recurrent Fulminant Tumefactive Demyelination With Marburg-Like Features and Atypical Presentation: Therapeutic Dilemmas and Review of Literature

Frontiers in Neurology, 2020
Atypical forms of demyelinating diseases with tumor-like lesions and aggressive course represent a diagnostic and therapeutic challenge for neurologists.
Aigli G. Vakrakou, Dimitrios Tzanetakos, Theodore Argyrakos, Georgios Koutsis, Maria-Eleptheria Evangelopoulos, Elisabeth Andreadou, Maria Anagnostouli, Marianthi Breza, John S. Tzartos, Elias Gialafos, Antonios N. Dimitrakopoulos, Georgios Velonakis, Panagiotis Toulas, Leonidas Stefanis, Constantinos Kilidireas   +14 more
doaj   +1 more source