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Automatic Brain Tumor Segmentation using Cascaded Anisotropic Convolutional Neural Networks [PDF]

open access: yes, 2017
A cascade of fully convolutional neural networks is proposed to segment multi-modal Magnetic Resonance (MR) images with brain tumor into background and three hierarchical regions: whole tumor, tumor core and enhancing tumor core.
Li, Wenqi   +3 more
core   +2 more sources

The Role of ARID1A in Tumors: Tumor Initiation or Tumor Suppression? [PDF]

open access: yesFrontiers in Oncology, 2021
Genes encoding subunits of SWItch/Sucrose Non-Fermenting (SWI/SNF) chromatin remodeling complexes are collectively mutated in 20% of all human cancers, among which the AT-rich interacting domain−containing protein 1A (ARID1A, also known as BAF250a, B120, C1orf4, Osa1) that encodes protein ARID1A is the most frequently mutated, and mutations in ARID1A ...
Shouying Xu, Chao Tang
openaire   +4 more sources

Effect of Radical Surgery for Advanced Adenocarcinoma of Esophagogastric Junction on Perioperative Cellular Cell Immunity

open access: yesJournal of Investigative Surgery, 2021
Background: To investigate the perioperative peripheral blood levels of CD4+CD25+ regulatory T cells, programed cell death 1 (PD-1), and lymphocyte activation gene 3 (LAG-3) in patients with advanced Siewert type II adenocarcinoma of esophagogastric ...
Shou-miao Li   +5 more
doaj   +1 more source

Tumor Hypoxia and Circulating Tumor Cells [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Circulating tumor cells (CTCs) are a rare tumor cell subpopulation induced and selected by the tumor microenvironment’s extreme conditions. Under hypoxia and starvation, these aggressive and invasive cells are able to invade the lymphatic and circulatory systems.
Tinganelli W., Durante M.
openaire   +5 more sources

Impairing flow-mediated endothelial remodeling reduces extravasation of tumor cells

open access: yesScientific Reports, 2021
Tumor progression and metastatic dissemination are driven by cell-intrinsic and biomechanical cues that favor the growth of life-threatening secondary tumors.
Gautier Follain   +13 more
doaj   +1 more source

Low expression of PRDM5 predicts poor prognosis of esophageal squamous cell carcinoma

open access: yesBMC Cancer, 2022
Background The role of the PRDM5 in esophageal squamous cell carcinoma (ESCC) has not been revealed. This study investigated the relationship between PRDM5 expression and survival outcome in esophageal squamous cell carcinoma and explored the mechanism ...
Jing Guo   +8 more
doaj   +1 more source

Ultrasound-Triggered on Demand Lidocaine Release Relieves Postoperative Pain

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Safe and non-invasive on-demand relief is a crucial and effective treatment for postoperative pain because it considers variable timing and intensity of anesthetics.
Xiaohong Chen   +8 more
doaj   +1 more source

Research on radiotherapy related genes and prognostic target identification of rectal cancer based on multi-omics

open access: yesJournal of Translational Medicine, 2023
Background Radiosensitivity of rectal cancer is related to the radiotherapy efficacy and prognosis of patients with rectal cancer, and the genes and molecular mechanisms related to radiosensitivity of rectal cancer have not been clarified.
Yi Liu   +6 more
doaj   +1 more source

Effect of bladder filling status on positioning errors in post-hysterectomy cervical cancer radiotherapy

open access: yesAnnals of Medicine, 2023
Objective: To investigate the effect of different bladder filling states on positioning errors in radiotherapy for cervical cancer and obtain the reference range of bladder filling consistency during radiotherapy.Methods: Patients who underwent ...
Bin-Bin Ge   +10 more
doaj   +1 more source

circ_0052184 Promotes Colorectal Cancer Progression via Targeting miR-604/HOXA9 Axis

open access: yesAnalytical Cellular Pathology, 2022
Background. The mortality rate of colorectal cancer (CRC) ranks second. circRNAs are abnormal expression in some diseases, and their dysregulation is associated with cancer progression.
Yandong Huang   +8 more
doaj   +1 more source

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