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Tumor organoid and tumor-on-a-chip equipped next generation precision medicine
BiofabricationAbstract Recently, significant advancements have been witnessed in various in vitro treatment evaluation models, especially organoids and organs-on-chips. In vitro culture of cancer cells and drug screening are key technical components in functional oncology precision medicine. However, most studies primarily focus on constructing models
Wentao Zhao +8 more
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Tumor-on-a-chip devices for cancer immunotherapy
2022Xuan Mu, Yu Shrike Zhang
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Immunocompetent tumor-on-a-chip: A translational tool for drug screening and cancer therapy
Critical Reviews in Oncology/HematologyTumor is one of the major diseases endangering human health while establishing an efficient in vitro tumor microenvironment (TME) model, which is an effective way to reveal the nature of the tumor and develop therapeutic methods. In recent years, due to the continuous development of lab-on-a-chip technology and tumor biology, various tumor-on-a-chip ...
Anqi Liang +6 more
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The Investigation of Tumor-on-a-Chip via 3D-Bioprinting Methods
2021Die zweithäufigste Todesursache weltweit, nach Herz-Kreislauf-Erkrankungen, ist Krebs mit ständig steigender Prävalenz. Cholangiokarzinom ist ein vielfältiger, seltener und aggressiver epithelialer Tumor mit weltweit zunehmender Inzidenz und schlechter Prognose. Daher wird viel Augenmerk auf die Suche nach einem geeigneten Arzneimittel-Screening-Modell
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Tumor-on-a chip in 3D microfluidic device for immunotherapy study
Extended Abstracts of the 2022 International Conference on Solid State Devices and Materials, 2022Yu-Chen - Chen +6 more
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Advanced Therapeutics
AbstractVascularized tumor on a chip (VToC) entail emulating intricate microvascular networks like those observed in tumors through microfluidic devices, which are meticulously designed to offer a faithful representation of cancer in vitro, exploration of tumor biology, evaluation of drug efficacy, and anticipation of patient responses to therapies ...
Pratibha Parihar +5 more
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AbstractVascularized tumor on a chip (VToC) entail emulating intricate microvascular networks like those observed in tumors through microfluidic devices, which are meticulously designed to offer a faithful representation of cancer in vitro, exploration of tumor biology, evaluation of drug efficacy, and anticipation of patient responses to therapies ...
Pratibha Parihar +5 more
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A tumor-on-a-chip for in vitro study of CAR-T cell immunotherapy in solid tumors
Nature BiotechnologyOur limited understanding of cancer-immune interactions remains a critical barrier to advancing chimeric antigen receptor (CAR)-T cell therapy for solid malignancies. Here, we present a microengineered system that enables vascularization of human tumor explants and their controlled perfusion with immune cells to model the activity of CAR-T cells in the
Haijiao Liu +31 more
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Brain and other central nervous system tumor statistics, 2021
Ca-A Cancer Journal for Clinicians, 2021Jill Barnholtz-Sloan, Carol Kruchko
exaly
Technological Advances in Tumor-On-Chip Technology: From Bench to Bedside
Cancers, 2021Valerie Taly
exaly
Tumor-on-a-chip: new strategies of in-vitro cancer cell culture
2022Aquest projecte proposa un marc per crear dispositius microfluídics per al cultiu cel·lular, inspirats en organ-on-a-chip i tumor-on-a-chip i fabricats en gran part amb la fabricació de filaments fusionats. Aquesta tecnologia única promet simplificar i minimitzar els costos de fabricació, facilitar l'adaptació dels xips de cultiu a l'aplicació actual ...
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