Results 281 to 290 of about 91,694,512 (315)

Wireless, Deep‐Seeing Smart Pill: A NIR‐II Fluorescence Imaging Capsule Endoscope for Gastrointestinal Cancer

Advanced Science, EarlyView.
A novel near‐infrared‐II fluorescent imaging capsule endoscope that detects specific fluorescence signals above 900 nm enables highly sensitive, targeted imaging of gastrointestinal cancer tissue. This wirelessly powered and magnetically controlled “smart pill” achieves high sensitivity and deep tissue penetration, allowing precise, non‐invasive ...
Weicheng Wang, Jinlei Jiang, Zhengting Wang, Shuqi Liu, Wei Wang, Xi Chen, Qirui Zhao, Xinyuan Cui, Cheng Zhou, Shengsheng Cui, Daxiang Cui   +10 more
wiley   +1 more source

Construction of Multicellular Tumor-On-A-Chip Models for Ovarian Cancer Research

Engineering
Jiexian Ye, Hao Lin, Zilin Zhang, Shihui Xu, Feili Yang, Xuemei Zhuansun, Feng Ji, Yusha Zhang, Yuxin Zhu, Jing Zhang, Zaozao Chen, Zhongze Gu, Yang Shen   +12 more
openaire   +1 more source

Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning

Advanced Science, EarlyView.
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen, Jiahui Xie, Yi Liao, Junyu Li, Longqi Liu, Xin Gao, Hongmin Cai   +6 more
wiley   +1 more source

A microfluidic tumor-on-chip platform deciphers hypoxia-driven FOXO3a/PD-L1 signaling in gastric cancer immunotherapy resistance

Hanting Xiang, Fangqian Chen, Zhebin Dong, Xianlei Cai, Yuan Xu, Zhengwei Chen, Sangsang Chen, Tianci Chen, Jiarong Huang, Fangfang Chen, Yahua Zheng, Jingyun Ma, Weiming Yu, Chao Liang   +13 more
openalex   +1 more source

Spatiotemporal dissection of tumor microenvironment via in situ sensing and monitoring in tumor-on-a-chip [PDF]

Biosensors and Bioelectronics, 2023
Lang Zhou, Lunan Liu, Weiqiang Chen
exaly   +2 more sources

3D Biomimetic Models to Reconstitute Tumor Microenvironment In Vitro: Spheroids, Organoids, and Tumor‐on‐a‐Chip [PDF]

Advanced Healthcare Materials, 2023
Xiaoyu Zhou, Bee Luan Khoo, Changqing Yi   +2 more
exaly   +2 more sources

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Advances in 3D Vascularized Tumor-on-a-Chip Technology

2022
Tumors disrupt the normal homeostasis of human body as they proliferate in abnormal speed. For constant proliferation, tumors recruit new blood vessels transporting nutrients and oxygen. Immune system simultaneously recruits lymphatic vessels to induce the death of tumor cells. Hence, understanding tumor dynamics are important to developing anti-cancer
Sangmin, Jung, Hyeonsu, Jo, Sujin, Hyung, Noo Li, Jeon   +3 more
openaire   +2 more sources

The design basis and application in urology of the tumor-on-a-chip platform

Urologic Oncology: Seminars and Original Investigations, 2022
Clinical research has been desperately looking for effective treatments for tumors. As the molecular mechanisms of tumors have not been thoroughly defined, and the problem of anti-tumor drug resistance and clinical drug screening are not effective, new ways are currently needed to explore and improve.
Fei Sheng, Rui-peng Jia
openaire   +2 more sources

Tumor‐On‐A‐Chip Models for Predicting In Vivo Nanoparticle Behavior

Small
AbstractNanosized drug formulations are broadly explored for the improvement of cancer therapy. Prediction of in vivo nanoparticle (NP) behavior, however, is challenging, given the complexity of the tumor and its microenvironment. Microfluidic tumor‐on‐a‐chip models are gaining popularity for the in vitro testing of nanoparticle targeting under ...
Roland Brock, Wouter P R Verdurmen, Kim E De Roode   +2 more
exaly   +5 more sources

Ex Vivo Evaluation of Combination Immunotherapy Using Tumor‐Microenvironment‐on‐Chip

Advanced Healthcare Materials, 2023
AbstractCombination immunotherapy has emerged as a promising strategy to address the challenges associated with immune checkpoint inhibitor (ICI) therapy in breast cancer. The efficacy of combination immunotherapy hinges upon the intricate and dynamic nature of the tumor microenvironment (TME), characterized by cellular heterogeneity and molecular ...
Hsuan‐Yu Mu, Chiao‐Min Lin, Li‐An Chu, Ya‐Hui Lin, Ji Li, Chao‐Yu Liu, Hsi‐Chien Huang, Sheng‐Liang Cheng, Tsung‐Ying Lee, Hsin Mei Lee, Hsin‐Min Chen, Yun‐Jen Tsai, Yunching Chen, Jen‐Huang Huang   +13 more
openaire   +2 more sources