Journal of Orthopaedics and Traumatology, 2022 Background Improved patient and limb survival rates have led to an increased interest in the functional outcome and return to sports of patients undergoing megaprosthetic reconstruction in musculoskeletal oncology.
Moritz Ellerbrock +6 more
doaj +1 more source
Comprehensive analysis of normal adjacent to tumor transcriptomes. [PDF]
, 2017 Histologically normal tissue adjacent to the tumor (NAT) is commonly used as a control in cancer studies. However, little is known about the transcriptomic profile of NAT, how it is influenced by the tumor, and how the profile compares with non-tumor ...
Aran, Dvir +8 more
core +3 more sources
The Tumor Microenvironment Innately Modulates Cancer Progression.
Cancer Research, 2019 Cancer development and progression occurs in concert with alterations in the surrounding stroma. Cancer cells can functionally sculpt their microenvironment through the secretion of various cytokines, chemokines, and other factors.
D. Hinshaw, L. Shevde
semanticscholar +1 more source
Research Advances in Antitumor Mechanism of Evodiamine
Journal of Chemistry, 2022 Evodiamine is a natural alkaloid extracted from Fructus Evodia. This bioactive alkaloid has been reported to have a wide range of biological activities, including anti-injury, antiobesity, vasodilator, and anti-inflammatory effects.
Luning Li +5 more
doaj +1 more source
Prognostic significance of primary-tumor extension, stage and grade of nuclear differentiation in patients with renal cell carcinoma [PDF]
, 2002 Surgery remains the preferred therapy for renal cell carcinoma. The various adjunctive or complementary therapies currently yield disappointing results. Identifying reliable prognostic factors could help in selecting patients most likely to benefit from ...
Barbarosos A +7 more
core
Pathologic evaluation of tumor-associated macrophage density and vessel inflammation in invasive breast carcinomas [PDF]
, 2017 Tumor-associated macrophages (TAMs) are major constituents of the tumor microenvironment in solid tumors and have been implicated as mediators of tumor progression, invasion and metastasis.
Adhikari, Smita +7 more
core +2 more sources
Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden
New England Journal of Medicine, 2018 BACKGROUND Nivolumab plus ipilimumab showed promising efficacy for the treatment of non–small‐cell lung cancer (NSCLC) in a phase 1 trial, and tumor mutational burden has emerged as a potential biomarker of benefit.
M. Hellmann +23 more
semanticscholar +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
Massage Stimulation Reduces Tumor Necrotic Factor-alpha and Interleukin-6 in Preterm, Low Birth Weight with Appropriate Gestational Age Newborns [PDF]
, 2013 Preterm newborn is susceptible from various stresses such as infections or non infections. During stress, immune response is activated by synthesizing and releasing of cytokines from activated immune cells into the circulation.
Astawa, N. M. (N) +3 more
core
Ubiquinol Reduces Muscle Wasting but Not Fatigue in Tumor-Bearing Mice [PDF]
, 2014 Purpose: Fatigue is the most common and distressing symptom reported by cancer patients during and after treatment. Tumor growth increases oxidative stress and cytokine production, which causes skeletal muscle wasting and cardiac dysfunction. The purpose
Clark, Yvonne +3 more
core +2 more sources