Results 211 to 220 of about 1,252,032 (285)

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

iMetaOmics, Volume 3, Issue 3, September 2026.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang, Shouwen Du, Yuchen Liu, Letian Li, Xi Wu, Yanzhi Yuan, Chaozhi Jin, Qingkun Mi, Yuhang Wang, Xiaoshuang Shi, Jiamin Wang, Guoqing Zhang, Yidan Ma, Weijin Huang, Jigang Wang, Jian Wang, Chang Li   +16 more
wiley   +1 more source

Tumor budding in preoperative breast biopsies predicts sentinel lymph node metastasis. [PDF]

Biomol Biomed
Ozer SP, Ozer B, Aktas G.
europepmc   +1 more source

Engineering Extracellular Vesicles: Strategies for Functional Modification and Clinical Translation

iNew Medicine, Volume 2, Issue 3, September 2026.
The engineering modification strategies of extracellular vesicles (EVs). This figure presents the four core technical systems for the engineering modification of EVs, including direct modification strategies (physical and chemical methods), biological engineering methods, and hybrid and bionic strategies.
Zhouming Cheng, Wenhui Zhao, Min Wang, Xianwen Wang   +3 more
wiley   +1 more source

Tumor budding predicts lymph node metastasis in squamous cell carcinoma of the lip. [PDF]

Head Face Med
Leypold S, Riese J, Cacchi C, Wermker K, Vladu O, Jonigk D, Hölzle F, Klein M.   +7 more
europepmc   +1 more source

Engineering Piezo1‐Mediated Calcium Signalling for Enhanced Extracellular Vesicle Biogenesis and Cargo Loading

Journal of Extracellular Biology, Volume 5, Issue 9, September 2026.
ABSTRACT Cell‐derived extracellular vesicles (EVs) are promising nanocarriers for therapeutic delivery platforms owing to their biocompatibility and capacity to protect and efficiently transport bioactive molecules. However, EV‐based therapeutics remain constrained by inefficient cargo loading and low production yields, which limit scalable ...
Najla A. Saleh, Rozita Shafiq, Amanda P. Cicerone, Sadhana Kilangodi, Hayden Hartwig, George I. Mias, Guangqing Lu, Jun R. Huh, Weiping Li, Cheri X. Deng, Masamitsu Kanada   +10 more
wiley   +1 more source

Poorly differentiated clusters surpass tumor budding as novel prognostic factors in pancreatic cancer, especially in cases treated with neoadjuvant chemotherapy. [PDF]

BMC Gastroenterol
Uchihara D, Shimajiri S, Harada Y, Kumamoto K, Oe S, Miyagawa K, Nakamura K, Katafuchi E, Nuratdinova F, Honma Y, Shibata M, Harada M, Nakayama T.   +12 more
europepmc   +1 more source

Noncoding RNA Transcripts Based Molecular Phenotyping of MASLD and MASH Patients

Liver International Communications, Volume 7, Issue 3, September 2026.
ABSTRACT Background and Aims Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a progressive hepatic metabolic disorder characterized by excessive fat accumulation in hepatocytes. MASLD can advance to metabolic dysfunction‐associated steatohepatitis (MASH).
Frida M. Delgadillo, Karla Perez, Barbara Yang, Subramanian Dhandayuthapani, Murali M. Yallapu, Subhash C. Chauhan, Enrique I. Ramos, Shrikanth S. Gadad   +7 more
wiley   +1 more source

Digital Pathology and the AI-Based Quantification of the Tumor Microenvironment in Gastrointestinal Cancer: From Tumor Budding and Tumor-Infiltrating Lymphocytes to Tertiary Lymphoid Structures. [PDF]

Int J Mol Sci
Łapińska J, Kasperczuk K, Kańczugowska K, Gałan A, Pająk W, Kleinrok J, Sitarz R, Baj J, Korolczuk A.   +8 more
europepmc   +1 more source

Advances in FGF/FGFR Signaling: Implications for Disease and Therapy

MedComm, Volume 7, Issue 9, September 2026.
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song, Xi Liu, Yang Xiao, Yongsheng Li, Huakan Zhao   +4 more
wiley   +1 more source

Applications of Mesenchymal Stromal Cells for Treatment of Diseases

MedComm, Volume 7, Issue 9, September 2026.
This schematic summarizes the major therapeutic mechanisms of MSCs across different disease systems and highlights factors associated with MSCs dysfunction, together with current strategies to enhance MSCs function and therapeutic efficacy. This summary diagram illustrates that MSCs exert therapeutic effects in various diseases through multiple ...
Dongmei Xue, Yongsheng Li, Lei Wu
wiley   +1 more source