Results 251 to 260 of about 1,252,032 (285)

Tumor budding in colorectal cancer—ready for diagnostic practice? [PDF]

Human Pathology, 2016
Tumor budding is an important additional prognostic factor for patients with colorectal cancer (CRC). Defined as the presence of single tumor cells or small clusters of up to 5 cells in the tumor stroma, tumor budding has been likened to an epithelial ...
Inti Zlobec, Viktor Koelzer, Alessandro Lugli   +2 more
exaly   +2 more sources

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Prognostic significance of tumor budding in melanoma

Melanoma Research, 2022
Cutaneous melanoma is an aggressive neoplasm with growing incidence and continuous research is undertaken for novel prognostic factors. This current research aims to determine if tumor budding is an independent factor that correlates with the survival of patients with melanoma. A total of 742 cases of melanoma were evaluated. A receiver operating curve
Leonardo S, Lino-Silva, César, Zepeda-Najar, Claudia H, Caro-Sánchez, Ángel, Herrera-Gómez, Rosa A, Salcedo-Hernández   +4 more
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Intratumoral budding as a potential parameter of tumor progression in mismatch repair–proficient and mismatch repair–deficient colorectal cancer patients

Human Pathology, 2011
In colorectal cancer, tumor budding at the invasive front (peritumoral budding) is an established prognostic parameter and decreased in mismatch repair-deficient tumors.
Inti Zlobec, George Peroš, Tatjana Vlajnić   +2 more
exaly   +2 more sources

Tumor Budding Assessment in Colorectal Carcinoma

American Journal of Surgical Pathology, 2023
Tumor budding (TB) is a powerful prognostic factor in colorectal cancer (CRC). An internationally standardized method for its assessment (International Tumor Budding Consensus Conference [ITBCC] method) has been adopted by most CRC pathology protocols. This method requires that TB counts are reported by field area (0.785 mm2) rather than objective lens
David P, Cyr, Cherry, Pun, Sameer, Shivji, Bojana, Mitrovic, Kai, Duan, Rossi, Tomin, Aysegul, Sari, Amanpreet, Brar, Siham, Zerhouni, Mantaj S, Brar, Erin D, Kennedy, Carol J, Swallow, Richard, Kirsch, James R, Conner   +13 more
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Prognostic significance of tumor budding in gastrointestinal tumors

Expert Review of Anticancer Therapy, 2011
Tumor budding describes the presence of single tumor cells or small tumor cell clusters at the invasion front of carcinomas. It is currently thought to be the result of epithelial-mesenchymal transformation. Tumor budding can be appreciated histologically during routine evaluation of malignant polyps or surgical specimens of malignant tumors.
Märkl, Bruno, Arnholdt, Hans M.
openaire   +2 more sources

Prognostic value of tumor budding in gallbladder cancer: application of the International Tumor Budding Consensus Conference scoring system

Virchows Archiv, 2021
Tumor budding (TB), a histopathological manifestation of epithelial-mesenchymal transition, is an important step in cancer invasion and metastasis development. TB has been considered a strong prognostic indicator in colorectal cancer. The International Tumor Budding Consensus Conference (ITBCC) scoring system is the standardized method used for patient
Han-Na Kim, Soo Yeon Lee, Baek-hui Kim, Chung-Yeul Kim, Aeree Kim, Hayeon Kim   +5 more
openaire   +2 more sources

Tumor Budding in Intrahepatic Cholangiocarcinoma

American Journal of Surgical Pathology, 2019
Intrahepatic cholangiocarcinoma (ICC) is an extremely aggressive carcinoma. Useful predictors for the patients’ prognosis after surgery have not been fully established. From the University of Tokyo Hospital pathology archives, we reviewed 107 cases of ICC, 54 cases of perihilar cholangiocarcinoma, and 40 cases of extrahepatic cholangiocarcinoma (ECC ...
Mariko, Tanaka, Naoko, Yamauchi, Tetsuo, Ushiku, Junji, Shibahara, Akimasa, Hayashi, Kento, Misumi, Yoichi, Yasunaga, Teppei, Morikawa, Takashi, Kokudo, Junichi, Arita, Yoshihiro, Sakamoto, Kiyoshi, Hasegawa, Masashi, Fukayama   +12 more
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Prognostic and Predictive Value of Tumor Budding in Colorectal Cancer

Clinical Colorectal Cancer, 2021
Tumor budding (TB) is an adverse prognostic factor in colorectal cancer (CRC). International consensus on a standardized assessment method has led to its wider reporting. However, uncertainty regarding its clinical value persists. This study aimed to (1) confirm the prognostic significance of TB, particularly in stage II CRC; (2) to determine optimum ...
Bojana Mitrovic, Kelly Handley, Naziheh Assarzadegan, Hector Li Chang, Heather A.E. Dawson, Andrea Grin, Gordon G.A. Hutchins, Laura Magill, Philip Quirke, Robert H. Riddell, Richard G Gray, Richard Kirsch   +11 more
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Quantifying Tumor Budding

American Journal of Surgical Pathology
The mechanism of tumor budding (TB) in gastric adenocarcinoma (GAC) and its relationship with biological indicators and prognostic significance, remains unclear. In this study, we conducted a comprehensive analysis using whole-slide imaging to evaluate TB in 75 cases of GAC.
Jie Lian, Wenwen Zhang, Chunbao Wang, Yun Zhang, Luyang Wang, Pengfei Nan, Xuqi Li   +6 more
openaire   +2 more sources

The phenomenon of tumor budding in gastric cancer

Russian Journal of Archive of Pathology
Gastric cancer remains the fifth most common malignant neoplasm in the world and ranks fifth among the causes associated with cancer. The TNM system remains the gold standard for predictive stratification of patients with gastric cancer, but the search for new sensitive, specific and reproducible biomarkers to develop a personalized approach to the ...
T.M. Polushkina, E.E. Porubaeva, N.V. Danilova   +2 more
openaire   +2 more sources