20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti+5 more
wiley +1 more source
Therapeutic potential of T-cell receptor targeting the HLA-A*11:01-restricted KRAS<sup>G12V</sup> neoantigen without cross-recognition of the self-antigen RAB7B in solid tumors. [PDF]
Shen M+12 more
europepmc +1 more source
FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang+5 more
wiley +1 more source
Transdifferentiation of tongue muscle cells into cancer-associated fibroblasts in response to tongue squamous cell carcinoma. [PDF]
Lin W+7 more
europepmc +1 more source
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
Free Methylglyoxal and Lactate Produced and Released by Cultured Cancer and Non-Cancer Cells: Implications for Tumor Growth and Development. [PDF]
Belpomme D+5 more
europepmc +1 more source
Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang+6 more
wiley +1 more source
Acetate promotes T cell effector function during glucose restriction [PDF]
Egawa, Takeshi+2 more
core +1 more source
Jaagsiekte sheep retrovirus infection of lung slice cultures [PDF]
A Abbott+66 more
core +1 more source
Sphingosine 1-phosphate derived from tumor-educated hepatic stellate cells combining with S1PR4 promotes tumor associated macrophages differentiation through FAO modulation. [PDF]
Feng R, Cui Z, Yang L, Liu Z.
europepmc +1 more source