Results 101 to 110 of about 14,776,627 (313)
Liquid Biopsy in Rare Cancers: Lessons from Hemangiopericytoma
Analytical Cellular Pathology, 2018 Hemangiopericytoma (HPT) is a rare mesenchymal tumor of fibroblastic type and for its rarity is poorly studied. The most common sites of metastatic disease in patients with intracranial HPT are the bone, liver, and lung, suggestive for an hematogenous ...
Chiara Nicolazzo +9 more
doaj +1 more source
Emergent Properties of Tumor Microenvironment in a Real-life Model of Multicell Tumor Spheroids [PDF]
, 2010 Multicellular tumor spheroids are an important {\it in vitro} model of the pre-vascular phase of solid tumors, for sizes well below the diagnostic limit: therefore a biophysical model of spheroids has the ability to shed light on the internal workings and organization of tumors at a critical phase of their development.
arxiv +1 more source
Full-Length mRNA-Seq from single cell levels of RNA and individual circulating tumor cells
Nature Biotechnology, 2012 Genome-wide transcriptome analyses are routinely used to monitor tissue-, disease- and cell type–specific gene expression, but it has been technically challenging to generate expression profiles from single cells.
D. Ramsköld +11 more
semanticscholar +1 more source
Frontiers in OncologyBackgroundThe heterogeneous and complex genetic landscape of NSCLC impacts the clinical outcomes of patients who will eventually develop resistance to osimertinib.
Aliki Ntzifa +5 more
doaj +1 more source
Emerging Allee effect in tumor growth [PDF]
arXiv, 2014 Tumor cells develop different features to adapt to environmental conditions. A prominent example is the ability of tumor cells to switch between migratory and proliferative phenotypes, a phenomenon known as go-or-grow mechanism. It is however unclear how this particular phenotypic plasticity affects overall tumor growth.
arxiv
Safety, tumor trafficking and immunogenicity of chimeric antigen receptor (CAR)-T cells specific for TAG-72 in colorectal cancer. [PDF]
, 2017 BackgroundT cells engineered to express chimeric antigen receptors (CARs) have established efficacy in the treatment of B-cell malignancies, but their relevance in solid tumors remains undefined.
A Molinolo +42 more
core +1 more source
Thymic Stromal Lymphopoietin and Cancer: Th2-Dependent and -Independent Mechanisms
Frontiers in Immunology, 2020 The thymic stromal lymphopoietin (TSLP) is an IL-7-like cytokine originally cloned from a murine thymic stromal cell line, and subsequently a human homolog was identified using database search methods.
Maria Pia Protti +3 more
doaj +1 more source
Tumor can originate from not only rare cancer stem cells [PDF]
arXiv, 2013 Tumors are believed to consist of a heterogeneous population of tumor cells originating from rare cancer stem cells (CSCs). However, emerging evidences show that tumor may also originate from non-CSCs. Here, we give evidences supporting that the number of tumorigenic tumor cells is higher than the number of CSCs and tumor can also derive from non-CSCs.
arxiv
Journal of Clinical Oncology, 2008 PURPOSE As treatment options expand for metastatic colorectal cancer (mCRC), a blood marker with a prognostic and predictive role could guide treatment.
Steven J. Cohen +13 more
semanticscholar +1 more source
Cellular interactions in the tumor microenvironment: the role of secretome [PDF]
, 2019 Over the past years, it has become evident that cancer initiation and progression depends on several components of the tumor microenvironment, including inflammatory and immune cells, fibroblasts, endothelial cells, adipocytes, and extracellular matrix ...
Castelo-Branco, Pedro +6 more
core +1 more source