Results 111 to 120 of about 14,776,627 (313)
Proceedings of the National Academy of Sciences, 2013 A typical cancerous tumor contains millions or even billions of cells harboring genetic mutations driving them to grow, divide, and invade the local tissue in which they’re embedded. However, as the cells proliferate, they don’t all stay in the neighborhood.
openaire +2 more sources
Cellular Automaton Model for Immunology of Tumor Growth [PDF]
arXiv, 1998 The stochastic discrete space-time model of an immune response on tumor spreading in a two-dimensional square lattice has been developed. The immunity-tumor interactions are described at the cellular level and then transferred into the setting of cellular automata (CA).
arxiv
Cancer and nonextensive statistics [PDF]
, 2006 We propose a new model of cancer growth based on nonextensive entropy. The evolution equation depends on the nonextensive parameter q. The exponential, the logistic, and the Gompertz growth laws are particular cases of the generalized model. Experimental data of different tumors have been shown to correspond to all these tumor-growth laws.
arxiv +1 more source
Clonal replacement of tumor-specific T cells following PD-1 blockade
Nature Network Boston, 2019 Immunotherapies that block inhibitory checkpoint receptors on T cells have transformed the clinical care of patients with cancer1. However, whether the T cell response to checkpoint blockade relies on reinvigoration of pre-existing tumor-infiltrating ...
K. Yost +15 more
semanticscholar +1 more source
Hepatocyte growth factor, a key tumor-promoting factor in the tumor microenvironment [PDF]
, 2017 The tumor microenvironment plays a key role in tumor development and progression. Stromal cells secrete growth factors, cytokines and extracellular matrix proteins which promote growth, survival and metastatic spread of cancer cells.
Galemmo, Robert +3 more
core +2 more sources
YKL-40 acts as an angiogenic factor to promote tumor angiogenesis
Frontiers in Physiology, 2013 A secreted glycoprotein YKL-40 also named chitinase-3-like-1 is normally expressed by multiple cell types such as macrophages, chondrocytes, and vascular smooth muscle cells.
Rong eShao
doaj +1 more source
Cytoneme-mediated signaling essential for tumorigenesis. [PDF]
, 2019 Communication between neoplastic cells and cells of their microenvironment is critical to cancer progression. To investigate the role of cytoneme-mediated signaling as a mechanism for distributing growth factor signaling proteins between tumor and tumor ...
Fereres, Sol +3 more
core +1 more source
Brazilian Journal of Medical and Biological Research, 1998 Macrophages are important components of natural immunity involved in inhibition of tumor growth and destruction of tumor cells. It is known that these cells can be activated for tumoricidal activity by lymphokines and bacterial products.
F. Ribeiro-Dias +5 more
doaj +1 more source
Bortezomib Augments Natural Killer Cell Targeting of Stem-Like Tumor Cells. [PDF]
, 2019 Tumor cells harboring stem-like/cancer stem cell (CSC) properties have been identified and isolated from numerous hematological and solid malignancies.
Ames, Erik +8 more
core +1 more source
Insights from a Novel Tumor Model: Indications for a Quantitative Link between Tumor Growth and Invasion [PDF]
arXiv, 2003 Using our previously developed model we demonstrate here, that (1) solid tumor growth and cell invasion are linked, not only qualitatively but also quantitatively, that (2) the onset of invasion marks the time point when the tumor cell density exceeds a compaction maximum, and that (3) tumor cell invasion, reduction of mechanical confinement and ...
arxiv