Results 111 to 120 of about 3,166,261 (352)
Molecular CancerMetastatic breast cancer remains largely incurable, partly due to our incomplete understanding of its intricate underlying mechanisms. Notably, intercellular communication mediated by small extracellular vesicles and particles (sEVPs) has emerged as a ...
Tasneem Cheytan +17 more
doaj +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Cytotoxic activity of anti-DNA slgA-antibodies from milk of healthy women
Біологічні студії, 2011 Earlier we have shown that immunoglobulin preparations derived from milk of healthy women by precipitation with 50% ammonium sulfate, possess toxic activity toward several transformed and tumor cells in vitro (Kit Y., and others, Biotechnology 2008).
M. O. Starykovych +2 more
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Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Behavior of tumors under nonstationary theraphy
, 2002 We present a model for the interaction dynamics of lymphocytes-tumor cells population. This model reproduces all known states for the tumor. Futherly,we develop it taking into account periodical immunotheraphy treatment with cytokines alone.
Bell +16 more
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Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Effects of Gliotoxin and Other Sulfur-Containing Compounds on Tumor Cells in vitro [PDF]
, 1951 John Mason, John G. Kidd
openalex +1 more source
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Trombin és ischémia együttes hatása a vér-agy-gát sejtjeire = The effects of thrombin and ischemia on the cells of the blood-brain-barrier [PDF]
, 2007 A vér-agy-gát (VAG) sejtjeiben, agyi kapilláris endotél sejtekben és asztrocitákban vizsgáltuk trombin és receptorainak kölcsönhatását.. A trombin szignalizáció meghatározott lépéseit tanulmányoztuk, az intracelluláris Ca szint változását és az ERK ...
Bartha, Katalin +4 more
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