Results 121 to 130 of about 15,400,316 (399)

S120: ACUTE MYELOID LEUKEMIA REPRESENTS A FERROPTOSIS-SENSITIVE CANCER ENTITY RAISING THE POSSIBILITY FOR NOVEL TARGETING STRATEGIES

HemaSphere, 2022
A. Narr, H. Alborzinia, E. Donato, F. Vogel, T. Boch, A.-M. Leppä, A. Waclawiczek, S. Renders, A. Schulze, A. Trumpp   +9 more
doaj   +1 more source

PD-L1 expression in squamous-cell carcinoma and adenocarcinoma of the lung

Radiology and Oncology, 2017
With introduction of immunotherapy (IT) into the treatment of advanced non-small-cell lung cancer (NSCLC), a need for predictive biomarker became apparent. Programmed death ligand 1 (PD-L1) protein expression is most widely explored predictive marker for
Janzic Urska, Kern Izidor, Janzic Andrej, Cavka Luka, Cufer Tanja   +4 more
doaj   +1 more source

Oncolytic Viruses—Interaction of Virus and Tumor Cells in the Battle to Eliminate Cancer

Frontiers in Oncology, 2017
Oncolytic viruses (OVs) are an emerging treatment option for many cancer types and have recently been the focus of extensive research aiming to develop their therapeutic potential.
Anwen Howells, Giulia Marelli, Nicholas R. Lemoine, Nicholas R. Lemoine, Yaohe Wang, Yaohe Wang   +5 more
doaj   +1 more source

Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics [PDF]

, 2018
Manu P. Kumar, Jinyan Du, Georgia Lagoudas, Jiao Yang, Andrew Sawyer, Daryl C. Drummond, Douglas A. Lauffenburger, Andreas Raue   +7 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Comprehensive Analysis of CXCR4, JUNB, and PD-L1 Expression in Circulating Tumor Cells (CTCs) from Prostate Cancer Patients

Cells
CXCR4, JUNB and PD-L1 are implicated in cancer progression and metastasis. The current study investigated these biomarkers in CTCs isolated from metastatic prostate cancer (mPCa) patients at the RNA and protein levels.
Argyro Roumeliotou, Areti Strati, Foteini Chamchougia, Anastasia Xagara, Victoria Tserpeli, Stavroula Smilkou, Elina Lagopodi, Athina Christopoulou, Emmanouil Kontopodis, Ioannis Drositis, Nikolaos Androulakis, Vassilis Georgoulias, Filippos Koinis, Athanasios Kotsakis, Evi Lianidou, Galatea Kallergi   +15 more
doaj   +1 more source

LncRNA XIST/miR-34a axis modulates the cell proliferation and tumor growth of thyroid cancer through MET-PI3K-AKT signaling [PDF]

, 2018
Hua Liu, Haoyu Deng, Yajie Zhao, Can Li, Yu Liang   +4 more
openalex   +1 more source

Immunosuppressive strategies that are mediated by tumor cells.

Annual Review of Immunology, 2007
Despite major advances in understanding the mechanisms leading to tumor immunity, a number of obstacles hinder the successful translation of mechanistic insights into effective tumor immunotherapy. Such obstacles include the ability of tumors to foster a
G. Rabinovich, D. Gabrilovich, E. Sotomayor   +2 more
semanticscholar   +1 more source

Androblastoma—Sertoli Cell Tumor

Journal of Urology, 1974
An androblastoma in an undescended testicle of a 43 yr old man is reported. Microscopically, the tumor showed zones of neoplastic cells varying in size and shape and separated by fibrous tissue. In some areas the cells were round with eosinophilic cytoplasm and round nuclei. No mitoses were seen.
Kalis, E.G., Goulandris, N.D.
openaire   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source