Results 131 to 140 of about 14,776,627 (313)
Molecules, 2016 Bullfrog oil is a natural product extracted from the Rana catesbeiana Shaw adipose tissue and used in folk medicine for the treatment of several diseases. The aim of this study was to evaluate the extraction process of bullfrog oil, to develop a suitable
Lucas Amaral-Machado +11 more
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Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors
Nature Communications, 2018 Identifying tumor antigen-specific T cells from cancer patients has important implications for immunotherapy diagnostics and therapeutics. Here, we show that CD103+CD39+ tumor-infiltrating CD8 T cells (CD8 TIL) are enriched for tumor-reactive cells both ...
T. Duhen +14 more
semanticscholar +1 more source
Frontiers in Immunology, 2017 Blocking interaction of the immune checkpoint receptor PD-1 with its ligand PD-L1 is associated with good clinical outcomes in a broad variety of malignancies. High levels of PD-L1 promote tumor growth by restraining CD8+ T-cell responses against tumors.
Eva M. Palsson-McDermott +6 more
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Cancer therapeutic potential of combinatorial immuno- and vaso-modulatory interventions [PDF]
arXiv, 2015 Currently, most of the basic mechanisms governing tumor-immune system interactions, in combination with modulations of tumor-associated vasculature, are far from being completely understood. Here, we propose a mathematical model of vascularized tumor growth, where the main novelty is the modeling of the interplay between functional tumor vasculature ...
arxiv
THE CYTOTOXIC ACTION OF IMMUNE GAMMA GLOBULIN AND COMPLEMENT ON KREBS ASCITES TUMOR CELLS [PDF]
, 1959 H. Green +3 more
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Frontiers in Immunology, 2019 Chimeric antigen receptor (CAR) T cells, T cells that have been genetically engineered to express a receptor that recognizes a specific antigen, have given rise to breakthroughs in treating hematological malignancies.
Marina C. Martinez, E. Moon
semanticscholar +1 more source
Multiphase modeling and qualitative analysis of the growth of tumor cords
, 2008 In this paper a macroscopic model of tumor cord growth is developed, relying on the mathematical theory of deformable porous media. Tumor is modeled as a saturated mixture of proliferating cells, extracellular fluid and extracellular matrix, that ...
Tosin, Andrea
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Electrophoretic analysis of the soluble proteins of cell fractions isolated from regenerating rat liver, liver tumor, and from liver of rats fedp-dimethylaminoazobenzene [PDF]
, 1953 Gaston de Lamirande +2 more
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Molecular Cancer, 2019 Tumor-associated macrophages (TAMs) are major components of tumor microenvironment that frequently associated with tumor metastasis in human cancers. Circulating tumor cell (CTC), originating from primary tumor sites, is considered to be the precursors ...
Chen Wei +8 more
semanticscholar +1 more source
Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor [PDF]
, 2011 Berberine, an isoquinoline alkaloid derived from plants, is a traditional medicine for treating bacterial diarrhea and intestinal parasite infections. Although berberine has recently been shown to suppress growth of several tumor cell lines, information ...
D. Brent Polk +8 more
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