Results 131 to 140 of about 15,400,316 (399)
Molecular CancerMetastatic breast cancer remains largely incurable, partly due to our incomplete understanding of its intricate underlying mechanisms. Notably, intercellular communication mediated by small extracellular vesicles and particles (sEVPs) has emerged as a ...
Tasneem Cheytan +17 more
doaj +1 more source
Metastasis and circulating tumor cells [PDF]
, 2012 Cancer is a prominent cause of death worldwide. In most cases, it is not the primary tumor which causes death, but the metastases. Metastatic tumors are spread over the entire human body and are more difficult to remove or treat than the primary tumor ...
Dalum, G. van +2 more
core +1 more source
Radiotherapy and CTLA-4 Blockade Shape the TCR Repertoire of Tumor-Infiltrating T Cells [PDF]
, 2017 Nils-Petter Rudqvist +9 more
openalex +1 more source
Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors
Nature Communications, 2018 Identifying tumor antigen-specific T cells from cancer patients has important implications for immunotherapy diagnostics and therapeutics. Here, we show that CD103+CD39+ tumor-infiltrating CD8 T cells (CD8 TIL) are enriched for tumor-reactive cells both ...
Thomas Duhen +14 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Fertility sparing surgery in malignant ovarian Germ cell tumor (MOGCT): 15 years experiences [PDF]
, 2021 Narges Zamani +4 more
openalex +1 more source
Frontiers in Immunology, 2019 Chimeric antigen receptor (CAR) T cells, T cells that have been genetically engineered to express a receptor that recognizes a specific antigen, have given rise to breakthroughs in treating hematological malignancies.
Marina C. Martinez, E. Moon
semanticscholar +1 more source
Tumor endothelial cells accelerate tumor metastasis
Cancer Science, 2017 Tumor metastasis is the main cause of cancer‐related death. Understanding the molecular mechanisms underlying tumor metastasis is crucial to control this fatal disease. Several molecular pathways orchestrate the complex biological cell events during a metastatic cascade.
Nako Maishi, Kyoko Hida
openaire +2 more sources
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Cytotoxic activity of anti-DNA slgA-antibodies from milk of healthy women
Біологічні студії, 2011 Earlier we have shown that immunoglobulin preparations derived from milk of healthy women by precipitation with 50% ammonium sulfate, possess toxic activity toward several transformed and tumor cells in vitro (Kit Y., and others, Biotechnology 2008).
M. O. Starykovych +2 more
doaj +1 more source