Frontiers in OncologyIntroductionDetection of PIK3CA mutations in primary tumors and liquid biopsy samples is of increasing importance for treatment decisions and therapy resistance in many types of cancer. The aim of the present study was to directly compare the efficacy of
Stavroula Smilkou +11 more
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Collagen I enhances the efficiency and anti-tumor activity of dendritic-tumor fusion cells
OncoImmunology, 2017 Low fusion efficiency and nominal activity of fusion cells (FCs) restrict the clinical application of dendritic cell (DC)/tumor fusion cells. Collagen I (Col I) is an interstitial collagen with a closely-knit structure used to repair damaged cell ...
Jian He +16 more
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Novel mechanisms for action of extremal agents: the role of transforming growth factor type beta
Біологічні студії, 2008 The article summarizes the results obtained during the last years at the Department headed by the article author, as well as literature data, on the role of transforming growth factor type beta in the action towards animal and human organisms of extremal
R. S. Stoika
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A mathematical study of the interaction between oxygen and lactate in an in-vivo and in-vitro tumor [PDF]
arXivMicro-environmental acidity is a common feature of the tumor. One of the causes behind tumor acidity is lactate production by hypoxic cells of the tumor. Hypoxia is a direct result of the establishment of oxygen gradients. It is commonly observed in the tumor in an in-vitro experimental setup and also in-vivo situation.
arxiv
Mathematical modeling of tumor therapy with oncolytic viruses: Effects of parametric heterogeneity on cell dynamics [PDF]
arXiv, 2006 One of the mechanisms that ensure cancer robustness is tumor heterogeneity, and its effects on tumor cells dynamics have to be taken into account when studying cancer progression. There is no unifying theoretical framework in mathematical modeling of carcinogenesis that would account for parametric heterogeneity.
arxiv
AN ELECTRON MICROSCOPE STUDY OF THE MORPHOLOGY AND DISTRIBUTION OF THE INTRACYTOPLASMIC "VIRUS-LIKE" PARTICLES OF EHRLICH ASCITES TUMOR CELLS [PDF]
, 1957 W. Robert Adams, Alfred M. Prince
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Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory. [PDF]
, 2019 PD-L1 on the surface of tumor cells binds its receptor PD-1 on effector T cells, thereby suppressing their activity. Antibody blockade of PD-L1 can activate an anti-tumor immune response leading to durable remissions in a subset of cancer patients ...
Belair, Cassandra D +10 more
core
Granular-cell tumors of the stalk and posterior lobe of the pituitary gland [PDF]
, 1955 Sarah A. Luse, James W. Kernohan
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Artificial intelligence enables precision diagnosis of cervical cytology grades and cervical cancer
Nature CommunicationsCervical cancer is a significant global health issue, its prevalence and prognosis highlighting the importance of early screening for effective prevention.
Jue Wang +23 more
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Immune targets in the tumor microenvironment treated by radiotherapy. [PDF]
, 2019 Radiotherapy (RT), the major anti-cancer modality for more than half of cancer patients after diagnosis, has the advantage of local tumor control with relatively less systematic side effects comparing to chemotherapy.
Li, Jian Jian +2 more
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